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Physiological Relevance Equipment & Supplies
39 equipment items found
by:BICO - The Bio Convergence Company based inBoston, MASSACHUSETTS (USA)
Create multimaterial constructs with a mix of crosslinking modalities thanks to six printheads. 6 printheads enabling more complex structures and physiologically relevant ...
Manufactured by:CELLINK based inBoston, MASSACHUSETTS (USA)
Create multimaterial constructs with a mix of crosslinking modalities thanks to six printheads. 6 printheads enabling more complex structures and physiologically relevant ...
by:Thermo Fisher Scientific, LIMS & Laboratory Software based inPhiladelphia, PENNSYLVANIA (USA)
Create physiologically relevant cell culture models. Gibco Human Plasma-like Medium (HPLM) is a new formulation designed to resemble the natural cellular environment found in the body, mimicking the metabolic profile of human plasma. The widely used classic synthetic cell culture media, including MEM, DMEM, RPMI 1640, and DMEM/F-12 contain glucose, amino acids, ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
3D InSight™ Animal Liver Microtissues. Delivering greater physiological relevance for investigative toxicology studies. Custom 3D InSight™ Animal Liver Microtissues are available only on request for research partners, who perform translational toxicology studies on a regular basis. We offer fully tested and highly standardized monkey, dog, and rat ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
The 3D InSight™ Steatosis Model is an advanced human disease model that enables you to screen compounds and investigate disease pathophysiology using a physiologically relevant human liver microtissue that recapitulates the first stage of non-alcoholic fatty liver disease: accumulation of lipids in liver hepatocytes. Available as an assay-ready model ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
The product is based on the OrganoPlate® 3-lane 40 with 3 adjacent channels per chip, including one perfused HUVEC tubule. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Blood Vessel HUVEC you can now take your vascular research to the next ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Caco-2 comprises 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Colon Caco-2 you can now easily take your intestinal research to the next level. ...
Manufactured by:Kirkstall Ltd. based inYork, UNITED KINGDOM
The QV500 cell culture chamber is a highly flexible research tool, ideal for academic use. Produced from medical-grade silicone, the chamber provides a leak proof seal, allowing continuous flow of media across and through cell cultures. The chamber has a common diameter with the wells in standard 24-well plates, allowing for protocols developed for static cultures to easily be transferred to the ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Alterations in the functionality of vascular smooth muscle cells are associated with the progression of pathological conditions such as inflammation, atherosclersosis or pulmonary hypertension. Our team manufactures, at scale, vascular smooth muscle cells derived from the iPSC line that best fits your project. This in vitro model provides reliable predictions on vasoactivity compound-induced ...
Manufactured by:Pinnacle Technology based inLawrence, KANSAS (USA)
Pinnacle offers a GLUTAMATE BIOSENSOR that is capable of providing real-time changes in glutamate concentration in the brains of rodents. The glutamate biosensor has outstanding performance characteristics and rejects all common electroactive interferents, including ascorbate. It has a linear range of at least 50 uM. We have successfully demonstrated that the glutamate biosensor works in vivo ...
Manufactured by:Pinnacle Technology based inLawrence, KANSAS (USA)
Pinnacle offers a GLUCOSE BIOSENSOR that is capable of providing real-time changes in glucose concentration in the brains of rodents. The glucose biosensor has outstanding performance characteristics and rejects all common electroactive interferents, including ascorbate. It has a linear range of at least 4 mM. We have successfully demonstrated that the glucose biosensor works in vivo and can ...
Manufactured by:Platypus Technologies, LLC based inMadison, WISCONSIN (USA)
In the Oris 3D Cell Invasion Assay, stoppers are used to create a central collagen-containing Detection Zone for cell invasion experiments. Cells are suspended in a thick layer of collagen surrounding a circular collagen Detection Zone. After incubation, invading cells move into the detection zone, where they can be unambiguously quantified using a microscope or a ...
Manufactured by:Pinnacle Technology based inLawrence, KANSAS (USA)
Pinnacle offers a LACTATE BIOSENSOR that is capable of providing real-time changes in lactate concentration in the brains of rodents. The lactate biosensor has outstanding performance characteristics and rejects all common electroactive interferents, including ascorbate. It has a linear range of at least 2 mM. We have successfully demonstrated that the lactate biosensor works in vivo and can ...
by:BICO - The Bio Convergence Company based inBoston, MASSACHUSETTS (USA)
Automated sorting and isolation of single spheroids and organoids. A game-changer in drug screening and other applications where standard 3D models will gradually replace traditional animal models. spheroONE is an innovative single large-particle sorter and dispenser which revolutionizes 3D cellular models handling. Using precision dispensing technology together with advanced image-based sorting ...
Manufactured by:mimiX Biotherapeutics based inBiel/Bienne, SWITZERLAND
Biologicals – Cells, spheroids, organoids- or non-biological particles are dispersed in a hydrogel precursor and loaded in the SIM carrier. A vertical vibration generated with sound is applied, and a pattern is generated within seconds. Crosslinking of the patterned particulates within the hydrogel is carried out by using different stimuli (light, enzymatic, thermal crosslinking) ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
Our Non-Alcoholic Fatty Liver Disorder (NAFLD)/NASH in vitro Services offer a preclinical tool to test therapeutics in a human-relevant model, replicating key disease phenotypes including fibrosis and reporting clinical biomarkers to allow translatability to clinical trials. ...
Manufactured by:mimiX Biotherapeutics based inBiel/Bienne, SWITZERLAND
Create biological architectures with sound. Sound Induced Morphogenesis (SIM) is a gentle, fast, and easy method to generate multi-cellular, spatially orchestrated tissue constructs using sound waves. This versatile method addresses necessities in the broad field of life sciences, finding application in tissue engineering, regenerative medicine, or pharmaceutical research for drug ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Vascular endothelial cells are involved in multiple processess including blood flow, vascular permeability or angiogenesis. Our team can manufacture endothelial cells from the iPSC line that best fits your project with a controlled and scalable process. Custom assays can be developed with this fully functional cell model to screen drug-induced effects on endothelial barrier permeability or 3D ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Astrocytes are essential players in neurodegenerative disease progression providing a valuable tool for drug discovery and disease modeling. Human iPSC-derived astrocytes generated with our standardized process express key identity markers and support co-culture with human iPSC-derived neurons. Our team can manufacture astrocytes at scale from the iPSC that best fits your project or work with ...
Manufactured by:ScienCell Research Laboratories based inCarlsbad, CALIFORNIA (USA)
They are also capable of trans-differentiating into myofibroblasts, suggesting a role in aberrant accumulation of matrix and fibrotic disorders. CMEC cultures provide an invaluable tool for understanding CMEC physiological and pathophysiological relevance in cardiac function and disease. ...