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Microglial Activation Equipment & Supplies

18 equipment items found

Tests for Activation of Microglial Activation/Inflammatory Profile

Tests for Activation of Microglial Activation/Inflammatory Profile

Manufactured by:nVector   based inPhoenix, ARIZONA (USA)
These tests are quite valuable to be included in a biomarker “tool kit” that can be used for multiple neurologic diseases, as they measure activation of cell types that cause inflammation in the periphery and central nervous system. These tests will be incorporated in precision medicine programs for neurologic ...
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MedChemExpress - Model Methylene Blue - 61-73-4

MedChemExpress - Model Methylene Blue - 61-73-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Methylene blue is a REDOX cycling compound and able to cross the blood-brain barrier. Methylene blue is a Tau aggregation inhibitor. Methylene blue reduces cerebral edema, attenuated microglial activation and reduced ...
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MedChemExpress - Model Methylene blue hydrate - 122965-43-9

MedChemExpress - Model Methylene blue hydrate - 122965-43-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Methylene blue hydrate is a Tau aggregation inhibitor. Methylene blue hydrate reduces cerebral edema, attenuated microglial activation and reduced ...
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MedChemExpress - Model Methylene blue hydrate - 122965-43-9

MedChemExpress - Model Methylene blue hydrate - 122965-43-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Methylene blue hydrate is a Tau aggregation inhibitor. Methylene blue hydrate reduces cerebral edema, attenuated microglial activation and reduced ...
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TIKOMED ILB - Pleiotropic Mechanisms Drugs

TIKOMED ILB - Pleiotropic Mechanisms Drugs

by:TIKOMED AB   based inViken, SWEDEN
ILB’s mechanism of action may either reduce the triggers that lead to cell death or prevent further pathology even if triggers are present. By addressing the underlying processes of disease, ILB could significantly improve outcomes for people suffering from otherwise untreatable progressive and disabling ...
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MedChemExpress - Model Isoquinoline - 119-65-3

MedChemExpress - Model Isoquinoline - 119-65-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Isoquinoline is an analog of pyridine. Isoquinoline-based alkaloids, such as p-tolyl bisisoquinoline, phthaloyl isoquinoline, and naphthyl isoquinoline, exhibit anticancer activity.Berberine, an isoquinoline alkaloid, exerts anti-inflammatory effects in diabetic mice by downregulating the gene expression ratios of pro-/anti-inflammatory and Th1/Th2 cytokines.Additionally, some isoquinoline-based ...
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MedChemExpress - Model Rhynchophylline - 76-66-4

MedChemExpress - Model Rhynchophylline - 76-66-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum. Rhyncholphylline is an EphA4 inhibitor. It has high biological activity and is widely used in anti-inflammatory, neuroprotective and other ...
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Emulate - Brain-Chip

Emulate - Brain-Chip

Manufactured by:Emulate   based inBoston, MASSACHUSETTS (USA)
Research mechanisms of neuroinflammation and evaluate the effect of therapeutics in a comprehensive model of the neurovascular ...
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MedChemExpress - Model TBHQ - 1948-33-0

MedChemExpress - Model TBHQ - 1948-33-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
TBHQ (tert-Butylhydroquinone) is a widely used Nrf2 activator, protects against Doxorubicin (DOX)-induced cardiotoxicity through activation of Nrf2[1]. TBHQ (tert-Butylhydroquinone) is also an ERK activator; rescues Dehydrocorydaline (DHC)-induced cell proliferation inhibitionin ...
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MedChemExpress - Model Ethyl pyruvate - 617-35-6

MedChemExpress - Model Ethyl pyruvate - 617-35-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate. Ethyl pyruvate is an HMGB1 release inhibitor. Ethyl pyruvate can induce apoptosis by autophagy. Ethyl pyruvate has anti-inflammatory, antioxidant and anti-tumor activity. Ethyl pyruvate can be used in the study of neurodegenerative diseases such as Alzheimer's and Parkinson's ...
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MedChemExpress - Model Hispidulin - 1447-88-7

MedChemExpress - Model Hispidulin - 1447-88-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 ...
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MedChemExpress - Model Dexketoprofen (trometamol) - 156604-79-4

MedChemExpress - Model Dexketoprofen (trometamol) - 156604-79-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Dexketoprofen trometamol (Dexketoprofen tromethamine salt) is an orally active non-selective COX inhibitor. Dexketoprofen trometamol has a pain-relieving effect, anti-inflammatory effect and anti-cancer ...
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MedChemExpress - Model Scutellarin - 27740-01-8

MedChemExpress - Model Scutellarin - 27740-01-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC50s of 26 μM, 253 μM and 136 μM, ...
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MedChemExpress - Model P7C3 - 301353-96-8

MedChemExpress - Model P7C3 - 301353-96-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
P7C3 is an orally bioavailable and blood-brain barrier penetrant aminopropyl carbazole, with neuroprotective effects. P7C3 can be used for the research of neurodegenerative diseases, including Parkinson's ...
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MedChemExpress - Model Gabapentin-d4 - 1185039-20-6

MedChemExpress - Model Gabapentin-d4 - 1185039-20-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Gabapentin-d4 is the deuterium labeled Gabapentin. Gabapentin (Neurontin) is a pharmaceutical agent, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic ...
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MedChemExpress - Model PLP (139-151) - 131334-43-5

MedChemExpress - Model PLP (139-151) - 131334-43-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis ...
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MedChemExpress - Model Oxiracetam - 62613-82-5

MedChemExpress - Model Oxiracetam - 62613-82-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Oxiracetam (ISF2522) is an orally active and a BBB-penatrable cyclic derivative of γ-aminobutyric acid (GABA). Oxiracetam reaches the hippocampus and cerebral cortex in high concentrations. Oxiracetam can promote cognitive function and regulate inflammatory response, with powerful neuroprotective effects. Oxiracetam can be used in the study of central nervous system diseases[1][2][3] ...
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MedChemExpress - Model Tridocosahexaenoylglycerol - 124596-98-1

MedChemExpress - Model Tridocosahexaenoylglycerol - 124596-98-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tridocosahexaenoylglycerol (TG-DHA) is an orally active dietary supplement that improves autoimmune encephalomyelitis in mice. Tridocosahexaenoylglycerol shows beneficial effects on neurodegenerative diseases and also improves macular function in diabetic retinopathy. Tridocosahexaenoylglycerol can be used for research on neurological diseases, inflammatory immune diseases, and metabolic ...
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