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Fatty Liver Disease Equipment & Supplies

23 equipment items found

G3T - Pharmaceutical Pipeline

G3T - Pharmaceutical Pipeline

Manufactured by:G3T Therapeutics   based inMidlothian, VIRGINIA (USA)
All drugs targeting cardiovascular disease currently on the market work by lowering cholesterol levels. G3T identified and genetically validated an entirely novel biological mechanism and potential drug target that treats both cardiovascular disease, as well as non-alcoholic fatty liver disease. ...
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Model ALT-801 - Dual GLP-1/Glucagon Agonist For NASH

Model ALT-801 - Dual GLP-1/Glucagon Agonist For NASH

Manufactured by:Altimmune Inc.   based inGaithersburg, MARYLAND (USA)
A peptide-based dual GLP-1/glucagon receptor agonist designed to treat the metabolic dysfunction that causes non-alcoholic steatohepatitis (NASH). NASH, the most severe form of non-alcoholic fatty liver disease (NAFLD), involves multiple metabolic pathways leading to the abnormal accumulation of liver fat, toxic lipid ...
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InSphero 3D InSight - Model Steatosis - Advanced Human Disease

InSphero 3D InSight - Model Steatosis - Advanced Human Disease

Manufactured by:InSphero AG   based inSchlieren, SWITZERLAND
The 3D InSight™ Steatosis Model is an advanced human disease model that enables you to screen compounds and investigate disease pathophysiology using a physiologically relevant human liver microtissue that recapitulates the first stage of non-alcoholic fatty liver disease: ...
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MedChemExpress - Model Epeleuton - 1667760-39-5

MedChemExpress - Model Epeleuton - 1667760-39-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Epeleuton is a second-generation synthetic n-3 fatty acid derivative that mainly targets the regulation of blood lipids, blood sugar and inflammatory responses. In clinical trials, Epeleuton significantly reduced triglycerides, very low-density lipoprotein cholesterol and total cholesterol without increasing low-density lipoprotein cholesterol levels. ...
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Q-Plex - Model GBP-28, apM1, AdipoQ, Acrp30 - Human Adiponectin Analyte

Q-Plex - Model GBP-28, apM1, AdipoQ, Acrp30 - Human Adiponectin Analyte

Manufactured by:Quansys Biosciences Inc.    based inLogan, UTAH (USA)
Adiponectin is a protein hormone generated by adipose tissue that is involved in glucose regulation and fatty acid breakdown. Though the hormone is produced by fat cells, its levels are reduced in obese individuals and increase with caloric restriction and weight reduction. In lean individuals, the adiponectin is produced by adipose tissue in bone marrow. Decreased ...
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JDB - Non-Alcoholic Steatohepatitis (NASH)

JDB - Non-Alcoholic Steatohepatitis (NASH)

Manufactured by:JD Bioscience Inc. (JDB)   based inBuk-gu, SOUTH KOREA
NASH, an advanced form of non-alcoholic fatty liver disease (NAFLD), can progress to liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Genetic factors, environmental factors, and microbiome alterations are mainly involved in disease progression. Experts estimated that 24% of U.S. adults have NAFLD ...
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MedChemExpress - Model Acetylshikonin - 24502-78-1

MedChemExpress - Model Acetylshikonin - 24502-78-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Acetylshikonin is a inhibitor of acetylcholinase (AChE) (IC50=34.6 μM) and nonselective cytochrome P450. Acetylshikonin can induce Apoptosis and Autophagy in cancer cells. Acetylshikonin regulates blood glucose, liver fat metabolism, and renal fibrosis, and is used in the study of diabetes, diabetic nephropathy (DN), obesity, and nonalcoholic fatty ...
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InSphero 3D InSight - Model NASH - Advanced 3D Human Liver Disease

InSphero 3D InSight - Model NASH - Advanced 3D Human Liver Disease

Manufactured by:InSphero AG   based inSchlieren, SWITZERLAND
Test efficacy of anti-NASH drugs in an advanced 3D human liver disease model. The InSphero 3D InSight™ Human Liver NASH Model consists of an advanced microtissue co-culture of healthy primary human liver cells combined with specially formulated media and cocktails that induce the progression of NAFLD and NASH from steatosis ...
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Liver Disease (Nash) and Ascites

Liver Disease (Nash) and Ascites

Manufactured by:Sequana Medical NV   based inSint-Denijs Westrem, BELGIUM
Liver disease, a large and growing market globally. Cirrhosis is late-stage liver disease which occurs when scar tissue (fibrosis) replaces healthy tissue. Alcohol and viral hepatitis B and C are common causes of cirrhosis, although there are many other causes including non-alcoholic fatty liver ...
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MedChemExpress - Model Calenduloside E - 26020-14-4

MedChemExpress - Model Calenduloside E - 26020-14-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Calenduloside E alleviates atherosclerosis by regulating macrophage polarization, improves mitochondrial function by regulating the AMPK-SIRT3 pathway, and alleviates acute liver injury. In addition, Calenduloside E promotes the interaction between L-type calcium channels and Bcl-2 related apoptosis genes, inhibits calcium overload, and alleviates myocardial ischemia/reperfusion ...
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Kepro - Fatty Liver Test Kit

Kepro - Fatty Liver Test Kit

Manufactured by:Kepro   based inDeventer, NETHERLANDS
Fatty liver test to determine fatty liver ...
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CohBar - Model CB4211 - Biotechnology for Nonalcoholic Steatohepatitis (NASH) and Obesity

CohBar - Model CB4211 - Biotechnology for Nonalcoholic Steatohepatitis (NASH) and Obesity

by:CohBar, Inc.   based inMenlo Park, CALIFORNIA (USA)
We believe CB4211 offers a differentiated approach to treating nonalcoholic steatohepatitis (NASH) and obesity. Is a novel and improved analog of MOTS-c, a naturally occurring mitochondrial derived peptide (MDP) that plays a key role in regulating metabolism. Has resulted in significant impacts on NASH and obesity in multiple preclinical models. Has been shown in a clinical study to significantly ...
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MedChemExpress - Model Larsucosterol sodium - 1174047-40-5

MedChemExpress - Model Larsucosterol sodium - 1174047-40-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Larsucosterol (DUR-928) sodium, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol sodium as a potent endogenous regulator decreases lipogenesis. Larsucosterol sodium inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of ...
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MedChemExpress - Model Elobixibat - 439087-18-0

MedChemExpress - Model Elobixibat - 439087-18-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Elobixibat (A 3309; AZD 7806) is an orally effective Apical Sodium-Dependent Bile (IBAT) inhibitor, with an IC50 value of 0.53 nM (human IBAT ), 0.13 nM (mouse IBAT), 5.8 nM (canine IBAT). Elobixibat lowers LDL cholesterol, increases serum GLP-1, promotes colon motility, and has the potential to treat metabolic syndrome. Elobixibat can be used to study constipation, dyslipidemia, non-alcoholic ...
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MedChemExpress - Model Cenicriviroc - 497223-25-3

MedChemExpress - Model Cenicriviroc - 497223-25-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Cenicriviroc (TAK-652) is an orally active, dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective ...
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MedChemExpress - Model Larsucosterol - 884905-07-1

MedChemExpress - Model Larsucosterol - 884905-07-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Larsucosterol (DUR-928), a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol as a potent endogenous regulator decreases lipogenesis. Larsucosterol inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of ...
CONTACT SUPPLIER

MedChemExpress - Model Fasudil Hydrochloride - 105628-07-7

MedChemExpress - Model Fasudil Hydrochloride - 105628-07-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and ...
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Glycotest Technology

Glycotest Technology

by:Glycotest, Inc   based inMerion, PENNSYLVANIA (USA)
Glycotest blood tests are being developed to provide information on the likelihood of serious liver disease like cancer or fibrosis-cirrhosis by employing technology designed to measure two kinds of disease signals: The amount of the monosaccharide fucose that appears abnormally on certain serum glycoproteins—to indicate likelihood of disease. The pattern of glycoproteins that is abnormally ...
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MedChemExpress - Model Celecoxib - 169590-42-5

MedChemExpress - Model Celecoxib - 169590-42-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 ...
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MedChemExpress - Model Seladelpar - 851528-79-5

MedChemExpress - Model Seladelpar - 851528-79-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Seladelpar (MBX-8025) is an orally active, potent and specific PPARδ agonist with an EC50 of 2 nM. Seladelpar shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar can be used for the study of primary biliary ...
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