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Drug Response Equipment & Supplies
24 equipment items found
Manufactured by:Obsidian Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Our proprietary cytoDRiVE® platform leverages drug responsive domains (DRDs) to control protein function using an FDA-approved small ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
KRAS mutation is found in several cancers such as pancreatic cancer, colorectal cancer, lung cancer, biliary tract cancer and thyroid cancer. The existence of KRAS mutations is often related with a prognostic marker to drug response. For example, KRAS mutation is considered a strong prognostic marker for drug response of tyrosine ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
NRAS mutation is found in several cancers such as melanoma (13~25%), colorectal cancer (1~6%), lung cancer (1%), thyroid cancer (7%) and hepatocellular carcinoma (10%). It is know that the drug response against colorectal cancer medicine such as Erbitux and Cetuximab decreased and the prognosis of the metastatic colorectal cancer patient is bad if the patient has ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
Usually, it is hard to find lung cancer in the early stage and is diagnosed as lung cancer when it is already progressed. So the prognosis tends to be bad. It is known that the patients with EGFR mutation show very high drug responses against EGFR tyrosine kinase inhibitor (TKI) such as Gefitinib (Iressa, AstraZenca) and Erlotinib (Tarceba, Roche). We expect that ...
Manufactured by:Microbiotica Limited based inLittle Chesterford, UNITED KINGDOM
Microbiotica accesses high quality large-scale clinical datasets in order to identify microbiome-based biomarkers of drug response, drug side-effects or disease progression. The company has accessed the clinical data from academic/clinical collaborations (University of Adelaide, Cambridge University Hospitals/Cancer Research UK) or from pharma ...
Manufactured by:DX Fluidics based inSuzhou, CHINA
They utilize precise microstructures to manipulate and observe cells at a microscopic scale. Applications include drug screening, disease modeling, and tissue engineering. Various types are used in research, such as lung and heart tissue chips, which mimic organ structures and functions, providing insights into physiological and pathological processes. Microfluidic PEEK chips and ...
by:Wondfo USA Co Ltd. based inWillowbrook, ILLINOIS (USA)
While it is used clinically for severe pain, most fentanyl-related overdose cases are linked to its presence in illegal drug markets. In response to this crisis, the SAFEIife- Fentanyl (FTY) Liquid & Powder Drug Test Strip can determine if fentanyl is present in a liquid or powder, providing vital information to help with harm ...
by:Joanneum Research Forschungsgesellschaft mbH based in
These models include different skin layers such as epidermis, dermis and subcutis and provide a fully intact three-dimensional skin architecture. Our models offer a variety of advantages: They enable the study of skin toxicity, drug penetration, inflammatory responses and more in an ex-vivo environment. This enables us to generate precise and meaningful data, ...
Manufactured by:Microbiotica Limited based inLittle Chesterford, UNITED KINGDOM
A fundamental challenge to any microbiome program is that human gut bacteria have been viewed as unculturable, and the microbiome of any individual could not be characterised with sufficient depth and precision to form a sound basis for translation. Thus metagenomics routinely can classify only 50 % of gut bacterial sequences, meaning that a very large fraction of gut bacteria are not seen, ...
Manufactured by:XILIS, Inc. based inDurham, NORTH CAROLINA (USA)
Xilis’ proprietary MicroOrganoSphere (MOS) technology represents a new standard in patient-derived micro-tumor production. From each patient, MOS retains unique patient tissue structure, genetic alterations, gene expression, immune microenvironment and histopathology. Overcoming major limitations of widely used, yet limited, models including xenografts and organoids, MOS offers ...
Manufactured by:Lexogen GmbH based inVienna, AUSTRIA
SLAMseq is a high-sensitivity method for time-resolved measurement of newly synthesized and existing RNA in cultured cells. SLAMseq enables resolution of RNA synthesis and degradation kinetics. Lexogen offers a family of kits based on the new SLAMseq method: Thiol (SH)-Linked Alkylation for the Metabolic sequencing of RNA. SLAMseq enables the identification and quantification of newly synthesized ...
Manufactured by:GeneCentric Therapeutics, Inc. based inDurham, NORTH CAROLINA (USA)
GeneCentric has developed two gene expression profilers (LSP 210 and LSP 220) that define molecular subtypes of the two most common forms of non-small cell lung cancer (NSCLC), squamous cell carcinoma, and ...
Manufactured by:Exscientia based inOxford, UNITED KINGDOM
In the landmark study, it was demonstrated for the first time that our functional precision-oncology platform can improve patient outcome in a prospective interventional ...
Manufactured by:BTNX Inc. based inPickering, ONTARIO (CANADA)
The Rapid Response Saliva Drug Test is an easy to use, on-site saliva drug test with built-in test strips. This oral fluid test is a rapid, qualitative screening test that simultaneously detects Marijuana (THC), at the cut-off level of 30 ng/mL, and/or Cotinine (COT), at the cut-off level of 40 ng/mL, in human oral fluid. This multi panel ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Angiogenesis, the sprouting of new blood vessels from pre-existing vasculature, plays an important role in the maintenance of body homeostasis and the progression of cancer and Alzheimer’s disease, among others. Studying vessel formation can help identify and validate targets and candidates for treatment of a variety of diseases. Using Ncardia’s human iPSC-derived endothelial cells, ...
by:Hummingbird Diagnostics GmbH based inHeidelberg, GERMANY
MiRNAs are small, highly conserved, non-coding RNAs playing crucial roles in the regulation of virtually all aspects of living ...
Manufactured by:HemoShear Therapeutics, Inc. based inCharlottesville, VIRGINIA (USA)
HST5040 is an investigational small molecule therapy being developed by HemoShear to reduce the levels of toxins associated with methylmalonic acidemia (MMA) and propionic acidemia (PA), rare genetic disorders caused by the de?ciency of certain enzymes required to metabolize amino acids. HST5040 is formulated for convenient daily administration at home as a liquid taken either orally or through a ...
Manufactured by:Cytocast based inBudapest, HUNGARY
The CYTOCAST DIGITAL TWIN Platform represents a cutting-edge advancement in precision medicine, aiming to transform patient care through personalized treatment strategies. By integrating multi-omics data—such as genomic, proteomic, and metabolomic profiles—with detailed clinical information, this platform creates a precise digital replica of each patient's unique biological ...
Manufactured by:Amoy Diagnostics Co., Ltd. based inXiamen, CHINA
Neurotrophic tropomyosin-related kinase (NTRK) is a group of high affinity nerve growth factor (NGF) receptors, including tropomyosin receptor kinases (Trk) A, B, and C which are encoded by NTRK1, NTRK2, and NTRK3 genes, respectively. NTRK proteins, upon NGF ligand binding, function in the phosphorylation of members of the RAS/MAPK, PI3K/AKT, PLC-y pathways that play a key role in cell ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
APD668 is a potent, selective and orally active agonist of G-protein coupled receptor GPR119, with EC50s of 2.7 nM and 33 nM for hGPR119 and rGPR119, respectively. APD668 shows no significant inhibition of any of the five major CYP isoforms with the exception of CYP2C9 (Ki=0.1 μM). APD668 can be used for the research of steatohepatitis and ...