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Immune Tolerance Equipment & Supplies
12 equipment items found
by:Cartesian Therapeutics based inGaithersburg, MASSACHUSETTS (USA)
Selecta Biosciences’ immune tolerance platform, ImmTOR, is designed to give rise to antigen-specific immunity, mitigating unwanted immune ...
Manufactured by:eTheRNA based inNiel, BELGIUM
Therapeutic area: auto-immune diseases; Induction of immune tolerance against ...
Manufactured by:Brenus Pharma based inIssoire, FRANCE
An allogeneic first in class immunotherapy harnessing the patient immune system to fight immune tolerance and prevent cancer ...
Manufactured by:OncoVITA based inParis, FRANCE
Oncolytic viruses are replicative viruses that preferentially infect tumor cells while preserving healthy cells. Some of them, in particular the measles virus, exhibit immuno-adjuvant properties that reinforce the antitumor immune response by breaking immune tolerance to the ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
GSK547 (GSK'547) is a highly selective and potent inhibitor of receptor-interacting serine/threonine protein kinase 1 (RIPK1), inhibits macrophage-mediated adaptive immune tolerance in pancreatic ...
by:Vaxxinit based inDallas, TEXAS (USA)
Our Vaxxine Platform is designed to harness the immune system to convert the body into its own natural “drug factory” stimulating the production of antibodies. Our technology uses synthetic peptides to mimic and optimally combine biological epitopes to selectively activate the immune system and overcome “immune ...
Manufactured by:Toleris Biotherapeutics GmbH based inWürzburg, GERMANY
AIM Bio has developed a platform of Autoimmunity Modifying Biologicals (AIM Biologicals) that uses soluble, near-physiological proteins to induce selective, antigen-specific immune tolerance. These proteins mimic a natural process observed in pregnancy that protects the embryo from the maternal immune system. By leveraging optimized soluble ...
by:Cartesian Therapeutics based inGaithersburg, MASSACHUSETTS (USA)
ImmTOR has significant potential to mitigate unwanted immune responses and induce AAV-specific tolerance to enable redosing of gene therapies. ImmTOR has the potential to administer multiple low doses to achieve therapeutic benefit without risk of overdosing, the ability to treat patients typically excluded from these treatments and is a novel approach to ...
by:Fusix Biotech based inMünchen, GERMANY
The FUSIX Technology relies on a fusion-based oncolytic virus platform. Below you can see FUB101 in action. In this timelapse video FUB101 is killing a monolayer of cancer cells (HCC) within 48 hours through a fusogenic mechanism of action. The FUSIX technology is based on a hybrid virus construct combining all the advantages of both parental platforms while minimizing risks factors. This ...
by:Cartesian Therapeutics based inGaithersburg, MASSACHUSETTS (USA)
The current standard of care for autoimmune diseases is broad immunosuppression, which is associated with side effects and leaves patients vulnerable to serious infection and maligancies. Our approach to autoimmune disease is designed to restore natural self-tolerance by administering ImmTOR with nanoparticles-encapsulated self-antigens and avoid the need for chronic and ...
Manufactured by:Immune-Onc Therapeutics, Inc. based inPalo Alto, CALIFORNIA (USA)
Immune-Onc’s lead program is IO-202, an antagonist antibody targeting the myeloid checkpoint LILRB4 (also known as ILT3). Immune-Onc has a Phase I trial underway to evaluate IO-202 as a potential treatment for acute myeloid leukemia (AML) and chronic myelomonocytic leukemia ...
Manufactured by:Scopus BioPharma based inNew York, NEW YORK (USA)
Our licensed gene therapy, CO-sTiRNA™, is a dual-action STAT3 inhibitor. STAT3 is a gene that drives tumor cell growth and anti-tumor immune suppression. CO-sTiRNA™ is a highly selective and targeted gene therapy that silences the activity of the STAT3 gene by way of RNA interference. CO-sTiRNA™ also stimulates TLR9 receptors to activate the body’s immune defense to ...