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Immunosuppression Equipment & Supplies
90 equipment items found
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor ofmTORC1. Rapamycin is anautophagy activator, an ...
Manufactured by:Scandinavian Biopharma based inSolna, SWEDEN
Grafalon contains anti-human T-lymphocyte immunoglobulin from rabbits and belongs to a group of medicines called immunosuppressants. Immunosuppressants are used to prevent the body from rejecting transplanted ...
Manufactured by:Creative Peptides based inNew York, NEW YORK (USA)
Everolimus is a Kinase Inhibitor and mTOR Inhibitor Immunosuppressant. The mechanism of action of everolimus is as a Protein Kinase Inhibitor and Cytochrome P450 3A4 Inhibitor and P-Glycoprotein Inhibitor and Cytochrome P450 2D6 Inhibitor and mTOR Inhibitor. The physiologic effect of everolimus is by means of Decreased Immunologic Activity. ...
Manufactured by:Exscientia based inOxford, UNITED KINGDOM
EXS21546 is our peripherally-restricted and selective antagonist of the Adenosine A2a Receptor. It is designed for anti-cancer immunotherapy, combatting adenosine related immunosuppressive effects, through T-cell ...
Manufactured by:Kiadis Pharma NV based inAmsterdam, NETHERLANDS
Alomfilimab SAR445256 (formerly KY1044) is a human monoclonal IgG1 that selectively binds to Inducible T cell CO-stimulator (ICOS), a protein expressed at high levels on immunosuppressive regulatory T cells and at lower levels on effector T cells. Alomfilimab is designed to exert anti-tumour activity through preferential depletion of intra-tumoral regulatory T cells and ...
by:Saneron CCEL Therapeutics, Inc. based inTampa, FLORIDA (USA)
The SERT-CELL program explores the unique potential of Sertoli cells, protein-rich cells found in the mammalian testes, which inhibit immune reactions to foreign tissues, including transplants. Sertoli cells provide localized immunosuppression, which mitigates the need for a patient to undergo costly and potentially dangerous immune suppression, while the therapy is in effect. ...
by:Aegle Therapeutics based inWoburn, MASSACHUSETTS (USA)
Advancement of extracellular vesicle therapy to the patient has been hampered by an inability to isolate extracellular vesicles in useful quantities while preserving their structural and functional integrity. EVs derived from MSCs enjoy the same immunosuppressant characteristics of their parent cells. However, when EVs are processed incorrectly, they can trigger an adverse ...
Manufactured by:ELITechGroup based inPuteaux, FRANCE
PCP a major cause of morbidity and mortality among HIV-infected patient, nowadays reduced with ART, moreover, represents a significant cause of increasing mortality among HIV-negative patients who are immunosuppressed. For non-immunosuppressed individuals fungal invasion usually leads to asymptomatic colonization. Without treatment, PCP can cause death. Prompt ...
Manufactured by:Athelas Incorporated based inMountain View, CALIFORNIA (USA)
This FDA-cleared device helps simplify and enhance the blood monitoring process for those prescribed clozapine and other immunosuppressed patients. Getting a simple, onsite finger-prick is easy, eliminates the need for a venous draw, and the device returns neutrophil and white blood cell count within minutes. ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES014 is a first-in-class anti-CD39xTGF-β bispecific antibody (bsAb) that simultaneously targets the adenosine and TGF-β pathways, two major immunosuppressive mechanisms in the tumor microenvironment (TME). Solid tumors frequently express TGF-β, which suppresses T cell activation and induces CD39 expression, the rate-limiting enzyme in the ATP-adenosine pathway. ...
Manufactured by:Porkka Finland based inHOLLOLA, FINLAND
The ice cubes are produced using a spray system that minimizes water and power consumption, resulting in clear and hard ice cubes ideal for patient comfort, particularly for immunosuppressed individuals. The ice flakes are generated in a cylinder with a crushing screw, ensuring the production of dry, loose ice flakes that are easy to handle and store over long periods. These ...
Manufactured by:Ring Bioscience Technologies Ltd based inBeijing, CHINA
Bovine viral diarrhea (BVD) is a significant economic disease of cattle that is endemic in the majority of countries throughout the world. BVD infection results in a wide variety of clinical signs, due to its immunosuppressive effects,as well as having a direct effect on respiratory disease and fertility. In addition, BVD infection of a susceptible dam during a certain period of ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a ...
by:Cartesian Therapeutics based inGaithersburg, MASSACHUSETTS (USA)
The current standard of care for autoimmune diseases is broad immunosuppression, which is associated with side effects and leaves patients vulnerable to serious infection and maligancies. Our approach to autoimmune disease is designed to restore natural self-tolerance by administering ImmTOR with nanoparticles-encapsulated self-antigens and avoid the need for chronic and ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Methylprednisolone succinate (Methylprednisolone hydrogen succinate) sodium, a glucocorticoid, is a immunosuppressive agent with anti-inflammatory ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Tucotuzumab (Anti-EPCAM Recombinant Antibody) is an antigen-specific IgG1 monoclonal antibody that targets human epithelial cell adhesion molecule (EpCAM). Tucotuzumab links two IL-2 molecules and is an immunosuppressant and anti-tumor active ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Betamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone accelerates fetal lung maturation and induces gene expression and ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Busulfan causes DNA damage by cross-linking DNAs and DNA and proteins. Busulfan inhibits thioredoxin reductase. Busulfan induces apoptosis. Busulfan is an immunosuppressive and myeloablative chemotherapeutic ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Rubropunctatin, an orange azaphilone pigment, is isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice). Rubropunctatin has anti-inflammatory, immunosuppressive and antioxidative effects, and also exhibits anti-tumor ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Cintirorgon (LYC-55716) modulates gene expression of RORγ expressing T lymphocyte immune cells, resulting in enhanced effector function, as well as decreased immunosuppression, resulting in decreased tumor growth, and improved ...