Natural Killer Cell Equipment
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based in AUSTRALIA
The CORE-NK platform is a transformative platform technology for Chimeric enabling the accelerated development of multiple next generation, off the shelf NK and CAR-NK products. Natural killer cells are found in our bodies naturally and are able to recognize and kill cancer cells – but are not robust and ...
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based in FRANCE
CD160TM NK cell boost using CD160-TM specific monoclonal antibodies. Natural Killer cells (NK) represents a cell population involved in the cancer cell destruction through recognition of tumor cells followed by cell killing through ...
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Manufactured by Nkarta, Inc.based in USA
Cell therapy, a new approach that uses immune cells to attack tumors, has emerged as one of the most promising breakthroughs in cancer treatment. First generation approaches have focused on T-cells, which have shown great promise in hematologic malignancies but are plagued with unwanted side effects and, to date, have not shown similar ...
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based in AUSTRALIA
The next generation CORE-NK platform will integrate additional activation and expansion features to further optimize the cancer-fighting power of the CORE-NK platform cells. Development of the next generation CORE-NK platform will be as a combination therapy for blood ...
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Manufactured by Fate Therapeutics, Inc.based in USA
NK cells play a major role in the anti-tumor efficacy of certain tumor-antigen targeting antibodies. NK cells express CD16, an activating receptor that binds to the Fc portion of IgG antibodies. Once activated through CD16, NK cells are able to destroy antibody-coated target cells and secrete cytokines, such as interferon gamma, ...
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Manufactured by multimmune GmbHbased in GERMANY
ENKASTIM is based on the activation of immune cells called natural killer (NK) cells that are major players in the body's first line of defense, also called innate immunity. The immune effector cells are activated ex vivo (outside the body; ENKASTIM-ev) or in vivo (inside the body; ...
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Manufactured by Celularity Inc.based in USA
CYNK-001 is the only cryopreserved, allogeneic, off-the-shelf, natural killer (NK) cell therapy being developed from placental hematopoietic stem cells as a potential treatment option for various hematologic cancers, solid tumors, and infectious disease. NK cells are a unique class of immune ...
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Manufactured by multimmune GmbHbased in GERMANY
In vivo application of ENKASTIM-iv, an Hsp70-based GMP-grade synthetic peptide comprising 14 amino acids (14mer), results in a specific activation of NK cells which acquire the capacity to recognise and kill membrane Hsp70-positive tumors and ...
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Manufactured by Senti Biosciencesbased in USA
Natural Killer (NK) cells are essential components of the immune system, playing an important role in the body’s defensive response against tumors and infected cells. NK cells constantly patrol the body to detect and neutralize foreign cells. Senti Bio believes there are several advantages ...
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Manufactured by Celularity Inc.based in USA
CYNK-CAR candidates are being developed as allogeneic, off-the-shelf approaches through gene modification of human placental hematopoietic stem cell-derived natural killer (NK) cells. Various CAR constructs against hematological and solid tumor targets are under pre-clinical ...
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Manufactured by Sartorius CellGenix GmbHbased in GERMANY
CellGenix GMP SCGM is an optimized, xeno-free medium used for the serum-free expansion of low numbers of isolated human hematopoietic stem and progenitor cells (HSCs/CD34+ cells). In addition, our SCGM is proved to be highly efficient for the expansion and cultivation of human natural killer cells (NK ...
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Manufactured by Ativa Medicalbased in USA
Ativa's Diagnostic Workstation with a miniaturized flow-cytometer can measure the innate immune response cells in the blood. In COVID-19, Natural-Killer Cell activation occurs within hours of first infection, these cells fight the Virus in the lungs. Miniaturized low-cost diagnostic tests Immediate lab-quality ...
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Manufactured by Caprico Biotechnologies, Inc. (CBI)based in USA
The clone L243, a mouse monoclonal antibody, recognizes a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain known as human HLA-DR antigen. HLA-DR is widely expressed on monocytes, macrophages, activated T and B lymphocytes, activated natural killer (NK) cells, and ...
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Manufactured by Alphageneronbased in USA
Our lead clinical stage natural killer (NK) cell therapy, is an autologous platform technology that activates NK cells to kill cancers expressing a unique membrane form of Heat Shock Protein 70 ...
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Manufactured by Promega Corporationbased in USA
4-1BB (CD137/TNFRSF9), a member of the tumor necrosis factor receptor superfamily, is an inducible co-stimulatory receptor expressed on T cells, natural killer (NK) cells and innate immune cell populations. When present on the cell surface, 4-1BB interacts with 4-1BB ligand (4-1BBL) and induces ...
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Manufactured by Celyad Oncologybased in BELGIUM
CYAD-101 is an investigational, non-gene edited allogeneic (from healthy donor derived) CAR T candidate engineered to co-express the chimeric antigen receptor based on NKG2D, a receptor expressed on natural killer (NK) cells that binds to eight stress-induced ligands (NKG2DL) expressed by a broad range of tumor cells and the ...
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Manufactured by Celyad Oncologybased in BELGIUM
CYAD-02 is an investigational CAR T therapy that engineers an all-in-one vector approach in patient’s T cells to express both (i) the NKG2D chimeric antigen receptor, a receptor expressed on natural killer (NK) cells that binds to eight stress-induced ligands (NKG2DL) expressed on tumor cells, and (ii) ...
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based in USA
Natural killer (NK) cells, as their name implies, play an important role in ridding the body of cancer and viruses. NK cells are emerging as an increasingly important cell type for therapeutic development. Solid tumors are particularly challenging to treat and CAR-T cells have largely ...
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Manufactured by LAVA Therapeutics N.V.based in NETHERLANDS
uniquely activates both Vγ9Vδ2 T cells as well as invariant natural killer T cells, which represent another conserved immune effector cell population, in a target dependent manner. We plan to begin a Phase I/IIa clinical trial in patients with relapsed and/or refractory multiple myeloma and CLL in ...
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Manufactured by Kiadis Pharma NVbased in NETHERLANDS
Ushering in the Future of NK-cell Therapy: Natural killer (NK) cells have long been known to play a significant role in the body’s innate immune response. They were first described in the 1970s, but only in the last 15 years has significant progress been made in understanding the complexities and therapeutic potential these ...
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