Liver Toxicity Equipment & Supplies
10 equipment items found
Manufactured by:Elpiscience based inShanghai, CHINA
It has a unique mechanism of action as 4-1BB activation is dependent on PD-L1 binding. 4-1BB is a T cell co-stimulatory receptor and is a compelling immune checkpoint target. 4-1BB targeting antibodies being developed by multinational companies have exhibited dose-dependent liver toxicity in clinical trials, thereby limiting dose-escalation and ultimately their ...
Manufactured by:Wisdom Biological Technology Co.,Ltd based inPudong District, CHINA
The use of this product to develop and produce new products can improve the bioavailability of drugs, reduce the dosage, avoid direct stimulation of the gastrointestinal tract and liver first-pass, and reduce the liver toxicity of drugs. It is the first choice for research and development of new ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Investigate mechanisms of toxicity for preclinical drug candidates to help decrease clinical trial safety failures. Drug-induced liver injury (DILI) is a primary concern during drug development that remains poorly understood due to species differences in liver toxicity and the limited predictivity of conventional in vitro models. ...
by:Curadigm based inParis, FRANCE
Curadigm’s technology was developed to address a critical challenge facing intravenously administered therapeutics: How can you efficiently deliver a drug to your tissue of interest without rapid clearance? To address this, we developed technology that reduces unwanted hepatic clearance, resulting in a temporary increase in blood bioavailability so the therapeutic they can reach its ...
Manufactured by:Altimmune Inc. based inGaithersburg, MARYLAND (USA)
A peptide-based dual GLP-1/glucagon receptor agonist designed to treat the metabolic dysfunction that causes non-alcoholic steatohepatitis (NASH). NASH, the most severe form of non-alcoholic fatty liver disease (NAFLD), involves multiple metabolic pathways leading to the abnormal accumulation of liver fat, toxic lipid metabolites, and ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
3D InSight™ Animal Liver Microtissues. Delivering greater physiological relevance for investigative toxicology studies. Custom 3D InSight™ Animal Liver Microtissues are available only on request for research partners, who perform translational toxicology studies on a regular basis. We offer fully tested and highly standardized monkey, dog, and rat ...
Manufactured by:Innovad based inAntwerp, BELGIUM
The liver performs several essential functions related to digestion, metabolism, nutrient storage within the body as well as immunity. As this organ is the center of the metabolic activity, high producing animals with an ever increasing genetic potential severely stress the liver. Furthermore, toxic compounds such as medication, mycotoxins, ...
Manufactured by:Darnitsa Group based inKyiv, UKRAINE
Mineral supplements. Calcium drugs. Calcium gluconate. Calcium gluconate is a calcium salt of gluconic acid containing 9% calcium. Calcium ions are involved in nerve impulse transmission, smooth and skeletal muscle contraction, myocardial functioning, blood clotting processes; they are required for bone tissue formation, and normal functioning of other systems and ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder ...
Manufactured by:CanaQuest Medical Corp. based inMississauga, ONTARIO (CANADA)
Mentanine®, supported by (cannabidiol “CBD” + IP formula) – molecules bond and synergistically attach to PPAR receptors allowing the formula to cross the blood-brain barrier (BBB) to target the central nervous system (the brain) with amplified effects and efficacy. CBD by itself did not do this in the pre-clinical trials. Mentanine® is a natural pure ...