Immune Suppressing Equipment
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based in USA
The SERT-CELL program explores the unique potential of Sertoli cells, protein-rich cells found in the mammalian testes, which inhibit immune reactions to foreign tissues, including transplants. Sertoli cells provide localized immunosuppression, which mitigates the need for a patient to undergo costly and potentially dangerous immune ...
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based in USA
and avoid the need for chronic and systemic immune suppression. ...
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Manufactured by Scopus BioPharmabased in USA
Our licensed gene therapy, CO-sTiRNA™, is a dual-action STAT3 inhibitor. STAT3 is a gene that drives tumor cell growth and anti-tumor immune suppression. CO-sTiRNA™ is a highly selective and targeted gene therapy that silences the activity of the STAT3 gene by way of RNA interference. CO-sTiRNA™ also stimulates TLR9 ...
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Manufactured by Elpisciencebased in CHINA
ES104 is a bispecific antibody that simultaneously blocks Delta-like ligand 4/Notch (DLL4) and vascular endothelial growth factor A (VEGF-A) signaling pathways, which are critical to angiogenesis and tumor vascularization. VEGF also plays an important role in creating an immune suppressive TME. Pre-clinical and early clinical data of ES104 ...
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Manufactured by Brooklyn ImmunoTherapeutics (BTX)based in USA
have discovered methods of suppressing innate immunity, which enable frequent transfection with protein-encoding RNA. ...
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Manufactured by Prima Lab SAbased in SWITZERLAND
Rapid self-test for the qualitative detection of antibodies against human immunodeficiency virus 1 and 2 (HIV1/HIV2) in whole blood. Human immunodeficiency virus, or HIV, is a pathogen that attacks and suppresses the immune system by specifically affecting white blood cells. The virus can be transmitted (a) sexually – through unprotected ...
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Manufactured by AVEO Pharmaceuticals, Inc.based in USA
that a pro-inflammatory state may be responsible for many of the symptoms associated with cachexia, a complex metabolic syndrome characterized by malnutrition and severe involuntary weight loss due to the loss of muscle and fat tissue, as well as the clinical manifestation of anemia, inflammation and suppression of immune ...
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Manufactured by Ibio, Inc.based in USA
T cells [Tregs] proliferate and suppress the immune responses to tumor cells. The Treg is a type of T cell that is important in preventing autoimmunity by keeping effector T cells [Teffs] “in-check” to prevent destruction of healthy tissues. However, around tumors, Tregs create an immunosuppressive environment and block the ...
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Manufactured by Jubilant Therapeutics Inc.based in USA
Strong scientific and clinical rationale for PAD4 inhibitors in autoimmune ...
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based in USA
Novel IL-2 approaches and technologies are driving innovation in the therapeutic development space. The IL-2 pathway influences critical aspects of both immune stimulation and immune regulation, through the development and expansion of regulatory T cells ...
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Manufactured by Bioplastics Internationalbased in USA
Many chemical additives that give plastic products desirable performance properties also have negative environmental and human health ...
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Manufactured by Immune-Onc Therapeutics, Inc.based in USA
Immune-Onc is evaluating IO-108, an antagonist antibody targeting the myeloid checkpoint, LILRB2 (also known as ILT4). The U.S. FDA has cleared the IND application for IO-108 as a potential therapy for solid tumors. The company expects to begin clinical trials with IO-108 in the second half of ...
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Manufactured by Immune-Onc Therapeutics, Inc.based in USA
Immune-Onc is evaluating IO-106, an antagonist antibody targeting LAIR1, an immune inhibitory receptor. The company’s preclinical research supports the proposed mechanisms of action of IO-106 and its evaluation as a potential treatment for solid ...
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Manufactured by DxTerity Diagnostics Inc.based in USA
The DxTerity Immunity Assessment Test measures COVID-19 neutralizing antibody levels from a small sample of blood. Knowing your neutralizing antibody levels can help you assess your risk of future symptomatic ...
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Manufactured by NightHawk Biosciencesbased in USA
HS-130: The First Allogeneic, Off-the-Shelf Cell Therapy that Delivers Localized OX40-mediated Co-Stimulation to Enhance T-cell Activation in Lung Cancer (NSCLC). HS-130 is designed to enhance the gp96 platform by facilitating antigen-driven T-cell activation and OX40L co-stimulation in a single product. The T-cell co-stimulatory fusion protein OX40L-Ig has the potential to combine with other ...
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based in SOUTH KOREA
Promotes the generation of cancer-specific effector T cell (Teff) in lymph nodes, and induces the activation and proliferation of tumor-infiltrating Teff and NK cells. Controls the immuno-suppressive function of regulatory T cells (Tregs) in tumor microenvironment (TME). Restores T cell function and anti-cancer immune responses in TME. Secures ...
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Manufactured by Cabaletta Bio, Inc.based in USA
the pathogenic autoantibodies while preserving the healthy B cells critical to immune function. We anticipate that much of what we learn from our DSG3-CAART program, including clinical trial design in the DesCAARTesTM trial, will inform and potentially accelerate the development of ...
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Manufactured by Jubilant Therapeutics Inc.based in USA
Strong scientific and clinical rationale for LSD1/HDAC6 inhibition in haematological and solid ...
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Manufactured by Elpisciencebased in CHINA
ES009: A Potential Best-in-Class Antibody Targeting LILRB2. ES009 is a potential best-in-class monoclonal antibody targeting LILRB2 designed to reprogram inhibitory myeloid cells to create an immune favorable TME. LILRB2 is an inhibitory receptor that suppresses myeloid cell activation. Blocking LILRB2 reverses immunosuppression by ...
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based in USA
TP-1454 is an investigational oral pyruvate kinase M2 isoform (PKM2) activator.44 This activation is thought to starve cancer cells of important molecular building blocks, inhibiting tumor cell proliferation, and enhancing antitumor ...
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