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Retinal Pigment Epithelium Cells Equipment & Supplies

13 equipment items found

Electrospinning - Retinal Pigment Epithelium

Electrospinning - Retinal Pigment Epithelium

Manufactured by:The Electrospinning Company Ltd.    based inDidcot, UNITED KINGDOM
Culture of retinal pigment epithelium cells on the Mimetix scaffold. The aim of this case study was to evaluate whether the Mimetix scaffold can mimic Bruch’s membrane and assess the attachment, proliferation and differentiation of human RPE cells (ARPE-19) cells within it as a treatment ...
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OpRegen - Advanced Dry Age-Related Macular Degeneration (Dry AMD)

OpRegen - Advanced Dry Age-Related Macular Degeneration (Dry AMD)

Manufactured by:Lineage Cell Therapeutics, Inc.   based inCarlsbad, CALIFORNIA (USA)
On December 20, 2021, Lineage announced that it has entered into an exclusive worldwide collaboration and license agreement with Roche and Genentech, a member of the Roche Group, for the development and commercialization of OpRegen for the treatment of ocular disorders, including advanced dry age-related macular degeneration (dry AMD) with geographic atrophy (GA) in a transaction worth up to $670 ...
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R:GEN - Macular Laser for Healthy RPE Regeneration

R:GEN - Macular Laser for Healthy RPE Regeneration

Manufactured by:Lutronic Vision   based inBillerica, MASSACHUSETTS (USA)
R:GEN is the only retinal laser proven to deliver safe, efficacious and precise targeting of Retinal Pigment Epithelium (RPE) cells. R:GEN’s proprietary Real-Time Feedback, Dual Dosimetry, and Auto Ramp-up technologies ensure precise targeting of RPE cells without damage to ...
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Retinal Pigment Epithelium (RPE)

Retinal Pigment Epithelium (RPE)

Manufactured by:Newcells Biotech Limited   based inNewcastle Upon Tyne, UNITED KINGDOM
A functional monolayer in vitro model of retinal pigment epithelial cells generated from human iPSCs for accurate prediction of clinical outcomes. The retinal pigment epithelial (RPE) cell model is composed of a monolayer of RPE cells cultured in 24-well Transwell® plates. ...
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Clearside - Gene Therapy Technology

Clearside - Gene Therapy Technology

Manufactured by:Clearside Biomedical   based inAlpharetta, GEORGIA (US) (USA)
We believe our platform offers the potential for safer, targeted ocular gene therapy without some of the risks of surgery and subretinal administration. Suprachoroidal administration of gene therapy could ultimately enhance access to care because it does not require specialized gene therapy surgery treatment centers. The procedure for suprachoroidal injection is conducted in an office setting and ...
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Age-Related Macular Degeneration

Age-Related Macular Degeneration

Manufactured by:HEALIOS K.K.   based inTokyo, JAPAN
The retina is a light-sensitive nerve layer (similar in function to the film in a camera), lining the inner surface of the human eye. In the retina, light signals are converted to electrical signals and transmitted to the brain via the optic nerve. Eventually, light signals are processed as vision in the visual cortex. In the center of the posterior pole of the human retina, there is a special ...
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iPSC - Regenerative Medicine

iPSC - Regenerative Medicine

Manufactured by:HEALIOS K.K.   based inTokyo, JAPAN
Induced pluripotent stem cells (iPSCs) are established by introducing several factors to somatic cells such as skin cells. iPSCs can differentiate into the cells of a various tissues or organs (pluripotency) and grow indefinitely (proliferation). The objective of iPSC regenerative medicine is to restore cellular function by replacing dysfunctional tissues with cell therapy medicines, which are ...
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MedChemExpress - Model BML-280 - 1158347-73-9

MedChemExpress - Model BML-280 - 1158347-73-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
BML-280 (VU0285655-1) is a potent and selective phospholipase D2 (PLD2) inhibitor. BML-280 has the ability to prevent caspase-3 cleavage and reduction in cell viability induced by high glucose. BML-280 can be used for rheumatoid arthritis ...
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MedChemExpress - Model alpha-Mangostin - 6147-11-1

MedChemExpress - Model alpha-Mangostin - 6147-11-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 ...
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MedChemExpress - Model Aflibercept - 862111-32-8

MedChemExpress - Model Aflibercept - 862111-32-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR1 and VEGFR2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular ...
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MedChemExpress - Model Aflibercept - 862111-32-8

MedChemExpress - Model Aflibercept - 862111-32-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR1 and VEGFR2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular ...
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MedChemExpress - Model Aflibercept (VEGF Trap) - 862111-32-8

MedChemExpress - Model Aflibercept (VEGF Trap) - 862111-32-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR1 and VEGFR2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular ...
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MedChemExpress - Model Astaxanthin - 472-61-7

MedChemExpress - Model Astaxanthin - 472-61-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin inhibits NF-κB and down-regulates VEGF in blood glucose. Astaxanthin exerts anti-cancer cell proliferation, increases apoptosis, impairs migration and invasion by activating PPARγ and reducing the expression of STAT3. Astaxanthin also has neuroprotective and anti-inflammatory activity and can be ...
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