Rna Interference Equipment & Supplies
7 equipment items found
Manufactured by:SomaGenics, Inc. based inSanta Cruz, CALIFORNIA (USA)
RNA interference (RNAi) is a naturally occurring process by which RNA molecules inhibit gene expression either pre- or post-transcriptionally. The discovery of RNAi led to a better understanding of gene regulation and opened the door to exciting new applications in research and therapeutics. ...
Manufactured by:OriGene Technologies, Inc. based inRockville, MARYLAND (USA)
OriGene offers pre-made lentiviral shRNA plasmid kits containing 4 sequence-verified expression cassettes that target your gene of interest. Each lentiviral cassette contains three major functional elements: shRNA, a puromycin selection marker & a tGFP reporter. With a guaranteed knockdown of ≥70%, these kits and our ready-to-use lenti-shRNA particles are a great option for studying ...
Manufactured by:OriGene Technologies, Inc. based inRockville, MARYLAND (USA)
Trilencer-27 siRNA kits contain Dicer-Substrate duplexes that provide two critical improvements over the use of traditional 21mer siRNA designs. It takes advantage of the natural processing by Dicer to produce 10-fold higher potency and specificity than shorter 21-mer siRNA forms. The 27-mer duplexes also evade mammalian interferon response when expressed in mammalian cells and initiate strong ...
Manufactured by:Biosettia Inc. based inSan Diego, CALIFORNIA (USA)
The shRNA expression is suppressed by Tet repressor (TetR) binding to the hybrid H1 promoter containing tetracycline operators (TetO) and RNA interference only takes place in the presence of tetracycline. The inducible RNAi system provides the option of expressing shRNA in certain period of ...
by:CIS Pharma AG based inBubendorf, SWITZERLAND
RNA interference (RNAi) is a mechanism used to defend against external invasion. Oligo- and poly-nucleotide based RNAi therapeutics comprise a high clinical potential for unmet medical diseases and are seen as promising approach to combat a number of different indications including oncology, genetic disorders, auto-immune disorders, orphan diseases and viral ...
Manufactured by:Scopus BioPharma based inNew York, NEW YORK (USA)
CO-sTiRNA™ is a highly selective and targeted gene therapy that silences the activity of the STAT3 gene by way of RNA interference. CO-sTiRNA™ also stimulates TLR9 receptors to activate the body’s immune defense to recognize and kill cancer ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (KATP) channels opener. Anti-inflammatory ...