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Intestinal Barrier Equipment & Supplies

19 equipment items found

MedChemExpress - Model 3-Aminobenzoic acid - 99-05-8

MedChemExpress - Model 3-Aminobenzoic acid - 99-05-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
3-Aminobenzoic acid (3-ABA) is an orally active anti-inflammatory agent targeting the tight junction (TJ) regulatory pathways in intestinal epithelial cells. 3-Aminobenzoic acid improves intestinal inflammation by enhancing intestinal barrier integrity and reducing epithelial permeability. It can be used in studies related to ...
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MedChemExpress - Model Ursodeoxycholic acid - 128-13-2

MedChemExpress - Model Ursodeoxycholic acid - 128-13-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid ...
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OrganoReady - Model Colon Caco-2 - Human-Relevant, Complex 3D Tissue Models

OrganoReady - Model Colon Caco-2 - Human-Relevant, Complex 3D Tissue Models

Manufactured by:Mimetas B.V.   based inLeiden, NETHERLANDS
Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Colon Caco-2 you can now easily take your intestinal research to the next level. Perform your self-created experiments to investigate permeability, absorption and transport, toxicity, and ...
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Oramed - Oral Drug Delivery Technology

Oramed - Oral Drug Delivery Technology

Manufactured by:Oramed Pharmaceuticals, Inc.   based inNew York, NEW YORK (USA)
The attractive advantages of oral drug delivery, including increased patient comfort and compliance, reduced risk of infection, simpler application in pediatric medicine, first-pass metabolism preceding systemic exposure, and cost effectiveness, have positioned it the most popular and preferred route of drug ...
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Endotoxins - LPS Endotoxicity Modulator

Endotoxins - LPS Endotoxicity Modulator

Manufactured by:Nutrex   based inOlen, BELGIUM
Endotoxins are toxic compounds from bacterial origin. The most well-known endotoxins are lipopolysaccharides (LPS), which are part of the cell wall of Gram-negative bacteria (e.g. E. coli, Salmonella). LPS from all Gram-negative bacteria, commensal or pathogenic, share the same chemical structure, being an outer O-polysaccharide, an inner R-polysaccharide and a lipid A moiety. The latter ...
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Siolta - Model STMC-106 - Prevention of  Necrotize Entercolitis (NEC)

Siolta - Model STMC-106 - Prevention of Necrotize Entercolitis (NEC)

Manufactured by:Siolta Therapeutics   based inSan Carlos, CALIFORNIA (USA)
Necrotizing enterocolitis is a serious inflammatory disease of the bowel and the most common single cause of sepsis and death in preterm infants. NEC occurs primarily in infants born before 32 weeks gestation, with overall incidence inversely proportional to gestational age. Several additional risk factors for NEC, including initiation of enteral feeding, antibiotic treatment, and acid ...
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Emulate - Duodenum Intestine-Chip

Emulate - Duodenum Intestine-Chip

Manufactured by:Emulate   based inBoston, MASSACHUSETTS (USA)
Study drug absorption and drug-drug interactions in a primary organoid-based model of the human small ...
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Nutracid InteStim - Immune Modulating Supplement for Pig Growth

Nutracid InteStim - Immune Modulating Supplement for Pig Growth

Manufactured by:Nutrex   based inOlen, BELGIUM
Nutracid Intestim is an innovative product for pigs, that supports growth and improves feed conversion by modulating the immune system, stimulating villi growth and increasing absorption ...
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FiberStart - Model HP - Concept of Enzymatically Co-Processed Protein and Fiber Raw Materials

FiberStart - Model HP - Concept of Enzymatically Co-Processed Protein and Fiber Raw Materials

Manufactured by:Hamlet Protein A/S   based inHorsens, DENMARK
Use HP FiberStart instead of ZnO in nursery feed. HP FiberStart is a concept of enzymatically co-processed protein and fiber raw materials. The result is a functional ingredient, which contains fermentable fibers. The purpose is to stimulate the weaning pig in multiple ways. In addition HP FiberStart removes the need for Zinc oxide in nursery feed to promote firm feces and maintain the same ...
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OMNi-LOGiC - Model Plus - Precision Prebiotics for Metabolism and Energy

OMNi-LOGiC - Model Plus - Precision Prebiotics for Metabolism and Energy

Manufactured by:Omni-Biotic   based inPort Chester, NEW YORK (USA)
Combines valuable dietary fibers with important vitamins and minerals that serve as the food for essential, anaerobic probiotic bacteria, and promote intestinal health, strong gut barrier function as well as weight ...
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MedChemExpress - Model Flufenamic acid-13C6 - 1325559-30-5

MedChemExpress - Model Flufenamic acid-13C6 - 1325559-30-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Flufenamic acid-13C6 is the 13C6 labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both ...
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MedChemExpress - Model Tegoprazan - 942195-55-3

MedChemExpress - Model Tegoprazan - 942195-55-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tegoprazan inhibits gastric acid secretion and motility against porcine, canine and human H+/K+-ATPase with IC50 values ranging from 0.29-0.52 μM in vitro. Tegoprazan significantly improves colitis and enhances the intestinal epithelial barrier function in mice. Tegoprazan is promising for research of Inflammatory bowel, gastric acid-related, motilityimpaired ...
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Model LB1148 - Novel Oral Liquid Formulation

Model LB1148 - Novel Oral Liquid Formulation

Manufactured by:Palisade Bio   based inCarlsbad, CALIFORNIA (USA)
Our lead asset LB1148 is a novel oral liquid formulation of the well-characterized digestive enzyme inhibitor, tranexamic acid (“TXA”), with potential to both reduce abdominal adhesions and help restore bowel function following surgery. The therapy is being developed for administration prior to major surgeries that are at risk of disrupting the intestinal epithelial ...
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Emulate - Colon Intestine-Chip

Emulate - Colon Intestine-Chip

Manufactured by:Emulate   based inBoston, MASSACHUSETTS (USA)
Investigate mechanisms of colon inflammation and barrier disruption and evaluate the efficacy of anti-inflammatory drug candidates in an organoid-derived ...
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MedChemExpress - Model [6]-Gingerol - 23513-14-6

MedChemExpress - Model [6]-Gingerol - 23513-14-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and ...
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NuLivScience AstraGin - Enhances Nutrient

NuLivScience AstraGin - Enhances Nutrient

Manufactured by:NuLiv Science   based inBrea, CALIFORNIA (USA)
AstraGin restores gut wall integrity by triggering an anti-inflammatory response and activating the mTOR pathway for rapid intestinal stem cell migration and differentiation in the inflamed intestinal mucosal barrier (epithelial cell and tight junction). AstraGin promotes gut ecosystem homeostasis by the symbiotic effect of restoring gut wall ...
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MedChemExpress - Model 6PPD-Q - 2754428-18-5

MedChemExpress - Model 6PPD-Q - 2754428-18-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and ...
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MedChemExpress - Model Dextran sulfate sodium salt (MW 35000-45000) - 9011-18-1

MedChemExpress - Model Dextran sulfate sodium salt (MW 35000-45000) - 9011-18-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Dextran sulfate sodium salt (MW 35000-45000) is a polymer of anhydroglucose and is a potent inducer of colitis. Dextran sulfate sodium salt (MW 35000-45000) may be related to macrophage dysfunction, intestinal flora dysbiosis, and is particularly toxic to the colonic epithelium. Dextran sulfate sodium salt (MW 35000-45000) also inhibits human immunodeficiency virus replication by preventing viral ...
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MedChemExpress - Model Flufenamic acid - 530-78-9

MedChemExpress - Model Flufenamic acid - 530-78-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as ...
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