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Medchemexpress Metabolism Disease Equipment & Supplies

18 equipment items found

MedChemExpress - Model 3-Hydroxyanthranilic acid - 548-93-6

MedChemExpress - Model 3-Hydroxyanthranilic acid - 548-93-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway.3-hydroxyanthranilic acid has anti-inflammatory, neuroprotective, and lipid-lowering effects. 3-hydroxyanthranilic acid can be used for researches of cardiovascular diseases, tumors, and metabolic ...
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MedChemExpress - Model Tridocosahexaenoylglycerol - 124596-98-1

MedChemExpress - Model Tridocosahexaenoylglycerol - 124596-98-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tridocosahexaenoylglycerol (TG-DHA) is an orally active dietary supplement that improves autoimmune encephalomyelitis in mice. Tridocosahexaenoylglycerol shows beneficial effects on neurodegenerative diseases and also improves macular function in diabetic retinopathy. Tridocosahexaenoylglycerol can be used for research on neurological diseases, inflammatory ...
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MedChemExpress - Model Lycorine - 476-28-8

MedChemExpress - Model Lycorine - 476-28-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Lycorine is also a melanoma vasculogenic inhibitor[3]. Lycorine can be used for the study of prostate cancer and metabolic ...
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MedChemExpress - Model Tridocosahexaenoylglycerol (Standard) - 124596-98-1

MedChemExpress - Model Tridocosahexaenoylglycerol (Standard) - 124596-98-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tridocosahexaenoylglycerol (TG-DHA) is an orally active dietary supplement that improves autoimmune encephalomyelitis in mice. Tridocosahexaenoylglycerol shows beneficial effects on neurodegenerative diseases and also improves macular function in diabetic retinopathy. Tridocosahexaenoylglycerol can be used for research on neurological diseases, inflammatory ...
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MedChemExpress - Model Valproic acid - 99-66-1

MedChemExpress - Model Valproic acid - 99-66-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine ...
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MedChemExpress - Model Phosphorylethanolamine - 1071-23-4

MedChemExpress - Model Phosphorylethanolamine - 1071-23-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of ...
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MedChemExpress - Model Valproic acid sodium - 1069-66-5

MedChemExpress - Model Valproic acid sodium - 1069-66-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine ...
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MedChemExpress - Model Monosialoganglioside GM3 (bovine) - 54827-14-4

MedChemExpress - Model Monosialoganglioside GM3 (bovine) - 54827-14-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Additionally, Monosialoganglioside GM3 (bovine) acts as an inhibitor of insulin signaling, inducing the dissociation of the insulin receptor (IR)-Caveolin-1 complex from lipid microdomains and causing insulin resistance in adipocytes. Monosialoganglioside GM3 (bovine) can be used in cancer and metabolic disease ...
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MedChemExpress - Model Manidipine dihydrochloride - 89226-75-5

MedChemExpress - Model Manidipine dihydrochloride - 89226-75-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Manidipine also exerts anti-inflammatory activity mediated by NF-κB and antiviral activity against many flavivirus and negative-strand RNA viruses through the inhibition of calcium channel. Manidipine is widely applied to research of cardiovascular, metabolic disease and ...
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MedChemExpress - Model N-Acetylcarnosine - 56353-15-2

MedChemExpress - Model N-Acetylcarnosine - 56353-15-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
N-Acetylcarnosine, a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic agent in human ...
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MedChemExpress - Model Acesulfame potassium - 55589-62-3

MedChemExpress - Model Acesulfame potassium - 55589-62-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Acesulfame potassium can suppress autophagic degradation of PD-L1 in RIL-175 and SK-Hep1 cells through the ERK1/2-mTORC1-ULK1 pathway, which may be related to immune evasion in cancer cells. Acesulfame potassium can be used in research on neurological diseases, metabolic disorders, cancer, and immune ...
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MedChemExpress - Model Probucol - 23288-49-5

MedChemExpress - Model Probucol - 23288-49-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Probucol also has anti-inflammatory, antioxidant and neuroprotective properties. Probucol can be used for researches on bone, cardiovascular, cancer, neurological, and metabolism-related ...
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MedChemExpress - Model Desmosterol - 313-04-2

MedChemExpress - Model Desmosterol - 313-04-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol ...
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MedChemExpress - Model Berberine sulfate - 633-66-9

MedChemExpress - Model Berberine sulfate - 633-66-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves ...
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MedChemExpress - Model Berberine - 2086-83-1

MedChemExpress - Model Berberine - 2086-83-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Berberine (Natural Yellow 18) is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine (Natural Yellow 18) induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine (Natural Yellow 18) has antineoplastic properties. The sulfate form (HY-N0716B) improves ...
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MedChemExpress - Model 4-Methyl-2-oxopentanoic acid - 816-66-0

MedChemExpress - Model 4-Methyl-2-oxopentanoic acid - 816-66-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid) is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways. 4-Methyl-2-oxopentanoic acid also causes oxidative damage, leading to ...
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MedChemExpress - Model BMS-963272 - 1441057-15-3

MedChemExpress - Model BMS-963272 - 1441057-15-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
BMS-963272 is an orally active and selective MGAT2 inhibitor (IC50 = 7.1 nM), used for the study of metabolic disorders and inflammatory ...
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MedChemExpress - Model Friedelin - 559-74-0

MedChemExpress - Model Friedelin - 559-74-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Friedelin is also a competitive inhibitor of CYP2E1, with IC50 and Ki values of 22.54 μM and 18.02 μM, respectively. Friedelin can be used in research related to inflammation, neurological diseases, and metabolic ...
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