Pharmacokinetic Equipment & Supplies
349 equipment items found
by:Vivozon Inc. based inYongin-si, SOUTH KOREA
A randomized, double-blind, placebo-controlled, single and repeated dose, escalation clinical trial to evaluate the safety, tolerability, and pharmacokinetics of VVZ-149 injection in healthy adult ...
by:Vivozon Inc. based inYongin-si, SOUTH KOREA
Single-dose, escalation clinical trial to evaluate the safety and pharmacokinetics of VVZ-149 injection in healthy elderly ...
Manufactured by:Vitalis, LLC based inNew York, NEW YORK (USA)
Aspirin is one of the oldest, most complex drugs in medicine, with many different indications and applications. It has unique pharmacokinetic properties where its metabolites effect aspirin itself, depending on the rates of metabolism in different parts of the ...
Manufactured by:Troikaa Pharmaceuticals Ltd. based inAhmedabad, INDIA
Dynapar QPS is the world's first Transdermal preparation of Diclofenac, which provides excellent pain relief after topical application, by enhancing the penetration of Diclofenac through the skin. Dynapar QPS is backed by proof of concept pharmacokinetic studies as well as clinical ...
by:Italfarmaco SpA based inMilan, ITALY
Nimedex (nimesulide in ß-cyclodextrin granules of 400 mg for oral suspension) combines the treatment benefits of the active ingredient nimesulide with the pharmacokinetic advantages of ß-cyclodextrin. The innovative formulation of Nimedex facilitates its solubilization, anticipates the absorption of the active ingredient and provides a quicker analgesic effect ...
Manufactured by:Tasso, Inc. based inSeattle, WASHINGTON (USA)
The Tasso-M20 device delivers whole dried blood samples from the patient to the lab. It can be used for PK (pharmacokinetic) monitoring in patients enrolled in clinical trials. Subjects can successfully collect volumetrically precise samples regardless of access to trial sites. The Tasso-M20 is CE marked and FDA ...
Manufactured by:Mersana Therapeutics based inCambridge, MASSACHUSETTS (USA)
Instead of direct conjugation to an antibody, drug molecules are attached through an optimized, cleavable linker to the Fleximer scaffold, which is then conjugated to the antibody through a non-cleavable linker. Fleximer dramatically improves drug solubility, pharmacokinetics, and immunogenicity, and significantly increases the number of drug molecules carried by each ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
mTOR inhibitor-3 is a remarkably selective mTOR inhibitor with a Ki of 1.5 nM. mTOR inhibitor-3 suppresses mTORC1 and mTORC2 in cellular and in vivo pharmacokinetic (PK)/pharmacodynamic (PD) ...
Manufactured by:BiomX based inNess Ziona, ISRAEL
Phase 1b/2a clinical study in CF patients is composed of two parts. Results from Part 1 aimed to evaluate the safety, pharmacokinetics, and microbiologic/clinical activity are expected in Q3 of 2022. Results from Part 2 aimed to demonstrate safety and efficacy are expected by Q1 of 2023. ...
Manufactured by:BiomX based inNess Ziona, ISRAEL
Although different organs are affected in IBD and PSC (gut in IBD and liver in PSC) the two diseases are thought to be related since approximately 70% of PSC patients also suffer from IBD. Results from a pharmacokinetic and safety Phase 1a study demonstrated safety and tolerability with successful delivery of a high concentration of viable phage to the lower gastrointestinal ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
GSK620 is a potent and orally active pan-BD2 inhibitor with excellent broad selectivity, developability and in vivo oral pharmacokinetics. GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Enpatoran can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran exhibits excellent pharmacokinetic properties in vivo. Enpatoran can be used for both innate and adaptive autoimmunity blocking research ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer ...
Manufactured by:Frontier Biotechnologies Inc. based inNanjing, CHINA
Frontier Biotech also filed an Investigational New Drug (IND) application for FB3001 in China and was granted approval by the National Medical Products Administration (NMPA) in March 2019. A Phase I bridging pharmacokinetic study has been ...
Manufactured by:Mersana Therapeutics based inCambridge, MASSACHUSETTS (USA)
Dolasynthen retains the favorable properties of Dolaflexin, including our proprietary DolaLock technology for a controlled bystander effect, with even better physicochemical and pharmacokinetic ...
Manufactured by:Lumencor based inBeaverton, OREGON (USA)
The VOLTA Scanner is particularly significant for drug discovery applications, allowing comprehensive characterization of pharmacokinetics and ion-channel interactions under various ...
by:Horizon Therapeutics plc based inSaint Kevin`s, IRELAND
A monoclonal antibody against insulin-like growth factor-1 receptor (IGF-1R). TED in Japan (OPTIC-J): Phase 3 randomized, placebo-controlled trial in Japan to evaluate TEPEZZA in patients with moderate-to-severe active ...
by:Sutro Biopharma Inc. based inSouth San Francisco, CALIFORNIA (USA)
Sutro’s cell-free expression technology provides a rapid and powerful platform for the discovery and development of antibodies that bind simultaneously to two separate antigens (bispecific ...
Manufactured by:Mablink Bioscience based inLyon, FRANCE
Most of the challenges of ADCs are linked to the hydrophobicity of the cytotoxic drugs used, which degrade the pharmacological properties of the antibody when attached to ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic non-parenchymal cells (NPCs) represent about 30% of the liver and are specialized cells which interact with hepatocytes for several functions. For this reason, liver co-cultures may increase the sensitivity of liver models for ADME/Tox-related research by recapitulating the complexity of a whole liver. "Mix NPCs" provides a mix of different types of liver cells, including Kupffer cells, ...