Drug Metabolism Equipment & Supplies
37 equipment items found
Manufactured by:ViennaLab Diagnostics GmbH based inVienna, AUSTRIA
Genetic variants of the drug-metabolizing enzyme CYP2C9 lead to high inter-individual dose response variability of certain drugs, in particular coumarin-based anticoagulants. The CYP2C9 mpx RealFast™ Assay allows for the simultaneous detection of CYP2C9*2 and CYP2C9*3 variants exhibiting impaired enzyme ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory[5], antibacterial[4], antitumor[1] therapies, as well as drug metabolism ...
Manufactured by:Genabio Diagnostics Inc. based inBedford, MASSACHUSETTS (USA)
Intended use: Wondfo® T-Square Oral Fluid Drug Test is a simple and convenient method of drug screening. Full observation during collection allows the testing to be performed anytime and anywhere, which greatly reduces the specimen-tampered concerns. Because it takes time for drug to metabolize and pass through body, oral ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic non-parenchymal cells (NPCs) represent about 30% of the liver and are specialized cells which interact with hepatocytes for several functions. For this reason, liver co-cultures may increase the sensitivity of liver models for ADME/Tox-related research by recapitulating the complexity of a whole liver. "Mix NPCs" provides a mix of different types of liver cells, including Kupffer cells, ...
Manufactured by:Allevi, Inc. based inPhiladelphia, PENNSYLVANIA (USA)
Clinically relevant drug-drug interactions (DDI) are a serious concern for any new drug development project. To better support capturing the multiple mechanisms of DDI potential using primary hepatocytes, we now offer Interaction Qualified Human Hepatocytes (Catalog HUCPI) which are characterized for 3 major mechanisms of DDI: transporter activity, enzyme activity, and induction potential, ...
Manufactured by:Ahlstrom based inEspoo, FINLAND
Easy Collection - Reliable and Quantitative Analysis - Design for Automation. Ahlstrom AutoCollect card is designed for dried blood spot (DBS) microvolume sampling, transport and storage at ambient ...
by:Wondfo USA Co Ltd. based inWillowbrook, ILLINOIS (USA)
SAFElife Oral Fluid Testing is a simple and convenient method of drug screening. Full observation during collection allows the testing to be performed anytime and anywhere, which greatly reduces specimen tamper concerns. Because it takes time for drugs to metabolize and pass through the body, oral fluid is recognized as the optimal ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Acquisition of hepatocyte samples is now a critical step for research activities. The limited availability of human hepatocytes makes cryopreservation a good option to provide researchers with a sufficient amount of viable liver ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic stellate cells (HSC) are also known as perisinusoidal cells and they are located in the space of disses. These cells are the major cell type involved in liver fibrosis in response to liver injury and they play a key role in the homeostasis of liver extracellular matrix, repair, regeneration and fibrosis, and control retinol metabolism, storage and ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
The fresh human hepatocytes we offer are obtained and isolated from human donors for research purposes. These cells are a superior in-vitro model because they thrive in an environment closely resembling the in-vivo host ...
Manufactured by:NOWDiagnostics Inc. based inSpringdale, ARKANSAS (USA)
The ADEXUSDx Acetaminophen Test is an enzymatic assay used for the qualitative detection of elevated acetaminophen levels in human whole blood, plasma, or serum samples. It can be used as an aid for healthcare professionals in the diagnosis of acetaminophen ...
Manufactured by:Quay Pharma based inFlintshire, UNITED KINGDOM
Lipophilic systems have proven effectiveness in improving bioavailability by helping drugs to overcome problems like poor gastric solubilisation, degradation and elimination due to first-pass metabolism in the liver, other types of pre-systemic metabolism, and drug transport and efflux effects. At Quay Pharma, we are highly ...
Manufactured by:Eton Bioscience, Inc. based inSan Diego, CALIFORNIA (USA)
Galactose is a monosaccharide that can be found in milk, and it is involved in different biological processes in human body.Eton's Galactose Assay Kit provides a simple and reliable method for quantifying galactose in biological samples, such as serum,plasma,cell culture media etc. In the assay, Galactose is oxidized by enzyme reactions to yield color product, which can be measured at 570nm for ...
Manufactured by:Lumen Bioscience, Inc. based inSeattle, WASHINGTON (USA)
Cardiometabolic disease (CMD)—a cluster of related conditions that includes obesity, diabetes, and cardiovascular disease—afflicts hundreds of millions of people worldwide, and the associated health and economic burdens continue to grow. An estimated 17.9 million people died from CMD in 2019, representing nearly a third of all global deaths. Of these deaths, 85% were due to heart ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Primary animal hepatocytes and subcellular liver fractions (Microsomes, Cytosol and S9 fraction) are model systems often used for a variety of in vitro screenings and analyses prior to clinical studies in human and animal health as well as environmental toxicology. Hepatocytes in suspension are preferable for short-term studies whereas plated hepatocytes are more useful for long-term ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Sorafenib-d3 (Donafenib), a deuterated compound of Sorafenib, is the first deuterium-generation tumor suppressor small molecule. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, ...
Manufactured by:Technopath Clinical Diagnostics based inBallina, IRELAND
Increase laboratory efficiencies - Reduce handling time, reclaim storage space, reduce lot evaluation time, reduce packaging waste, reduce dead-volume waste with Multichem IA Plus - consolidated Third Party immunoassay QC ...
by:Oncodesign based inDijon, FRANCE
Oncodesign’s Pharmimage® technology module is a pharmaco-imaging module designed to monitor the effect of treatments and to define effective translational biomarkers in precision medicine. It includes translational, optical (bioluminescence, fluorescence), functional and molecular (MRI, PET, SPECT, CT scanner, MRI/PET coupling) multi-modal imaging capabilities, adapted to small rodents ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular ...