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Pharmacokinetic Modeling Physiology Based Pharmacokinetic Equipment & Supplies
383 equipment items found
Manufactured by:Regeneron Pharmaceuticals Inc. based inTarrytown, NEW YORK (USA)
Veloci-Bi allows for the generation of full-length bispecific antibodies similar to native antibodies that are amenable to production by standard antibody manufacturing techniques and likely to have favorable antibody-like pharmacokinetic properties. ...
by:Vivozon Inc. based inYongin-si, SOUTH KOREA
A randomized, double-blind, placebo-controlled, single and repeated dose, escalation clinical trial to evaluate the safety, tolerability, and pharmacokinetics of VVZ-149 injection in healthy adult ...
Manufactured by:Vitalis, LLC based inNew York, NEW YORK (USA)
Aspirin is one of the oldest, most complex drugs in medicine, with many different indications and applications. It has unique pharmacokinetic properties where its metabolites effect aspirin itself, depending on the rates of metabolism in different parts of the ...
by:Horizon Therapeutics plc based inSaint Kevin`s, IRELAND
A monoclonal antibody against insulin-like growth factor-1 receptor (IGF-1R). TED in Japan (OPTIC-J): Phase 3 randomized, placebo-controlled trial in Japan to evaluate TEPEZZA in patients with moderate-to-severe active ...
by:Vivozon Inc. based inYongin-si, SOUTH KOREA
Single-dose, escalation clinical trial to evaluate the safety and pharmacokinetics of VVZ-149 injection in healthy elderly ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
The PhysioMimix™ MPS-TL6 plate enables organ to organ crosstalk for multi-organ studies. The MPS-TL6 plate enables true 2-organ communication between a Transwell® and a Liver compartment in 6 independent wells, both with their own circular flow. Each Transwell compartment accommodates standard 24-well plate 0.33 cm2 Transwell® inserts. Each liver compartment contains an embedded ...
by:Sutro Biopharma Inc. based inSouth San Francisco, CALIFORNIA (USA)
Sutro’s cell-free expression technology provides a rapid and powerful platform for the discovery and development of antibodies that bind simultaneously to two separate antigens (bispecific ...
Manufactured by:Troikaa Pharmaceuticals Ltd. based inAhmedabad, INDIA
Dynapar QPS is the world's first Transdermal preparation of Diclofenac, which provides excellent pain relief after topical application, by enhancing the penetration of Diclofenac through the skin. Dynapar QPS is backed by proof of concept pharmacokinetic studies as well as clinical ...
Manufactured by:Troikaa Pharmaceuticals Ltd. based inAhmedabad, INDIA
To provide therapeutically meaningful extended delivery of drugs, Troikaa has developed Duo Phase Technology. Through this technology, the drug dose is split judiciously into two components, where one part delivers the drug immediately and the other releases the drug in a sustained release pattern. Thus drug delivery is biphasic and ensures the requisite pharmacokinetic profile. Drugs developed ...
Manufactured by:Mablink Bioscience based inLyon, FRANCE
Most of the challenges of ADCs are linked to the hydrophobicity of the cytotoxic drugs used, which degrade the pharmacological properties of the antibody when attached to ...
by:Italfarmaco SpA based inMilan, ITALY
Nimedex (nimesulide in ß-cyclodextrin granules of 400 mg for oral suspension) combines the treatment benefits of the active ingredient nimesulide with the pharmacokinetic advantages of ß-cyclodextrin. The innovative formulation of Nimedex facilitates its solubilization, anticipates the absorption of the active ingredient and provides a quicker analgesic effect compared with the other ...
Manufactured by:VECT-HORUS based inMARSEILLE, FRANCE
Vect-Horus has developed its “VECTrans®” breakthrough technology platform with the objective of making the ‘undruggable’ druggable by overcoming challenges of the BBB, and more generally biological barriers. VECTrans® is based on the specific design and optimization of ‘molecular vectors’ that, once conjugated to a payload, enable its delivery to target ...
Manufactured by:Arcomed AG based inKloten, SWITZERLAND
A new propofol pharmacokinetic-pharmacodynamic (PKePD) model was developed using bispectral index (BIS) as the targeted endpoint based on previously published data from 30 ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic non-parenchymal cells (NPCs) represent about 30% of the liver and are specialized cells which interact with hepatocytes for several functions. For this reason, liver co-cultures may increase the sensitivity of liver models for ADME/Tox-related research by recapitulating the complexity of a whole liver. "Mix NPCs" provides a mix of different types of liver cells, including Kupffer cells, ...
Manufactured by:Pfizer Inc. based in, NEW YORK (USA)
ALDACTAZIDE oral tablets contain: spironolactone 25 mg, hydrochlorothiazide 25 mg or spironolactone 50 mg, hydrochlorothiazide 50 ...
Manufactured by:Pharmigene, Inc. based inNeihu Dist, TAIWAN
Clodpgrel, an antiplatelet agents is indicated for the reduction of thrombotic events as follows: Recent MI, Recent Stroke or Established Peripheral Arterial Disease. For patients with a history of recent myocardial infarction (MI), recent stroke, or established peripheral arterial disease, Clopidogrel has been shown to reduce the rate of a combined endpoint of new ischemic stroke (fatal or not), ...
Manufactured by:Ahlstrom based inEspoo, FINLAND
Easy Collection - Reliable and Quantitative Analysis - Design for Automation. Ahlstrom AutoCollect card is designed for dried blood spot (DBS) microvolume sampling, transport and storage at ambient ...
Manufactured by:Cellworks Research India Private Limited based inBangalore, INDIA
The Cellworks Platform biosimulates how a patient’s unique cancer will respond to therapies prior to treatment and identifies novel drug combinations for treatment-refractory patients. Therapy biosimulation is the ability to predict the phenotype response of a human cell to an external stimulus, such as a drug ligand or radiation. We utilize this technology, to determine a patient’s ...
by:Zymeworks Inc based inVancouver, BRITISH COLUMBIA (CANADA)
with a modular suite of proprietary cytotoxins (cell-killing compounds), stable linkers, and conjugation technologies. A broader window of opportunity. Deliver potent cell-killing compounds specifically to diseased target cells with optimal safety and efficacy. ZymeLink™, a next-generation antibody drug conjugate (ADC) platform, is a suite of proprietary cytotoxins (cell-killing compounds), ...
Manufactured by:Cingulate based inKansas City, KANSAS (USA)
CTx-1301 utilizes a breakthrough multi-core formulation of dexmethylphenidate, a compound approved by the FDA for the treatment of ...