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Human Disease Equipment & Supplies
66 equipment items found
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
The 3D InSight™ Steatosis Model is an advanced human disease model that enables you to screen compounds and investigate disease pathophysiology using a physiologically relevant human liver microtissue that recapitulates the first stage of non-alcoholic fatty liver disease: accumulation of lipids in ...
Manufactured by:Systasy Bioscience GmbH based inMunich, GERMANY
The DiseasePROFILER uses a subset of top-performing sensors identified in the PathwayPROFILER assay and enables simple, robust, and cost-effective screening of compound effects in human disease models. ...
Manufactured by:Regeneron Pharmaceuticals Inc. based inTarrytown, NEW YORK (USA)
This enables unprecedented speed and capacity for the validation of therapeutic targets and the creation of animal models of human disease. We have a long history and deep expertise in mouse genetics — in 2006, VelociGene was selected by the National Institutes of Health (NIH) as part of its Knockout Mouse Project, an unprecedented effort to determine the ...
by:Eligo Bioscience based inParis, FRANCE
Eligobiotics are a first-in-class proprietary modality that enables the delivery and expression of therapeutic DNA in target bacterial populations of the microbiome. This technology allows modulation of the microbiome’s composition and function to address human disease with an unprecedented ...
Manufactured by:Trailhead Biosystems Inc. based inBeachwood, OHIO (USA)
We are developing human endothelial cells from human (non-embryo) induced pluripotent stem cells (iPSCs). Our novel protocol will allow us to make endothelial cells at scale. We will make our endothelial cells available for drug discovery, organ or tissue printing, high throughput or high content screening, toxicity and efficacy testing, and ...
Manufactured by:Microviable Therapeutics SL based inGijón, SPAIN
Microviable Therapeutics is developing novel technologies and next generation biotherapeutic products by harnessing the treasure of the human microbiota generating innovative solutions that enable to address unmet challenges in human ...
Manufactured by:Xenobiotic Detection Systems International, Inc. based inDurham, NORTH CAROLINA (USA)
The Ah receptor (AhR) is a ligand-activated transcription factor that mediates the induction or inhibition of expression of a diverse spectrum of genes resulting in a ligand-specific spectrum of biological and/or toxicological effects. The AhR also has been shown to play a key regulatory role in endogenous physiological responses as well as human disease and it ...
Manufactured by:Caprico Biotechnologies, Inc. (CBI) based inNorcross, GEORGIA (US) (USA)
EAPII has been demonstrated to have promiscuous protein associations, broad responsiveness to various extracellular signals, and pleiotropic functions in the development of human diseases including cancer and neurodegenerative ...
Manufactured by:Quidel Corporation based inSan Diego, CALIFORNIA (USA)
Bordetella is a family of small gram-negative bacterial pathogens that cause respiratory tract infections in humans and animals.1 Nine species of Bordetella have been identified to date, but Bordetella pertussis causes most of the human disease and only three additional members, B. bronchiseptica, B. parapertussis, and B. holmesii have been ...
Manufactured by:AllCells based inAlameda, CALIFORNIA (USA)
CD34+ HSPCs can be isolated from mobilized peripheral blood, bone marrow, and umbilical cord blood. Clinical HSPC transplantation is used to treat blood cancers (leukemia, myeloma and lymphomas), autoimmune diseases, and more. Gene-modified HSPCs (in vivo or ex vivo) are a promising new modality for a growing number of human diseases including ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Protectin D1 also serves as a specialized pro-resolving mediator, exhibiting effective in vivo pro-resolving activity in various human disease models. Additionally, Protectin D1 is an inhibitor of NALP3 inflammasomes and regulates the PI3K/AKT and HIF-1α signaling pathways. Protectin D1 exerts anti-inflammatory effects by reducing ROS levels, inhibiting the ...
Manufactured by:Advanced Electrophoresis Solutions Ltd. (AES) based inCambridge, ONTARIO (CANADA)
With our ISO:9001 certification, AES is proud to offer a comprehensive range of critical consumables, including proprietary cartridges, ampholytes, pI markers, electrolytes, and general solutions and consumables. In particular, we are pleased to supply high-quality 0.5% and 1% Methyl Cellulose (MC) solutions for icIEF analysis. Our MC solutions are fast, long-lasting, and compatible with ...
Manufactured by:Bayer AG based inLeverkusen, GERMANY
Small molecules (SMOLs) have long been in the focus of modern medicine. Over the last century, their advent revolutionized healthcare and improved the lives of patients all over the world. Most of today´s SMOLs exert their function by binding to proteins, thereby modulating their ability to catalyze biochemical reactions. However, a lot of proteins are difficult targets for SMOLs, since ...
Manufactured by:Singleron Biotechnologies GmbH based inKöln, GERMANY
Single-cell RNA technologies have rarely been adapted to microorganisms because of challenges related to their size, lower RNA content within a single cell and strict lysis requirements. Singleron developed the first commercially available product to enable high throughput single-cell RNA-Seq from yeast models. This novel technology enables researchers, pathologists, food industries and ...
Manufactured by:Auro Vaccines LLC based inPearl River, NEW YORK (USA)
As part of its comprehensive Public Health and Biodefense vaccine franchise, under a license from the Henry M. Jackson Foundation, Auro Vaccines is developing a subunit vaccine (HeV-sG-V) composed of the envelope glycoprotein of Hendra virus for the prevention of Nipah virus (NiV) ...
Manufactured by:Aidar Health based inBaltimore, MARYLAND (USA)
MouthLab is a non-invasive, hand-held. Rapid Health Assessment device that is designed to be used at home. It is cost-effective and as easy to use as a digital thermometer, yet capable of measuring multiple vital health parameters in under 80 ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Azaindoles and their derivatives exhibit significant biological activities, hence they are widely concerned in terms of drug optimization strategies. The four azaindole positional isomers, which associate a pyridine and a pyrrole ring by a fused C-C bond, possess all of the criteria necessary to be excellent bioisosteres of the indole or purine systems. The physicochemical and pharmacological ...
Manufactured by:Aelan Cell Technologies based inSan Francisco, CALIFORNIA (USA)
Adult stem cells have been shown to possess a broad spectrum of immunoregulatory capabilities. They affect both adaptive and innate immunity by secretion of growth factors, chemokines and regulators that promote organ and tissue homeostasis by inducing cell proliferation, angiogenesis, interactions with the immune system and protection against cell ...
Manufactured by:Belchem Industries (India) Pvt. Ltd. based inMUMBAI, INDIA
It finds extensive use as an alternative to parabens in cosmetic preparations since parabens have been time and again, identified as a source of several critical diseases in ...
Manufactured by:SIGA Technologies, Inc. based inNew York, NEW YORK (USA)
Oral TPOXX® (tecovirimat) is the first drug approved by the U.S. Food and Drug Administration (FDA) that is specifically indicated for the treatment of smallpox disease in adults and pediatric patients weighing at least 13 kg. (Prescription Label) TPOXX® inhibits viral maturation of variola virus (the virus that causes smallpox) and other poxviruses by preventing the formation of a ...