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Taconic T And B Cell Equipment & Supplies
2 equipment items found
Manufactured by:Taconic Biosciences, Inc. based inRensselaer, NEW YORK (USA)
The Abb mouse was developed in the laboratory of Michael J. Grusby et al. of the Harvard School of Public Health. The model was created by targeting the H2-Ab1 gene in ES-D3 cells and injecting the targeted ES cells into C57BL/6 blastocysts. Resultant chimeras were backcrossed to C57BL/6 for 4 generations (N4). Taconic received stock from Tufts University in December 1991, and the mice were ...
Manufactured by:Taconic Biosciences, Inc. based inRensselaer, NEW YORK (USA)
In order to selectively inactivate genes in a tissue specific manner many laboratories have developed Cre transgenic mouse strains in which the Cre recombinase is expressed under the control of a tissue specific promoter. The Lck-Cre transgenic mouse uses the proximal promoter of the Lck (lymphocyte protein tyrosine kinase) gene, which is first expressed early in thymocyte development at the ...