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Small Molecule Drug Development With Protein Small Molecule Equipment & Supplies
29 equipment items found
Manufactured by:Krieger AG based inMuttenz, SWITZERLAND
With a starting minimum volume of 25 ml, the Micro Mixer range is the ideal tool to scale down your contained mixing processes under pressure or vacuum. Dissolution of expensive shear sensitive API's, proteins, Developing and processing small molecule and complex biologic drug candidates. Or just vacuum ...
Manufactured by:MorphoSys AG based inPlanegg, GERMANY
Peptides are an increasingly important class of drug. As natural ligands to many targets, they can combine agonistic or antagonistic activity with low toxicity risk and can be applied to disease targets, where small molecules or antibody-based drugs cannot be used. However, the number of therapeutic peptide drugs is held back by properties that are inherent to wild-type peptides. Namely, that ...
Manufactured by:Gerresheimer AG based inDüsseldorf, GERMANY
The on-body infusor for the subcutaneous application of small-molecule drugs is available for volumes up to 3 ml. It can be worn on the body. Typical applications are bolus and basal regimens over several ...
Manufactured by:Symberix, Inc. based inDurham, NORTH CAROLINA (USA)
Symberix is advancing a portfolio of first-in-class drug candidates for multiple adjunct and monotherapeutic indications. Our discovery platform enables precise targeting of bacteria implicated in intestinal toxicity and gastrointestinal disease. By identifying specific bacterial enzyme targets, we can develop small molecule drugs to block harmful bacterial activity without disrupting the ...
Manufactured by:Acousia Therapeutics GmbH based inTübingen, GERMANY
With its first clinical study underway, Acousia is taking significant strides towards achieving its goal of developing novel medicines that enhance and preserve natural hearing for patients with ...
Manufactured by:SomaGenics, Inc. based inSanta Cruz, CALIFORNIA (USA)
RNA interference (RNAi) is a naturally occurring process by which RNA molecules inhibit gene expression either pre- or post-transcriptionally. The discovery of RNAi led to a better understanding of gene regulation and opened the door to exciting new applications in research and therapeutics. The 2006 Nobel price was awarded in recognition of this revolutionary ...
by:Starpharma Holdings Limited based inMelbourne, AUSTRALIA
Starpharma’s DEP® technology provides enhanced therapeutic benefits to Antibody Drug Conjugates (ADCs) including greater homogeneity, site specific attachment, and higher drug antibody ratio (DAR), than conventional ADC approaches. The use of ADCs is an innovative and cutting-edge area in cancer therapy that continues to grow, and Starpharma has a number of partner programs in the area. ...
Manufactured by:ApiJect Systems, Corp. based inStamford, CONNECTICUT (USA)
Blow-Fill-Seal (BFS) is a globally-trusted aseptic packaging technology where the pharmaceutical-grade plastic container is made, filled with the liquid drug product, and sealed in a rapid, continuous process. BFS is used around the world to package billions of doses of both large and small molecule sterile drug products annually, including ...
by:Sibylla Biotech S.p.A. based inVerona, ITALY
In Silico: Identifying small molecules able to revolutionize drug discovery. The PPI-FIT technology allows the exploration of unique pharmacological targets represented by protein folding intermediates. This places Sibylla Biotech in the exclusive position of identifying hit/lead compounds with a mechanism of action never ...
Manufactured by:Bayer AG based inLeverkusen, GERMANY
Traditionally, many small molecule drugs follow the same basic mechanism of action to treat diseases: They inhibit the function of a target protein that has an active role in a disease. To do so, they require a tractable active binding site to occupy, which will result in protein function inhibition like blocking its enzymatic activity. But traditional small molecules can only block one single ...
by:AdAlta Limited based inBundoora, AUSTRALIA
An i-body is a human protein that belongs to the class of next generation antibodies. The i-body is built on the scaffold of a human protein and engineered with two loops that mimic the shape of shark antibodies. These loops are responsible for binding or interacting with a particular target (in circulation or on a cell) that is causing disease. i-bodies are identified and developed using our ...
Manufactured by:Symberix, Inc. based inDurham, NORTH CAROLINA (USA)
A microbiome is a collection of microorganisms (and their DNA) that occupy a particular location. The "human microbiome" is composed of trillions of tiny microbes (mostly bacteria) that thrive in our mouth, on our skin, and inside our gut. An individual's gut microbiome is a unique and diverse community of thousands of distinct bacterial species. The vast majority of these bacteria are not ...
Manufactured by:Jericho Sciences, LLC based inDurham (RTP), NORTH CAROLINA (USA)
Jericho is developing a new therapeutic drug for FIV infection in cats, working toward a New Animal Drug Application (NADA) with the FDA. Our ongoing studies indicate that Jericho’s small molecule drug candidate can reduce FIV virus levels in chronically-infected cats for many months in the absence of continuing treatment. Extensive testing also indicates that the drug candidate has a good ...
Manufactured by:Gerresheimer AG based inDüsseldorf, GERMANY
This belt-worn on-body drug delivery device for small-molecule drugs has been developed for our pharma partner EVER Pharma. The wearable device is used by Parkinson's disease patients for the administration of apomorphine to treat this long-term degenerative disorder of the central nervous system. This device is customizable to be used with suitable other drugs for other ...
Manufactured by:Entero Therapeutics, Inc. based inBoca Raton, FLORIDA (USA)
FW-ICI-AC is a niclosamide-based, oral, small molecule anti-inflammatory inhibitor therapy for the treatment of immune checkpoint inhibitor (ICI)-associated colitis and diarrhea in metastatic cancer patients. The PASSPORT clinical trial, a Phase 2a study to determine the safety and potential efficacy of niclosamide in the treatment of ICI-AC, received FDA IND clearance in Q4 ...
by:Starpharma Holdings Limited based inMelbourne, AUSTRALIA
DEP® radiotheranostic conjugates have the potential to minimise off-target toxicity, optimise pharmacokinetics and enhance efficacy when used alone or in combination with other therapeutic approaches. The versatility of Starpharma’s DEP® platform means it can be used with a wide range of therapies and types of molecules (e.g., small molecule drugs, peptides, antibodies, ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
Dr. UG is an AI platform for developing new drugs that is based on DEARGEN’s deep learning technology. It specializes in genome data analysis, biomarker prediction, molecule selection and optimization. DEARGEN discovers new disease targets with Dr.UG and further realizes precision medicine by designing small molecules for new ...
by:Lena Biosciences, Inc. based inAtlanta, GEORGIA (US) (USA)
Lena Biosciences offers a robust 3D cell culture system for routine, predictive testing in vitro. SeedEZ is a three-dimensional cell culture scaffold made of randomly oriented, inert glass microfibers. The diameter of microfibers is carefully optimized for long-term cell growth and repeat-dose drug testing. The microfibers are arranged in such a way that creates tiny pores for nutrients, gases, ...
Manufactured by:Entero Therapeutics, Inc. based inBoca Raton, FLORIDA (USA)
FW-UP is a niclosamide-based, oral small molecule anti-inflammatory inhibitor therapy for the treatment of ulcerative proctitis (UP) and ulcerative proctosigmoiditis (UPS). FW-UP is currently being investigated in a Phase 2b clinical trial study to study the safety and potential efficacy of niclosamide in patients with UP and ...
by:Alucent Biomedical Inc. based inSalt Lake City,, UTAH (USA)
The Alucent NVS Vessel Restoration System is designed to create a natural, stent-like scaffold using the body’s own tissue and processes. An all-in-one, integrated procedural system, Alucent NVS combines standard angioplasty techniques with a small molecule drug that when photoactivated, promotes extracellular matrix protein linking inside the vessel ...