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Epidermal Growth Factor Receptor 2 Equipment & Supplies
12 equipment items found
Manufactured by:Virasoft Inc. based inSarıyer, TURKEY
The HER2 gene is an oncogene encoding the “Epidermal Growth Factor Receptor 2” which is a transmembrane glycoprotein. Amplification of the HER2 gene and overexpression of HER2 receptor on the cell membrane is observed in approximately %15 of invasive breast ...
Manufactured by:Cerca Biotech based inBerlin, GERMANY
ERBB2 is the name of the gene for human epidermal growth factor receptor 2 (HER2). This receptor is a cell surface protein which belongs to the family of epidermal growth factor receptors. ERBB2 activation stimulates cell ...
Manufactured by:Shanghai Henlius Biotech, Inc based inShanghai, CHINA
HLX22, humanised IgG1 monoclonal antibody injection targeting human epidermal growth factor receptor-2 (HER2). First patient has been dosed in Phase 2 clinical trial to compare HLX22 in combination with trastuzumab and chemotherapy as first-line therapy for HER2-positive locally advanced or ...
Manufactured by:Amoy Diagnostics Co., Ltd. based inXiamen, CHINA
PI3K plays a key role ofPI3K/Akt signaling pathway in numerous cellular processes critical for cancer progression, including metabolism, growth, survival, and motility. Somatic mutations in the PIK3CA gene are found in many types of cancer, including approximately 40% of patients with hormone receptor (HR)-positive, human epidermal ...
Manufactured by:Oxford Gene Technology IP Limited based inOxford, UNITED KINGDOM
The HER2 amplification probe consists of a 347kb probe labelled in red, spanning the HER2 (ERBB2) gene and neighbouring regions, and a green probe for the chromosome 17 ...
Manufactured by:StressMarq Biosciences Inc. based inVictoria, BRITISH COLUMBIA (CANADA)
Product Name: HER2 Antibody (pTyr877). Description: Rabbit Anti-Human HER2 (pTyr877) Polyclonal. Species Reactivity: Human, Mouse, Rat. Applications: WB, IHC, IP, ELISA. Antibody Dilution: WB (1:250-1:1000); IHC (1:50-1:150); IP (1-2.5 ug per mg lysate); ELISA (1:5000); optimal dilutions for assays should be determined by the user. Host Species: Rabbit. Immunogen Species: Human. Immunogen: ...
Manufactured by:Immunodiagnostic Systems Holdings PLC based inBoldon Colliery, UNITED KINGDOM
LISA-TRACKER anti-Trastuzumab is an enzyme linked immunoassay (ELISA) for the quantitative determination of anti-Trastuzumab antibodies in human serum ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
TAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity[1]. TAK-285 can cross the blood-brain barrier ...
Manufactured by:Therawis based inMunich, GERMANY
Personalized medicine aims to identify patients who require treatment and subsequently select the right therapy based on individual factors and tumor characteristics, i.e. personalized medicine targets to identify the right patients for the right therapy. Prognostic biomarkers provide information on the risk of disease recurrence whereby predictive ones will inform the physician of the potential ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
CUDC-101 is a potent inhibitor of HDAC, EGFR, and HER2 with IC50s of 4.4, 2.4, and 15.7 nM, respectively. CUDC-101 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway. Oxymatrine inhibits bocavirus minute virus of canines (MVC) replication, reduces viral gene expression and decreases apoptosis induced by viral ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agent, and induces apoptosis, arrests cancer cells in G0/G1 phase. Mevastatin also increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. Mevastatin has antitumor activity and has the potential for cardiovascular diseases ...