Inflammatory Autoimmune Equipment & Supplies
18 equipment items found
Manufactured by:provitro AG based inBerlin, GERMANY
Cultures based on cell monolayers have the advantage of reducing tissue complexity to a minimum. However, the lack of normal physiological cell-matrix interactions leads the cell metabolism and gene expression towards a dedifferentiated state. Compared to a monolayer, three-dimensional cultures are associated with a higher cell density, and nutrient supply depends on diffusion through the ...
Manufactured by:Firalis Group based inHuningue, FRANCE
As part of the European IMI BT-Cure consortium followed by the H2020 RABIOPRED program launched in 2016, FIRALIS launches its proprietary assay for the identification of markers related to inflammatory-autoimmune ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
IDO2-IN-1 is an orally active and potent Indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with an IC50 value of 112 nM. IDO2-IN-1 can be used for inflammatory autoimmunity ...
by:Horizon Therapeutics plc based inSaint Kevin`s, IRELAND
Exclusive collaboration to develop novel, multi-specific fusion protein based therapies for autoimmune and inflammatory ...
Manufactured by:SHL Medical AG based inZug, SWITZERLAND
The establishment of the Molly platform signifies SHL’s commitment to further addressing the varying needs of our customers and their patients. Introduced in 2010, Molly is SHL’s first preconfigured autoinjector designed to help pharmaceutical companies reduce initial investments and expedite development ...
Manufactured by:2A Pharma ApS based inAalborg Øst, DENMARK
2A Pharma’s anti-autoimmune vaccine candidate has potential in a number of indications. The vaccine is currently being tested in a vitiligo model in collaboration with different ...
Manufactured by:Enterome based inParis, FRANCE
New generation of oral bioactives to treat inflammatory and autoimmune diseases. EndoMimicsTM are first-in-class orally available bioactives drugs based on proteins secreted by the gut bacteria that act like human hormones or cytokines. Enterome expects partnering to play a central in generating value from its EndoMimics pipeline. ...
by:F. Hoffmann-La Roche Ltd. based inBasel, SWITZERLAND
Actemra/RoActemra is approved in 116 countries for the treatment of rheumatoid arthritis (RA). It is also approved for the treatment of paediatric juvenile idiopathic arthritis (pJIA), systemic juvenile idiopathic arthritis (sJIA), giant cell arteritis (GCA) and CAR-T cell-induced cytokine release syndrome (CRS). Actemra/RoActemra is available in both subcutaneous (SC) and intravenous (IV) ...
Manufactured by:Kiadis Pharma NV based inAmsterdam, NETHERLANDS
Amlitelimab is designed to rebalance the immune system by blocking inappropriate activation and proliferation of ‘pro-inflammatory’ effector T cells and promoting expansion of ‘anti-inflammatory’ regulatory T cells, without broad suppression of the immune system. We believe this mechanism-of-action means Amlitelimab could be applicable to ...
Manufactured by:OSE Immunotherapeutics based inNantes, FRANCE
OSE-230 is an agonist antibody against ChemR23, also known as chemerin chemokine-like receptor 1 (CMKLR1), a G-protein coupled receptor (GPCR) expressed on myeloid immune cells known to modulate inflammation. Persistent inflammation is a characteristic feature of all chronic inflammatory or autoimmune diseases and if not controlled or resolved, it can lead to ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
CCR6 antagonist 1 is a CCR6 antagonist that inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Semapimod tetrahydrochloride inhibits p38 MAPK and nitric oxide production in macrophages. Semapimod tetrahydrochloride has potential in a variety of inflammatory and autoimmune ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Piclidenoson exhibits antiproliferative effect and induces apoptosis in different cancer cell types like melanoma, leukemia. Piclidenoson can be used for the research of autoimmune inflammatory diseases and ...
Manufactured by:Krishgen Biosystems based inMumbai, INDIA
Tumor necrosis factor alpha (TNF ±) is a multifunctional cytokine secreted primarily by macrophages, natural killer (NK) cells, and lymphocytes.The main function of TNF Alpha is to regulate the immune cells. It has the ability to induce a fever, speed up cell death, create inflammation etc. It stimulates the acute phase response on the liver, which can lead to a growing amount of ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
ERG240 is an oral active branched-chain amino acid aminotransferase 1 (BCAT1) inhibitor. ERG240 can be used for the research of cancer, rheumatoid arthritis, and bone ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Penfluridol (R-16341) is a potent, long-acting, first-generation, oral diphenylbutylpiperidine antipsychotic agent by targeting D2-like dopamine receptor. Penfluridol effectively inhibits TNFα-induced NF-κB activation and alleviates the severity of arthritis and colitis in vivo. Penfluridol is a Ca2+-calmodulin inhibitor. Penfluridol induces apoptosis and autophagy. Penfluridol is used for ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 µM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Infliximab prevents the interaction of TNF-α with TNF-α receptor (TNFR1 and TNFR2). Infliximab has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy ...