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Pancreatic Colorectal Equipment & Supplies
19 equipment items found
by:Alfa Cytology based inU.S. VIRGIN ISLANDS
KRAS G12C inhibitor 61 inhibits phosphorylated ERK 1/2 in MIA PaCa-2 cells with an IC50 of 9 nM. KRAS G12C inhibitor 61 may be used in studies of pancreatic, colorectal, and lung cancers. ...
Manufactured by:BridgeBio Pharma, Inc. based inPalo Alto, CALIFORNIA (USA)
RAS is one of the most well-known oncogenic drivers, with approximately 30% of all cancers being driven by RAS mutations, including large proportions of lung, colorectal and pancreatic tumors. BridgeBio’s approach to RAS cancers encompasses multiple “shots on goal” that target both KRAS mutant tumors and those in which RAS activates PI3Ka. We ...
by:Alfa Cytology based inU.S. VIRGIN ISLANDS
Bis-Pro-5FU is a 5-FU precursor that confers oral bioavailability and improves the safety of 5-fluorouracil (5-FU) chemotherapy regimens. 5-FU is an antitumor antimetabolite that is widely used in colorectal and pancreatic cancer research. ...
by:Debiopharm based inLausanne, SWITZERLAND
Oxaliplatin is a diaminocyclohexane (DACH) platin. It is the active substance of the branded Eloxatin®/Elplat®/Dacotin®/Dacplat®, which has dramatically changed the prognosis of colorectal cancer. In 1996, prior to the introduction of oxaliplatin, the standard of care for colorectal cancer was 5-fluorouracil (5-FU). Combination of oxaliplatin with 5-FU and leucovorin (FOLFOX) ...
Manufactured by:Auris Medical AG based inBasel, SWITZERLAND
The OligoPhore™ / SemaPhore™ technology has been extensively and successfully tested with various siRNA and mRNA sequences in numerous disease models in mice. For the development of our first proprietary drug product, AM-401 (OligoPhore™ siRNA targeting KRAS), we have initiated a program of IND-enabling ...
by:Chimeric Therapeutics based inCarlton South, AUSTRALIA
CHM 2101 (CDH17 CAR T) is an optimized 3rd generation CAR T cell therapy that is the first to target ...
Manufactured by:BridgeBio Pharma, Inc. based inPalo Alto, CALIFORNIA (USA)
BridgeBio is developing SHP2 inhibitors as potentially effective additions to the therapeutic arsenal for difficult-to-treat cancers. SHP2, encoded by the PTPN11 gene, links growth factor signaling with the downstream RAS/ERK/MAPK pathway to regulate cell growth and division. Over-activity of this pathway, often driven by distinct gene mutations, causes or contributes to many human cancers. ...
Manufactured by:Xoft, Inc. based inSan Jose, CALIFORNIA (USA)
The versatile Xoft Axxent® Electronic Brachytherapy (eBx) System utilizes breakthrough electronic brachytherapy technology to provide expanded treatment options for a range of cancers. With the Axxent controller, highly focused therapeutic radiation of the disease target is possible in a minimally shielded setting, while sparing surrounding healthy ...
Manufactured by:Vitrosens Biotechnology A.S. based inÜmraniye, TURKEY
Test kit qualitatively detects tumor marker Carcinoembryonic Antigen (CEA) in human serum, plasma, and whole blood ...
Manufactured by:Xoft, Inc. based inSan Jose, CALIFORNIA (USA)
Our proprietary, miniaturized x-ray source is isotope-free and operates at 50 kV to deliver high dose rate, low energy radiation. The source is placed inside the applicator and energized to deliver a precise, prescribed dose of radiation. With the Xoft System, highly focused therapeutic radiation of the disease target is possible in a minimally shielded setting, while sparing surrounding healthy ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
KRAS mutation is found in several cancers such as pancreatic cancer, colorectal cancer, lung cancer, biliary tract cancer and thyroid cancer. The existence of KRAS mutations is often related with a prognostic marker to drug response. For example, KRAS mutation is considered a strong prognostic marker for drug response of tyrosine kinase inhibitors such as ...
Manufactured by:Xoft, Inc. based inSan Jose, CALIFORNIA (USA)
Xoft offers patients and physicians a simplified alternative to traditional six-week radiation therapy for early-stage breast cancer treatment. With the Xoft Axxent Electronic Brachytherapy (eBx) System, delivery of radiation therapy in the operating room at the time of surgery is possible with intraoperative radiation therapy ...
Manufactured by:Qualigen Therapeutics, Inc. based inCarlsbad, CALIFORNIA (USA)
RAS itself acts as a “hub” that activates multiple effector pathways and blocking any single pathway is ineffective for many tumor types, including pancreatic, lung, and colorectal ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Ensituximab (NEO-102; NPC-1C) is a chimeric monoclonal IgG1 antibody targeting a variant of MUC5AC. Ensituximab shows specificity to colorectal and pancreatic ...
Manufactured by:INOVIQ Ltd based inNotting Hill, AUSTRALIA
Studies have found that the analysis of exosome-associated nucleic acids, proteins and/or lipids can indicate the presence of a range of cancers, including pancreatic cancer, colorectal cancer [2], breast cancer [3], and non-small cell lung ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer ...
Manufactured by:Scancell based inOxford, UNITED KINGDOM
Glycosylation is a post-translational modification that occurs inside the cell and results in the addition of sugar motifs, “glycans”, to proteins and lipids that are, in most cases, destined for the cell surface. These glycan structures form the “glycome” and play an integral role in cell-to-cell and cell-to-matrix interactions through modulation of adhesion and cell ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
TAK-733 is a potent and selective MEK allosteric site inhibitor with an IC50 of 3.2 ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Terpinen-4-ol (4-Carvomenthenol) is a naturally occurring monoterpene, and can be extracted from a variety of aromatic plants. Terpinen-4-ol is a potent bactericidal agent which possess antifungal , anti-inflammatory and antitumor properties as well, suggesting Terpinen-4-ol to be used for relevant ...