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Lung Inflammation Equipment & Supplies

32 equipment items found

T-COVID - Single-Dose Intranasal Therapeutic for the Treatment of Early Covid-19

T-COVID - Single-Dose Intranasal Therapeutic for the Treatment of Early Covid-19

Manufactured by:Altimmune Inc.   based inGaithersburg, MARYLAND (USA)
Identical vector technology used for AdCOVID (COVID-19), NasoVAX (seasonal influenza) and NasoShield (anthrax) ...
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ECO MEDICS EXHALYZER - Model D - Comprehensive Pulmonary Function Testing Device

ECO MEDICS EXHALYZER - Model D - Comprehensive Pulmonary Function Testing Device

Manufactured by:ECO MEDICS AG   based inDuernten, SWITZERLAND
Key features include a nitrogen washout bypass system for multiple washouts and an NO measurement module for non-invasive lung inflammation detection. The device operates optimally, unaffected by environmental conditions like temperature or humidity, and offers minimal airflow restriction ideal for infants. The accompanying SPIROWARE software facilitates ...
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YSOPIA - Model Yso3 - Preclinical Drug Development Program

YSOPIA - Model Yso3 - Preclinical Drug Development Program

by:Verb Biotics   based inBoston, MASSACHUSETTS (USA)
Yso3 is a preclinical drug development program aimed at treating asthma. Using a revolutionary form of living biotherapy targeting the lung, YSOPIA is pioneering the innovative field of the lung microbiome. As part of this program, YSOPIA has selected a clinical candidate having demonstrated strong in vivo efficacy on inflammation and ...
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TruDiagnostic - Model SYMPHONYAge - Comprehensive Aging Analysis Tool

TruDiagnostic - Model SYMPHONYAge - Comprehensive Aging Analysis Tool

by:TruDiagnostic   based inLexington, KENTUCKY (USA)
SYMPHONYAge (System Methylation Proxy of Heterogeneous Organ Years) offers a novel approach to understanding aging by evaluating how different parts of the body age both independently and synchronously. By analyzing 11 distinct organ systems, SYMPHONYAge provides insights into the interconnected patterns of aging that influence various health outcomes. This method contrasts with other biological ...
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Vertex - Cystic Fibrosis (CF)

Vertex - Cystic Fibrosis (CF)

by:Vertex Pharmaceuticals   based inBoston, MASSACHUSETTS (USA)
Cystic fibrosis (CF) is a rare, chronic and life-shortening genetic disease. It’s a progressive, multi-system disease that affects the lungs, liver, gastrointestinal tract, pancreas, sinuses, sweat glands and reproductive tract. In the lungs, this leads to the buildup of abnormally thick, sticky mucus that can cause chronic lung infections ...
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Operon - Simple/Stick Respiradeno Rapid Test Kit

Operon - Simple/Stick Respiradeno Rapid Test Kit

Manufactured by:Operon S.A.   based inCuarte de Huerva (Zaragoza), SPAIN
A single-step immunochromatographic test for the qualitative detection of respiratory Adenovirus in nasopharyngeal swab, wash, and aspirate respiratory samples. Adenovirus is a virus with double-stranded DNA, non-enveloped, belonging to the Adenoviridae family. Up to 55 different serotypes have been identified, of which types 3, 4, 7, and 14 are more commonly associated with respiratory ...
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MedChemExpress - Model Lirimilast - 329306-27-6

MedChemExpress - Model Lirimilast - 329306-27-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Lirimilast (BAY 19-8004) is a potent, selective and orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 value of 49 nM. Lirimilast can be used for the treatment of asthma or chronic obstructive pulmonary disease (COPD). Lirimilast has potently anti-inflammatory ...
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MedChemExpress - Model Crocin - 42553-65-1

MedChemExpress - Model Crocin - 42553-65-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Crocin (Crocin I) is an orally active natural product that can be isolated from the stigma of Crocus sativus. Crocin inhibits tumor cell proliferation and promotes apoptosis through JAK pathway. Crocin has anti-inflammatory, antioxidant and antitumor activities ...
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MedChemExpress - Model ADS032 - 2757333-37-0

MedChemExpress - Model ADS032 - 2757333-37-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
ADS032 is a sulfonylurea compound that is an NLRP1 and NLRP3 inflammasome inhibitor. ADS032 reduces the secretion of inflammatory factors and inhibits the oligomerization of ASC. ADS032 has anti-inflammatory effects in a variety of inflammatory models and can be used in the study of inflammatory ...
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MedChemExpress - Model RO5461111 - 1252637-46-9

MedChemExpress - Model RO5461111 - 1252637-46-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
RO5461111 a highly specific and orally active antagonist of Cathepsin S with IC50s of 0.4 nM (human Cathepsin S) and 0.5 nM (murine Cathepsin S), respectively. RO5461111 can effectively inhibit the activation of antigen-specific T cells and B cells. RO5461111 can improve pulmonary inflammation and lupus ...
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MedChemExpress - Model Isoliquiritigenin - 961-29-5

MedChemExpress - Model Isoliquiritigenin - 961-29-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 ...
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MedChemExpress - Model BMS-587101 - 509083-77-6

MedChemExpress - Model BMS-587101 - 509083-77-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
BMS-587101 is a potent and orally active antagonist of leukocyte function associated antigen-1 (LFA-1). BMS-587101 has anti-inflammatory effects and can be used for rheumatoid arthritis ...
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MedChemExpress - Model BC-1382 - 1013753-99-5

MedChemExpress - Model BC-1382 - 1013753-99-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction (IC50≈ 5 nM).Anti-inflammatory ...
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MedChemExpress - Model AF12198 - 185413-30-3

MedChemExpress - Model AF12198 - 185413-30-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM). AF12198 inhibits IL-1-induced IL-8 production (IC50=25 nM) and IL-1-induced intercellular adhesion molecule-1 (ICAM-1) expression (IC50=9 nM) in vitro. AF12198 has anti-inflammatory ...
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MedChemExpress - Model Clofoctol - 37693-01-9

MedChemExpress - Model Clofoctol - 37693-01-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral ...
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Airway Clearance Therapy with Afflovest

Airway Clearance Therapy with Afflovest

Manufactured by:Rotech Healthcare Inc.   based inOrlando, FLORIDA (USA)
Rotech offers the AffloVest, an airway clearance device that helps clear chest airways and can be used at home or anywhere. Quiet, portable, and easy-to-use, the AffloVest allows those with Bronchiectasis, Cystic Fibrosis, and other neuromuscular diseases to use airway clearance therapy without impairing quality of life. High-Frequency Chest Wall Oscillation (HFCWO) is an airway ...
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MedChemExpress - Model CAY10404 - 340267-36-9

MedChemExpress - Model CAY10404 - 340267-36-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
CAY10404 is a potent and selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 1 nM and a selectivity index (SI; COX-1 IC50/COX-2 IC50) of >500000. CAY10404 is a potent PKB/Akt and MAPK signaling pathways inhibitor and induces apoptosis in non-small cell lung cancer (NSCLC) cells. CAY10404, a diarylisoxazole, has good analgesic, anti-inflammatory, and anti-cancer ...
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MedChemExpress - Model Ro24-7429 - 139339-45-0

MedChemExpress - Model Ro24-7429 - 139339-45-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ro24-7429 is a potent and orally active HIV-1 transactivator protein Tat antagonist. Ro24-7429 is also a runt-related transcription factor 1 (RUNX1) inhibitor. Ro24-7429 has anti-HIV, antifibrotic and anti-inflammatory ...
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MedChemExpress - Model Lipoxin A4 - 89663-86-5

MedChemExpress - Model Lipoxin A4 - 89663-86-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties[1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways[2]. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of ...
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MedChemExpress - Model Naproxen - 22204-53-1

MedChemExpress - Model Naproxen - 22204-53-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell ...
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