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Immune Activity Equipment & Supplies

81 equipment items found

Model OGB23501 - Tri-Specific Tumor Microenvironment (TME)

Model OGB23501 - Tri-Specific Tumor Microenvironment (TME)

by:Onegene Biotechnology   based inSuwon, SOUTH KOREA
OGB23501 is a first-in-class tri-specific tumor microenvironment (TME) immune activator, which simultaneously targets PD-1, CTLA-4, and VEGF. We aim to develop it as a potential backbone therapy for melanoma, NSCLC, HCC, and renal ...
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Model OSE-127/ S95011 - Humanized Monoclonal Antibody

Model OSE-127/ S95011 - Humanized Monoclonal Antibody

Manufactured by:OSE Immunotherapeutics   based inNantes, FRANCE
A humanized monoclonal antibody, is an antagonist of the alpha chain of the interleukine-7 receptor, CD127, present on T effector cells, thus down regulating the immune activity. Interleukin-7 (IL-7) is a cytokine that controls the proliferation, apoptosis and activation of CD4 and CD8 effector T-cells in ...
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Off-the-Shelf Natural Killer (NK) Cells for Oncology

Off-the-Shelf Natural Killer (NK) Cells for Oncology

Manufactured by:Senti Biosciences   based inSouth San Francisco, CALIFORNIA (USA)
Natural Killer (NK) cells are essential components of the immune system, playing an important role in the body’s defensive response against tumors and infected cells. NK cells constantly patrol the body to detect and neutralize foreign cells. Senti Bio believes there are several advantages that NK cells confer in relation to other potential immune cell ...
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Stemline - Model SL-701 - Immunotherapy

Stemline - Model SL-701 - Immunotherapy

by:Stemline Therapeutics, Inc.   based inNew York, NEW YORK (USA)
SL-701 is an immunotherapy designed to direct the immune system to attack targets present on certain malignancies including brain cancer. SL-701 comprises 3 short synthetic peptides that correspond to epitopes of targets including IL-13Rα2, EphA2, and survivin; 2 of these synthetic peptides (IL-13Rα2 and survivin) are mutant and believed to enhance ...
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T-cell Proliferation & Cytokine Analysis

T-cell Proliferation & Cytokine Analysis

Manufactured by:Alcyomics Ltd.   based inNewcastle Upon Tyne, UNITED KINGDOM
Assessment of immune activation: Alcyomics has a wide range of cell phenotypic services for your research needs, to benefit both drug discovery and validation. With our in-house state-of-the-art instrumentation, we can analyse and deliver accurate analyses of T-cell proliferation responses and perform multiplex cytokine analysis. This screening test can be used ...
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MedChemExpress - Model Tesnatilimab - 2242758-08-1

MedChemExpress - Model Tesnatilimab - 2242758-08-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tesnatilimab is a human IgG4 monoclonal antibody that acts on the immune activating receptor NKG2D and has potential immunomodulatory and anti-inflammatory activity. Tesnatilimab can be used in the study of inflammatory bowel disease ...
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Sumitomo - Immunotherapeutic Cancer Vaccines

Sumitomo - Immunotherapeutic Cancer Vaccines

by:Sumitomo Pharma Oncology, Inc.   based inCambridge, MASSACHUSETTS (USA)
Immunotherapeutic cancer vaccines have generated a lot of interest from oncologists since it was discovered that immune activation can lead to a specific antitumor response.1 However, despite initial progress, most cancer vaccines have failed to drive sufficient tumor immunogenicity, leading to poor clinical responses.1 The reason for this may be that previous ...
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Model ES014 - Anti-CD39xTGF-ß BsAb Dual-Acting Molecule

Model ES014 - Anti-CD39xTGF-ß BsAb Dual-Acting Molecule

Manufactured by:Elpiscience   based inShanghai, CHINA
ES014 is a first-in-class anti-CD39xTGF-β bispecific antibody (bsAb) that simultaneously targets the adenosine and TGF-β pathways, two major immunosuppressive mechanisms in the tumor microenvironment (TME). Solid tumors frequently express TGF-β, which suppresses T cell activation and induces CD39 expression, the rate-limiting enzyme in the ATP-adenosine pathway. ...
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MedChemExpress - Model Histamine dihydrochloride - 56-92-8

MedChemExpress - Model Histamine dihydrochloride - 56-92-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Histamine dihydrochloride is a reactive oxygen species (ROS) inhibitor. Histamine dihydrochloride can suppress ROS production and work together with IL-2 to activate T cells and NK cells, leading to immune activation in the tumor microenvironment, which consequently kills acute myeloid leukemia (AML) cells. Histamine dihydrochloride can cause a ...
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Vaxchora - Cholera Vaccine

Vaxchora - Cholera Vaccine

Manufactured by:Emergent BioSolutions Inc.   based inGaithersburg, MARYLAND (USA)
VAXCHORA is a vaccine indicated for active immunization against disease caused by Vibrio cholerae serogroup O1 in adults 18 through 64 years of age traveling to cholera-affected ...
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multimmune - Model ENKASTIM - Natural Killer (NK) Cells

multimmune - Model ENKASTIM - Natural Killer (NK) Cells

Manufactured by:multimmune GmbH   based inMunich, GERMANY
ENKASTIM is based on the activation of immune cells called natural killer (NK) cells that are major players in the body's first line of defense, also called innate immunity. The immune effector cells are activated ex vivo (outside the body; ENKASTIM-ev) or in vivo (inside the body; ...
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Virbac RABIGEN - Model Mono - Recommended Vaccine

Virbac RABIGEN - Model Mono - Recommended Vaccine

Manufactured by:Virbac Animal Health India Pvt. Ltd.   based inMumbai, INDIA
Virbac's RABIGEN Mono is a single-strain, killed vaccine indicated for the prevention of Rabies. RECOMMENDED FOR Active immunization of dogs and cats against ...
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Novavax - Model GP - Glycoprotein Vaccine

Novavax - Model GP - Glycoprotein Vaccine

Manufactured by:Novavax   based inGaithersburg, MARYLAND (USA)
In 5 separate studies, carried out in collaboration with the National Institute of Allergy and Infectious Diseases, active immunization with the Ebola GP vaccine was shown to be highly immunogenic and efficacious in preventing lethal disease in non-human primates challenged with EBOV. Our 2015 Phase 1 clinical trial demonstrated that our Ebola GP vaccine is ...
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Genome Editing with CRISPR-Cas9

Genome Editing with CRISPR-Cas9

Manufactured by:Integrated DNA Technologies, Inc.   based inCoralville, IOWA (USA)
The Alt-R CRISPR-Cas9 System includes all of the reagents needed for successful genome editing based on the natural S. pyogenes CRISPR-Cas9 system. Discover what makes the Alt-R CRISPR-Cas9 system best in ...
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Mai Fu Tong - Hydatid Powder

Mai Fu Tong - Hydatid Powder

Manufactured by:Newgen Biotech(Ningbo) Co.,Ltd   based inXiangshan County, CHINA
Product formula: Hydatid powder (addition amount 87.2%, containing β-glucan), Luo Han Guo powder, yam powder, hawthorn powder, Bifidobacterium lactis, R. rhamnosus, yeast β-glucan, oat-β- Glucan. Product specifications: 5g * 20 / box. How to eat: Take it directly or take it with water below 37 ...
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Arenavirus-Based Therapies Technology

Arenavirus-Based Therapies Technology

by:Hookipa Pharma Inc.   based inVienna, AUSTRIA
Our scientific platform includes two distinct approaches to arenavirus-based therapies: replicating and non-replicating. Our replicating technology is designed to create a stronger immune response that we believe is more appropriate for use in oncology. Our non-replicating technology is designed to evoke a potent immune response for prophylactic use against infectious disease. ...
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Cancer Vaccines

Cancer Vaccines

Manufactured by:Virometix AG   based inSchlieren, SWITZERLAND
Effective antigen delivery and a strong and durable response is the basis for successful cancer vaccines. The SVLP approach, with its modular and flexible design, the inherent adjuvant properties and other immune system activators, lends itself to the development of particle-based vaccines against cancer: SVLPs displaying cancer antigens are optimally presented ...
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SystImmune - Model SI-B003 - Tetravalent

SystImmune - Model SI-B003 - Tetravalent

Manufactured by:SystImmune Inc.   based inRedmond, WASHINGTON (USA)
By combining bi-valency with bi-specificity in the tetravalent format, the dual checkpoint molecule utilizes avidity and bi-specificity to improve anti-cancer immune cell function. The specificity enhancement both synergistically enhance and expand the breadth of immune cell activity that is diminished in cancer patients (SEBA). The ...
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FUSIX Technology

FUSIX Technology

by:Fusix Biotech   based inMünchen, GERMANY
This results in an oncolytic virus platform with an excellent safety profile and effective replication kinetics. Tumor-selective replication leads to significant oncolytic activity, while fusion-based cell death adds to its potent immune-stimulatory properties. Together this results in tumor regression and systemic tumor-specific immunity. ...
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BriaCell - Model Bria-IMT - Immunotherapy

BriaCell - Model Bria-IMT - Immunotherapy

Manufactured by:BriaCell Therapeutics Corp.   based inWest Vancouver, BRITISH COLUMBIA (CANADA)
Bria-IMT™ (developed from a breast cancer cell line) is a patented (USPTO) immunotherapy approach that directly stimulates the body’s own cancer fighting cells to attack and destroy breast cancer tumors. ...
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