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- Exosomes - Extracellular Vesicles for Validation and Quality Control
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Exosomes Equipment & Supplies
38 equipment items found
Manufactured by:Omnia Biotech based inStockholm, SWEDEN
The Pure•SAL™ Oral Specimen Collection Kit provides a simple non-invasive and rapid platform for isolating “liquid biopsy” specimens including cell free DNA, cell free RNA, exosomes, or proteins in a single step. The harvested, purified saliva specimen is stabilized if required and available for downstream PCR, genotyping, sequencing, proteomics and other ...
Manufactured by:INOVIQ Ltd based inNotting Hill, AUSTRALIA
EXO-NET RUO - a pan-exosome capture tool for isolation of exosomes from body fluids including plasma, urine, and saliva. Exosomes are small membrane-enclosed vesicles actively secreted by most cells into biological fluids including serum, plasma, urine, breast milk, and saliva [1]. Studies have found that the analysis of ...
Manufactured by:Therawis based inMunich, GERMANY
Interest in exosome research has increased dramatically in recent years due to their unique functions as intercellular messengers, abilities to alter recipient cell bioactivities, as well as in disease diagnostics. Despite significant efforts made in this relatively new field of research, progress has been held back by challenges such as inefficient separation methods, ...
Manufactured by:Evox Therapeutics Limited based inOxford, UNITED KINGDOM
Evox’s proprietary protein engineering technology enables loading of protein therapeutics and tissue targeting moieties onto the surfaces of exosomes, which allows targeting and display of therapeutic proteins to an organ of ...
Manufactured by:Evox Therapeutics Limited based inOxford, UNITED KINGDOM
Nucleic acid-based therapeutics constitute a core therapeutic modality for Evox’s development programs, and we have sophisticated capabilities for the loading of various nucleic acids (primarily RNAs) into ...
Manufactured by:Therawis based inMunich, GERMANY
Exosomes (30-150 nm) are the smallest type of extracellular microvesicles (EMV), produced through inward budding multivesicular bodies (MVB), resulting in intra-luminal vesicles (ILV). ILVs are released into the extracellular media by exocytosis. Exosome-associated proteins are used to isolated microvesicles from biological fluids such as blood, urine or cerebral ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Doxorubicin hydrochloride inhibits human DNA topoisomerase I with an IC50 of 0.8 μM. Doxorubicin hydrochloride also increases exosome ...
Manufactured by:Exosome Diagnostics, Inc. based inWaltham, MASSACHUSETTS (USA)
The only exosome-based test that provides unique, actionable intelligence to help you decide if biopsy is necessary; independent of PSA and other standard of care (SOC) features. Connect with a representative in your area for more information today. ...
Manufactured by:Nanovex Biotechnologies based inLlanera, SPAIN
Exosomes are extracellular vesicles of natural origin that are produced by all cell types in the range of 40 to 160 nm. They have a key role in cell-to-cell communication and have been proved to be powerful tools in diagnosis and therapeutics. Their basic structure is very similar to liposomes, consisting of double lipid which is a slice of cell membrane and an aqueous based core ...
Manufactured by:Alphageneron based inCambridge, MASSACHUSETTS (USA)
An allogenic NK cell therapy that targets tumors expressing mHsp70. Patients are selected with high mHsp70 exosomes in their blood using our Companion Diagnostic AP-CDx (described below). We obtain PBMCs from healthy donors by apheresis, their NK cells are expanded, and incubated ex vivo with TKD and IL-2, followed by freezing, thawing and intravenous administration to ...
Manufactured by:Oasis Diagnostics based inVancouver, WASHINGTON (USA)
The Pure•SAL Oral Specimen Collection Kit provides a simple non-invasive and rapid platform for isolating “liquid biopsy” specimens including cell free DNA, cell free RNA, exosomes, or proteins in a single step. The harvested, purified saliva specimen is stabilized if required and available for downstream PCR, genotyping, sequencing, proteomics and other ...
Manufactured by:Capricor Therapeutics, Inc. based inSan Diego, CALIFORNIA (USA)
It is being investigated for its potential to modify the immune system’s activity to encourage cellular regeneration. The cells function by releasing exosomes that are taken up largely by macrophages and T-cells and begin a cycle of ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist, apoptosis inducer, and common disease inducer in experimental animals, constructing models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Manumycin A can inhibit the Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration resistant prostate cancer cells to suppress exosome biogenesis and ...
Manufactured by:Exosome Diagnostics, Inc. based inWaltham, MASSACHUSETTS (USA)
The ExoDx Prostate is a simple, non-invasive urine test that can discriminate the risk of aggressive prostate cancer (defined as Gleason Score ≥7). This test is now available as an At-Home Collection Kit that can be initiated by an electronic order signed by the physician and sent directly to the patient’s home for ...
Manufactured by:Evox Therapeutics Limited based inOxford, UNITED KINGDOM
Phenylketonuria, or PKU, is an autosomal recessive inborn error of phenylalanine metabolism resulting in a deficiency of the hepatic enzyme phenylalanine hydroxylase ...
Manufactured by:Evox Therapeutics Limited based inOxford, UNITED KINGDOM
The Evox portfolio includes granted and pending applications in the world's major pharmaceutical markets, including USA, Europe, Japan, China as well as various other jurisdictions. In addition to the patent portfolio Evox also safeguards its intellectual property by the maintenance of several trademarks, copyrights, and trade secrets which together form broad and deep protection for the ...
Manufactured by:Evox Therapeutics Limited based inOxford, UNITED KINGDOM
Targeted delivery of nanoparticles is an area that has been intensively researched. Targeted drug delivery has a role to play in the delivery of many if not all drugs, but targeted delivery systems are critical for the delivery of nucleic acid-based agents such as siRNA and CRISPR-Cas ...
Manufactured by:Omnia Biotech based inStockholm, SWEDEN
RNAPro•SAL™ was developed as an easy to use and cost effective tool for the split sample collection of rich sources of RNA miRNA, mRNA and proteins found in saliva. The proprietary RNAPro•SAL™ kit provides two equivalent samples of saliva which total 1.0 mL of saliva in 1-3 minutes. These may be analyzed later for either RNA or protein components. A unique built in Sample ...