Immune Cell Equipment
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Manufactured by Biosceptre International Limitedbased in UNITED KINGDOM
nfP2X7 is a tumour-specific form of the P2X7 ligand-gated ion channel, consisting of three identical protein subunits. When exposed to high concentrations of extracellular adenosine triphosphate (ATP), P2X7 forms a channel, driving a range of diverse physiological functions including proliferation and immune cell functions. Under ...
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based in USA
Alpha-1 Biologics has developed orally-available small molecules including our lead molecule, Alpha-101. We have shown that Alpha-101 is safe and effective in mice for increasing immune cells. When combined with the PD-1 immune checkpoint inhibitor, Alpha-101 significantly decreases the growth of kidney tumors in mice. ...
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Manufactured by Bio-Technebased in USA
Immune cell therapy is rapidly emerging as an important alternative for cancer treatment, as well as treatment of autoimmune disease. Also known as adoptive cell therapy or cellular immunotherapy, it supercharges an individual’s immune cells to fight disease. ...
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Manufactured by Advanced Cellular Dynamics, Inc. (ADC)based in USA
Our catalog of primary immune effector cells derive from whole blood obtained from anonymous donors. Individual subsets are affinity purified by negative selection when possible, or positive selection when necessary. The methods deployed are disclosed within the specification data so that you can decide if the process used might adversely ...
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based in CANADA
mutations to the CH2 domain of the antibody's Fc region to selectively modulate an antibody’s interactions with the Fc-gamma receptors (FcgR) expressed on the surface of immune cells and with a component of the complement pathway (i.e. C1q). ...
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Manufactured by Promega Corporationbased in USA
The antibodies used to stimulate T cell activation via interaction with co-stimulatory receptors on the effector cells can be cross-linked via binding to FcγRIIb receptors on CHO-K1 cells. Based on the properties of the antibody tested, the Co-Stimulatory Immune Checkpoint (i.e., OX40, CD40, GITR and 4-1BB) bioassays can ...
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Manufactured by Promega Corporationbased in USA
4-1BB (CD137/TNFRSF9), a member of the tumor necrosis factor receptor superfamily, is an inducible co-stimulatory receptor expressed on T cells, natural killer (NK) cells and innate immune cell populations. When present on the cell surface, 4-1BB interacts with 4-1BB ligand (4-1BBL) and induces subsequent ...
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Manufactured by 10x Genomicsbased in USA
Multiomic profiling of immune diversity, cell by cell. Chromium Single Cell Immune Profiling provides a multiomic solution to your immunology questions. Analyze full-length, paired B-cell or T-cell receptors, surface protein expression, antigen specificity, and gene expression, ...
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Manufactured by Regeneron Pharmaceuticals Inc.based in USA
VelociHum is our immunodeficient mouse platform that can be used to accurately test human therapeutics against human immune cells and to study human tumor models. Through genetic humanizations, VelociHum mice have been optimized to allow for better development of human immune cells in vivo, as well as to allow for engraftment of ...
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Manufactured by Synaffix BVbased in NETHERLANDS
Enabling immune cell engagers & other protein ...
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Manufactured by multimmune GmbHbased in GERMANY
ENKASTIM is based on the activation of immune cells called natural killer (NK) cells that are major players in the body's first line of defense, also called innate immunity. The immune effector cells are activated ex vivo (outside the body; ENKASTIM-ev) or in vivo (inside the body; ...
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Manufactured by Second Genome Therapeuticsbased in USA
SG-3-06686 binds to CXCR3 receptor on dendritic cells, amplifies the natural ligand which induces a robust immune cell migration to the tumor microenvironment, ultimately resulting in tumor shrinkage. ...
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Manufactured by SystImmune Inc.based in USA
Guidance and Navigation Control (GNC) molecules are multi-specific cell engager proteins. GNC in the oncology therapeutics class bind to cancer cells and to immune cells and stimulate the immune cell cancer killing activity. By design, each GNC molecule is multi-function. In the process of ...
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Manufactured by Tactiva Therapeuticsbased in USA
Adoptive Cell Transfer (ACT) is a form of immunotherapy that targets tumors specifically and potently by utilizing large numbers of a patient’s own immune cells to target and destroy cancer cells. Typically, starting with a few immune cells derived from the patient’s blood, ...
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Manufactured by Senti Biosciencesbased in USA
The product profile of SENTI-301 has the potential to promote expansion and persistence of NK cells, and activate and recruit the body’s own immune cells into the solid tumor microenvironment for enhanced anti-tumor activity. ...
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Manufactured by Akoya Biosciencesbased in USA
Unraveling the complex and dynamic tumor microenvironment requires the assessment of spatial relationships between tumor and immune cells. Multiplex imaging utilizing tumor and immunologic markers can reveal the spatial relationships between tumor and immune cells, leading to the discovery of spatial signatures, a new class ...
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Manufactured by SystImmune Inc.based in USA
Guidance and Navigation Control (GNC) molecules are multi-specific cell engager proteins. GNC in the oncology therapeutics class bind to cancer cells and to immune cells and stimulate the immune cell cancer killing activity. By design, each GNC molecule is multi-function. In the process of ...
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Manufactured by SystImmune Inc.based in USA
Guidance and Navigation Control (GNC) molecules are multi-specific cell engager proteins. GNC in the oncology therapeutics class bind to cancer cells and to immune cells and stimulate the immune cell cancer killing activity. By design, each GNC molecule is multi-function. In the process of ...
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Manufactured by SystImmune Inc.based in USA
By combining bi-valency with bi-specificity in the tetravalent format, the dual checkpoint molecule utilizes avidity and bi-specificity to improve anti-cancer immune cell function. The specificity enhancement both synergistically enhance and expand the breadth of immune cell activity that is diminished in cancer patients (SEBA). ...
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Manufactured by BioLegend, Inc.based in USA
The TotalSeq™-A Human TBNK Cocktail has been designed to react with immune cells as defined and classified by the expression of the surface antigens CD19, CD3, CD16, CD4, CD11c, CD56 (NCAM), CD14, CD8, ...
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