Dna Target Equipment & Supplies
28 equipment items found
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
XR5944 is an anti-tumor compound with DNA-targeting activity. As a topoisomerase inhibitor, XR5944 can effectively inhibit the activities of topoisomerase I and II. XR5944 shows excellent anti-tumor activity against human and mouse tumor cells in vitro and in vivo. XR5944 exhibits significant potency in multiple cell lines, with IC50 values of 0.04-0.4 nM. ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
XR5944 is an anti-tumor compound with DNA-targeting activity. As a topoisomerase inhibitor, XR5944 can effectively inhibit the activities of topoisomerase I and II. XR5944 shows excellent anti-tumor activity against human and mouse tumor cells in vitro and in vivo. XR5944 exhibits significant potency in multiple cell lines, with IC50 values of 0.04-0.4 nM. ...
Manufactured by:Massive Photonics GmbH based inMünchen, GERMANY
The MASSIVE-sdAB 1-PLEX Kit from Massive Photonics is designed for DNA-PAINT imaging applications, providing a camelid single-domain antibody (sdAB) to target mouse IgG kappa light chain or rabbit IgG. Engineered for precision, the sdAB is site-specifically coupled to a DNA-PAINT docking site, allowing for improved binding efficiency. ...
Manufactured by:Massive Photonics GmbH based inMünchen, GERMANY
The Primary Antibody Labeling Kit from Massive Photonics is designed for advanced FAST DNA-PAINT imaging, specifically targeting mouse IgG kappa light chain or rabbit IgG primary antibodies. This kit leverages camelid single-domain antibodies (sdABs) coupled to DNA-PAINT sites optimized for rapid imaging and high signal-to-noise ratios. ...
Manufactured by:Fusion Genomics Corporation based inBurnaby, BRITISH COLUMBIA (CANADA)
QUANTUMProbes, the second component of our ONETest molecular diagnostics assay kit, are comprised of synthetic non-reference based oligonucleotides designed using Fusion Genomics’ machine learning algorithms. ...
by:Linear Diagnostics Limited based inBirmingham, UNITED KINGDOM
Our patented linear dichroism and EXPAR technology have a number of distinct advantages including very rapid and accurate results, as well as the ability to detect multiple targets simultaneously.Linear dichroism works by detecting a shift in the plane of polarised light when a target is bound to a detector. Different molecular recognition methods can be used on ...
Manufactured by:Locus Biosciences, Inc. based inMorrisville, NORTH CAROLINA (USA)
CRISPR evolved as a bacterial immune system, which protects bacterial cells from invading viruses. Cas3 is a powerful exonuclease that shreds the DNA of targeted bacterial cells beyond repair, leading to rapid and predictable cell death. We use Cas3 to dramatically increase the potency of crPhage compared to their natural phage counterparts where we ensure that ...
Manufactured by:INOVIO Pharmaceuticals based inPlymouth Meeting, PENNSYLVANIA (USA)
INOVIO’s DNA medicines are made using a process called SynCon®. SynCon uses a proprietary computer algorithm that has been designed to identify and optimize the DNA sequence of the target antigen, whether it is a virus or a tumor. Once this sequence has been determined, the DNA is synthesized or reorganized, and ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
Mutations of IDH1 (isocitrate dehydrogenase 1,IDH1) can be found in glioblastoma and myeloproliferative neoplasm. Detection of IDH1mutations can be a positive predictor of a prognosis and a molecular marker for glioblastoma patients. On the other hand, it is reported that IDH1 mutations correlate with poor prognosis in myeloproliferative neoplasm. PNAClamp™ IDH1 Mutation Detection Kit is a ...
by:Eligo Bioscience based inParis, FRANCE
Eligobiotics are a first-in-class proprietary modality that enables the delivery and expression of therapeutic DNA in target bacterial populations of the microbiome. This technology allows modulation of the microbiome’s composition and function to address human disease with an unprecedented ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
BRAF mutation is found in several cancers including thyroid cancer, malignant melanoma, ovarian cancer, colorectal cancer. In case of thyroid cancer, there are over 40 different types of BRAF mutation. Of these mutations, the V600E mutation on exon 15, i.e. change of nucleotide from T to A in 1799th base that results in change from valine to glutamate in amino acids, is most important with over ...
Manufactured by:Solis BioDyne based inTartu, ESTONIA
Dye-based real-time quantitative PCR (qPCR) uses DNA binding dye to evaluate the DNA amplification process during PCR. In this mix EvaGreen® double-stranded DNA binding dye is used instead of the more widely used SYBR Green I that has similar fluorescence spectra. Compared to SYBR Green I dye EvaGreen® dye shows a higher fluorescence level, high sensitivity for detecting low template ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
According to the WHO report (2008), human papillomavirus (HPV) causes virtually 100% of cases of cervical cancers. There are more than 100 genotypes of HPV reported currently, and HPV consists of double helix circular DNA with ca. 7,900 bps. Compared to the traditional Pap smear test, HPV genotyping has several advantages; 1) high accuracy of determining existence of HPV viruses, 2) genotyping of ...
Manufactured by:ZenTech s.a. based inLiège, BELGIUM
The Targeted qPCR SMA uses the quantitative polymerase chain reaction to genotype the anterior spinal muscular atrophy (SMA) mutation in neonates on a dried blood sample. The test only identifies SMA homozygotes. This qualitative test is dedicated only to spinal muscular atrophy (SMA) newborn screening and is performed on a dried blood sample on 903® or 226 blotted paper. Parameter ; ...
by:Intellia Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Genome editing is efficient, precise and scalable. CRISPR/Cas9 genome editing can make permanent, precisely targeted changes in patients’ chromosomes and repair the underlying genetic mutation, whereas more traditional gene therapy typically involves introducing a non-permanent copy of a gene into patients’ cells. These attributes of CRISPR/Cas9 provide a significant ...
by:Thermo Fisher Scientific, LIMS & Laboratory Software based inPhiladelphia, PENNSYLVANIA (USA)
qPCR system for quantitation of residual plasmid DNA. Multiplex assay that targets all kanamycin resistance (KanR) gene alleles common in bioproduction. Highly specifi c quantitation through innovative DNA-free master mix. Highly sensitive quantitation using proven Applied Biosystems TaqMan real-time PCR technology. ...
Manufactured by:Celemics, Inc. based inSeoul, SOUTH KOREA
“Unlike Whole Genome Sequencing, Targeted Sequencing is a technique that selectively analyzes specific regional sequences of genomes.” Our Target Enrichment Panel uses hybridization-based capture technology to enable the core process of Target Sequencing, which is the separation and analysis of specific regional sequences of entire genomes. It can also accurately analyze all types of ...
Manufactured by:Fluxergy based inIrvine, CALIFORNIA (USA)
Simple Molecular Testing and More at Your Practice. Fluxergy provides a solution that eliminates the Friday dilemma of waiting for lab results on the weekend. Design and build PCR tests at your practice that give you results within 1 ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
KRAS mutation is found in several cancers such as pancreatic cancer, colorectal cancer, lung cancer, biliary tract cancer and thyroid cancer. The existence of KRAS mutations is often related with a prognostic marker to drug response. For example, KRAS mutation is considered a strong prognostic marker for drug response of tyrosine kinase inhibitors such as Gefitinib (Iressa) or Erlotinib ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Guadecitabine (SGI-110) is a second-generation DNA methyltransferases (DNMT) inhibitor for research of acute myeloid leukemia (AML) and myelodysplastic syndromes ...