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Kidney Cell Equipment & Supplies
82 equipment items found
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Ciglitazone is a potent and selective PPARγ agonist (EC50=3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum ...
Manufactured by:KM Biologics Co. Ltd. based inKumamoto, JAPAN
A hepatitis A vaccine produced by culturing hepatitis A virus on African green monkey kidney GL37 cells, followed by purification and inactivation. Aimmugen was developed in Japan. It is lyophilized and contains no adjuvants. Aimmugen can be administered subcutaneously or intramuscularly to people of all ages. General immunization requires 3 administrations, ...
by:Expression Systems, LLC based inDavis, CALIFORNIA (USA)
Expression Systems offers 293 and CHO mammalian cell lines adapted to serum-free suspension culture in ESF SFM. The availability of pre-adapted cells saves significant time and expense associated with the adaptation of cultures. ...
Manufactured by:T-Cure BioScience, Inc. based inSherman Oaks, CALIFORNIA (USA)
The HERV-E target is one of the quiescent Human Endogenous Retro-Virus (HERV) sequences that are turned on during tumor development. Its expression in renal cell carcinoma (RCC) is highly selective, with no transcripts detected in any normal tissues. It is expressed in 85% of clear cell RCC (ccRCC). The TCR molecule was identified in a responding patient, following allogeneic stem cell therapy. ...
Manufactured by:BridgeBio Pharma, Inc. based inPalo Alto, CALIFORNIA (USA)
GPX4 neutralizes toxic free radicals at the lipid membrane, protecting cells from death by ferroptosis. BridgeBio is developing covalent inhibitors of GPX4 designed to induce ferroptosis in cancer cells. BridgeBio has entered into a strategic collaboration with Helsinn to co-develop and co-commercialize a potentially first-in-class inhibitor designed to target glutathione peroxidase 4 (GPX4) with ...
Manufactured by:Universal Cells Inc. based inSeattle, WASHINGTON (USA)
Combining class I and class II engineering to create Universal Donor Cells (UDCs) that are appropriate for developing numerous differentiated cell ...
Manufactured by:AMEGA Biotech based inOlivos, ARGENTINA
Interferons are a group of antiviral proteins produced in reaction to viral infections. It boosts the resistance of surrounding cells to attacks by viruses, inhibits viral multiplication and modifies the body’s immune response. Interferon alfa is the type that has been found to be most useful in the treatment of certain forms of cancer, including metastatic renal cell carcinoma and hairy ...
Manufactured by:Amicus Therapeutics, Inc. based inPhiladelphia, PENNSYLVANIA (USA)
Galafold® is indicated for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene (GLA) variant based on in vitro assay data. This indication is approved under accelerated approval based on reduction in kidney interstitial capillary cell globotriaosylceramide (KIC GL-3) substrate. Continued approval for ...
by:CIS Pharma AG based inBubendorf, SWITZERLAND
CIS Pharma develops novel antibody-drug- conjugates (ADCs) based on our proprietary polymer carrier platform. Our polymers serve as carriers that are loaded with cytotoxic drugs, radioisotopes or other active entities. The carrier together with its cargo is conjugated to a target-specific antibody using site-directed linker chemistry, different from the linker chemistry used to attach the ...
by:F. Hoffmann-La Roche Ltd. based inBasel, SWITZERLAND
Avastin is a monoclonal antibody that targets vascular endothelial growth factor A (VEGF-A). With the initial approval in the United States for advanced colorectal cancer in 2004, Avastin became the first anti-angiogenic therapy made widely available for the treatment of patients with an advanced ...
Manufactured by:Cabaletta Bio, Inc. based inPhiladelphia, PENNSYLVANIA (USA)
PLA2R-CAART is being developed to treat patients with PLA2R-associated membranous nephropathy (MN), a B cell-mediated autoimmune disease that affects the kidneys. B cells produce autoantibodies, which are believed to form immune complexes that are deposited at the glomerular basement membrane, causing damage of the filtration barrier, ...
Manufactured by:AMEGA Biotech based inOlivos, ARGENTINA
Interferons are a group of antiviral proteins produced in reaction to viral infections. It boosts the resistance of surrounding cells to attacks by viruses, inhibits viral multiplication and modifies the body’s immune response. Interferon alfa is the type that has been found to be most useful in the treatment of certain forms of cancer, including metastatic renal cell carcinoma and hairy ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Kidney proximal tubule cell model for safety/efficacy and transporter studies. aProximate™ is one of the most advanced, near physiological, in vitro, kidney proximal tubule cell (PTC) models. aProximate™ PTCs are derived from fresh human kidney tissue and grown on Transwells® where they remain as ...
Manufactured by:Celdara Medical, LLC based inLebanon, NEW HAMPSHIRE (USA)
Celdara Medical gives hope and health to patients by transforming academic innovations into medicines that cure the world’s most challenging ...
Manufactured by:TVAX Biomedical, Inc. based inOlathe, KANSAS (USA)
TVAX®’s second candidate (TVI-Kidney-1) is being evaluated for the treatment of kidney cancer and targets stage 4 renal cell ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Podocyte model for assessing glomerular toxicity. Newcells now offers the first fully differentiated, primary podocyte model derived from fresh kidney tissue for the in vitro assessment of drug-induced glomerular toxicity. The effect of a drug on the glomerular filtration barrier and podocyte glomerular permeability can now be easily evaluated in vitro. Podocyte injury and ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Evaluate drug candidate toxicity at clinically relevant concentrations in a co-culture human kidney model. Predicting drug-induced kidney toxicity and drug-drug interactions continues to be a challenge due to a reliance on immortalized cell line culture or animal models that do not translate to human response. The co-culture Emulate ...
Manufactured by:AVEO Pharmaceuticals, Inc. based inBoston, MASSACHUSETTS (USA)
FOTIVDA (tivozanib) is an oral, once-daily, differentiated vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor (TKI). It is a potent, selective inhibitor of VEGFRs 1, 2, and 3 with a long half-life designed to improve efficacy and tolerability.1,2 AVEO received U.S. Food and Drug Administration (FDA) approval for FOTIVDA in March 2021 for the treatment of adult patients ...
by:Osel Inc. based inMountain View, CALIFORNIA (USA)
CBM588 is an orally-administered Clostridium butyricum strain with a long history of clinical use and safety in all age groups in Japan. In Japan, CBM588 has primarily been used to treat infectious and noninfectious diarrheal disorders associated with dysbiosis of the human gastrointestinal microbiome. CBM588 inhibits certain enteric pathogens and supports colonic homeostasis by producing butyric ...
Manufactured by:Stanford Chemicals Company based inLake Forest, CALIFORNIA (USA)
Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. It was approved for medical use in the United States in 1955. It regulates the activity of the immune system and modifies the underlying disease process, rather than simply treating the symptoms. ...