Target Protein Equipment & Supplies
72 equipment items found
Manufactured by:Elabscience based inHouston, TEXAS (USA)
Western Blot (WB) is one of the most conventional biological experiments. SDS-PAGE gel is used to transfer the separated proteins to the membrane (such as PVDF membrane). Then, the target protein is detected by the specific antibody that recognizes the target protein, and the specific antibody is recognized by ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
PROTAC-Proteolysis targeting chimera is a technology that induces the Ubiquitin-Proteasome System (UPS) to degrade the target protein. When the target protein (Protein of Interest (POI)) is ubiquitinated by the ligase of E1, E2, E3, the proteasome recognizes that part of the ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
ADC (Antibody-drug conjugate) is a next-generation antibody-drug conjugate that has improved efficacy over existing antibodies. This drug combines the advantages of two factors: target specificity, which is a characteristic of an antibody, and cytotoxicity, which is a characteristic of a drug. Specifically, this is a technology focused on targeting and killing ...
Manufactured by:Beijing Meizheng Bio-Tech Co., Ltd based inYanqing District, CHINA
Glutathione S-transferase (GST) Gene Fustion System is a versatile system for the expression, purification, and detection of GST-tagged proteins produced in E. coli. Purification of GST-tagged proteins can be performed under very mild conditions, which preserves the function and antigenicity of the target ...
by:Sibylla Biotech S.p.A. based inVerona, ITALY
The PPI-FIT (Pharmacological Protein Inactivation by Folding Intermediate Targeting) technology, of which Sibylla is the exclusive licensee, is a paradigm shift in rational drug design. The basic task of drug design is to find a small molecule able to bind a biological target -such as a protein- so to modulate or block its ...
Manufactured by:Cellomics Technology, LLC based inHalethorpe, MARYLAND (USA)
CISH (Cytokine Inducible SH2 Containing Protein) contains a SH2 domain and a SOCS box domain. SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CISH may be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ...
Manufactured by:multimmune GmbH based inMunich, GERMANY
mi-APO is a targeted protein product with potential to be used for the treatment of most tumor types. The product targets surface-bound heat shock protein 70 (Hsp70). Surface-bound Hsp70 is a tumor-specific marker expressed on about 50-75% of various cancer entities, e.g. lung, colon, breast, pancreas. ...
Manufactured by:Massive Photonics GmbH based inMünchen, GERMANY
The Primary Antibody Labeling Kit from Massive Photonics is designed for advanced FAST DNA-PAINT imaging, specifically targeting mouse IgG kappa light chain or rabbit IgG primary antibodies. This kit leverages camelid single-domain antibodies (sdABs) coupled to DNA-PAINT sites optimized for rapid imaging and high signal-to-noise ratios. The incorporation of FAST sequences ...
Manufactured by:Scancell based inOxford, UNITED KINGDOM
ImmunoBody vaccines are designed to generate potent T cell responses capable of a broad anti-tumour effect. They are DNA vaccines that encode a protein in the form of an antibody, but the parts of the antibody that would normally bind to the target protein are replaced with epitopes from a cancer ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
NX-5948 (BTK-IN-24) is an orally active chimeric targeting molecule (CTM) that induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. NX-5948 mediates potent anti-inflammatory activity via BTK degradation with resultant inhibition of B cell activation. ...
Manufactured by:Rockland Immunochemicals, Inc. based inLimerick, PENNSYLVANIA (USA)
Rabbit IgG TrueBlot® is a unique horseradish peroxidase conjugated Anti-Rabbit IgG monoclonal secondary antibody. Rabbit IgG TrueBlot® enables detection of immunoblotted target protein bands, without hindrance by interfering immunoprecipitating immunoglobulin heavy and light chains. It is easy to generate publication-quality IP/Western Blot data with ...
Manufactured by:Bayer AG based inLeverkusen, GERMANY
Traditionally, many small molecule drugs follow the same basic mechanism of action to treat diseases: They inhibit the function of a target protein that has an active role in a disease. To do so, they require a tractable active binding site to occupy, which will result in protein function inhibition like blocking its enzymatic activity. But ...
by:CrystalsFirst GmbH based inMarburg, GERMANY
It’s application is independent from the modality: it can be used for non-covalent and covalent compounds. The technology is independent from the nature of the protein and has been successfully applied for over 30 different protein ...
Manufactured by:EirGenix, Inc based inNew Taipei City, TAIWAN
Product: EG74032 CRM197 Carrier Protein. Target: Carrier protein for conjugate vaccines. Status: GMP ...
Manufactured by:LenioBio GmbH based inDüsseldorf, GERMANY
Our ALiCE cell-free protein expression kits are designed with ease-of-use in mind. Using our simple protocol will take you from reaction set-up to expressed protein in under 48 hours. All it takes is your gene-of-interest cloned into one of our vectors and the ALiCE® lysate. No additional reagents, no extra steps, and no protein-specific optimizations. ...
by:Vir Biotechnology, Inc. based inSan Francisco, CALIFORNIA (USA)
Moving beyond more traditional approaches that are used to evoke adaptive immunity or that directly target pathogens, where the development of resistance can occur, we plan to target host proteins as a means of creating host-directed therapies with high barriers to resistance. We believe that by leveraging the power of innate immunity, we can ...
by:Vaxxinit based inDallas, TEXAS (USA)
We are developing an anti-tau product candidate that has the potential to address multiple neurodegenerative conditions, including AD, by targeting abnormal tau proteins alone and in potential combination with other pathological proteins such as Aβ to combat multiple pathological processes at ...
Manufactured by:Lipotek based inActon, AUSTRALIA
Lipokel is a self adjuvanting small molecule suitable for the formulation of recombinant protein vaccines. Lipokel is very effective at stimulating TLR2 receptors and can be formulated for nasal delivery of vaccines in powder ...
by:Sibylla Biotech S.p.A. based inVerona, ITALY
What makes us unique is the power of our computational platform, which enables us to reconstruct the series of conformational rearrangements underlying the process of protein folding at an atomistic level of ...
Manufactured by:Navigo Proteins GmbH based inHalle, GERMANY
Navigo Proteins’ Precision Targeting unit leverages its protein engineering expertise to create proprietary Affilin® molecules, harnessed to create optimized, next generation biopharmaceutical drugs in numerous fields of use. Navigo Proteins’ Affilin® platform benefits from the inherent engineerability, ...