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Aveo Pancreas Cancer Equipment & Supplies

2 equipment items found

AVEO - Model AV-203 - ErbB3 Signaling Inhibitory Antibody

AVEO - Model AV-203 - ErbB3 Signaling Inhibitory Antibody

Manufactured by:AVEO Pharmaceuticals, Inc.   based inBoston, MASSACHUSETTS (USA)
AV-203 (CAN017) is a clinical-stage ErbB3 (HER3) inhibitory antibody candidate designed to inhibit both ligand-dependent and ligand-independent ErbB3 signaling. ErbB3 is a receptor that is typically expressed in many human cancers, and AV-203 has demonstrated preclinical activity in a number of different tumor models including breast, head and neck, lung, ovarian and pancreatic ...
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AVEO - Model Ficlatuzumab - Investigational Drug (anti-HGF IgG1 mAb)

AVEO - Model Ficlatuzumab - Investigational Drug (anti-HGF IgG1 mAb)

Manufactured by:AVEO Pharmaceuticals, Inc.   based inBoston, MASSACHUSETTS (USA)
Ficlatuzumab (formerly known as AV-299) is a potent hepatocyte growth factor (HGF) immunoglobulin G1 (IgG1) inhibitory antibody that binds to the HGF ligand with high affinity and specificity. HGF is the natural ligand of c-Met and blocking HGF inhibits signaling through the HGF/c-Met signaling ...
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