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Targeted Delivery And Protein Equipment & Supplies
97 equipment items found
by:CrystalsFirst GmbH based inMarburg, GERMANY
Our proprietary technology SmartSoak® enables an up to 10X accelerated process in crystallography by solving the problems of crystal soaking. SmartSoak-enabled crystallographic screens deliver hit rates up to 30 %. It’s application is independent from the modality: it can be used for non-covalent and covalent compounds. The technology is independent from the nature of the protein and ...
by:LifeSensors Inc based inMalvern, DELAWARE (USA)
Ubiquitin is a small polypeptide that is conjugated via its C-terminus to an ε-amino group of lysine on a target protein; this conjugation is referred to as monoubiquitylation. Subsequently, additional ubiquitin moieties can be conjugated to the initial ubiquitin, utilizing any of seven lysine residues (K6, K11, K27, K29, K33, K48, K63) on the surface of ubiquitin; this ubiquitin chain ...
Manufactured by:EirGenix, Inc based inNew Taipei City, TAIWAN
Product: EG74032 CRM197 Carrier Protein. Target: Carrier protein for conjugate vaccines. Status: GMP ...
Manufactured by:LenioBio GmbH based inDüsseldorf, GERMANY
Our ALiCE cell-free protein expression kits are designed with ease-of-use in mind. Using our simple protocol will take you from reaction set-up to expressed protein in under 48 hours. All it takes is your gene-of-interest cloned into one of our vectors and the ALiCE® lysate. No additional reagents, no extra steps, and no protein-specific optimizations. ...
by:Vir Biotechnology, Inc. based inSan Francisco, CALIFORNIA (USA)
Moving beyond more traditional approaches that are used to evoke adaptive immunity or that directly target pathogens, where the development of resistance can occur, we plan to target host proteins as a means of creating host-directed therapies with high barriers to resistance. We believe that by leveraging the power of innate immunity, we can create medicines that break the ...
by:Vaxxinit based inDallas, TEXAS (USA)
We are developing an anti-tau product candidate that has the potential to address multiple neurodegenerative conditions, including AD, by targeting abnormal tau proteins alone and in potential combination with other pathological proteins such as Aβ to combat multiple pathological processes at ...
Manufactured by:Systasy Bioscience GmbH based inMunich, GERMANY
The proprietary splitSENSOR technology is a highly sensitive,flexible and easy-to-use reporter assay system to monitor various cellular events in living cells, including the activity of drug targets. Various cellular events, such as regulated protein-protein interactions, can be robustly and quantitatively measured both at the membrane and in the cytosol of the cell. This feature makes it, for ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
Agonist refers to substances that activate a specific target protein. It can easily be viewed as the opposite of inhibitor. Until now, Deargen's drug-target interaction (DTI) was predicted based on the binding affinity between the substance and the target protein, which causes barrier to distinguish between the inhibition and activation activity. In addition, the demand for agonist hit discovery ...
Manufactured by:Lipotek based inActon, AUSTRALIA
Lipokel is a self adjuvanting small molecule suitable for the formulation of recombinant protein vaccines. Lipokel is very effective at stimulating TLR2 receptors and can be formulated for nasal delivery of vaccines in powder ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
PROTAC-Proteolysis targeting chimera is a technology that induces the Ubiquitin-Proteasome System (UPS) to degrade the target protein. When the target protein (Protein of Interest (POI)) is ubiquitinated by the ligase of E1, E2, E3, the proteasome recognizes that part of the protein and degrades the protein. PROTAC is composed of a protein of interest, a ligand that binds to the E3 ligase, and ...
by:Sibylla Biotech S.p.A. based inVerona, ITALY
What makes us unique is the power of our computational platform, which enables us to reconstruct the series of conformational rearrangements underlying the process of protein folding at an atomistic level of ...
Manufactured by:Aurinia Pharmaceuticals Inc. based inVictoria, BRITISH COLUMBIA (CANADA)
AUR200 is a recombinant Fc fusion protein designed to specifically block B-cell Activating Factor, known as BAFF, and A Proliferation-Inducing Ligand, known as APRIL. BAFF and APRIL promote B cell survival and differentiation and have been shown to play a prominent role in the pathogenesis of certain autoimmune and nephrology conditions. AUR200 is currently undergoing pre-clinical development ...
by:DEARGEN Inc. based inDaejeon, SOUTH KOREA
To hinder or inhibit the function of proteins that cause disease, many pharmaceutical companies develop drugs called inhibitors. Each of the 20,000 proteins in the human body has its own unique functions. Depending on the function of the protein, it can be classified into enzyme proteins, ion channel proteins, transport proteins, defense proteins, and structural proteins. Problems with the ...
Manufactured by:LifeTein, LLC based inHillsborough, NEW JERSEY (USA)
LifeTein’s unique coupling chemistry enables fast and efficient conjugation of amino (-NH2) or thiol (-SH) containing proteins and peptides, to the solid core with iron oxide clusters. All steps in the coupling are performed at physiological conditions and at room temperature with high yields and short reaction times. The Amine-Terminated Magnetic Beads are silica-based superparamagnetic ...
Manufactured by:Elabscience based inHouston, TEXAS (USA)
Western Blot (WB) is one of the most conventional biological experiments. SDS-PAGE gel is used to transfer the separated proteins to the membrane (such as PVDF membrane). Then, the target protein is detected by the specific antibody that recognizes the target protein, and the specific antibody is recognized by the labeled second antibody. The technique is widely used to detect the expression of ...
Manufactured by:Navigo Proteins GmbH based inHalle, GERMANY
Navigo Proteins’ Precision Targeting unit leverages its protein engineering expertise to create proprietary Affilin® molecules, harnessed to create optimized, next generation biopharmaceutical drugs in numerous fields of use. Navigo Proteins’ Affilin® platform benefits from the inherent engineerability, stability, safety, and ease of manufacturability. Our Precision Targeting ...
Manufactured by:Massive Photonics GmbH based inMünchen, GERMANY
The Primary Antibody Labeling Kit from Massive Photonics is designed for advanced FAST DNA-PAINT imaging, specifically targeting mouse IgG kappa light chain or rabbit IgG primary antibodies. This kit leverages camelid single-domain antibodies (sdABs) coupled to DNA-PAINT sites optimized for rapid imaging and high signal-to-noise ratios. The incorporation of FAST sequences significantly reduces ...
by:BellBrook Labs based inMadison, WISCONSIN (USA)
AptaFluor SAH Methyltransferase Assay directly measures SAH produced by methyltransferase enzymes during methylation. These enzymes methylate a variety of substrates using S-adenosylmethionine (SAM) as the methyl donor, leaving the common product S-adenosylhomocysteine (SAH). These SAH measurements allow researchers to effectively determine the activity of the methyltransferase enzyme. The ...
Manufactured by:CD BioSciences based inShirley, NEW YORK (USA)
Full length Clone DNA of Rhesus tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide with C terminal His ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
Revvity’s gene delivery team, where SIRION Biotech’s expertise lives on, has been partnering with pharma and biotech organizations for many years to provide improved viral vectors using our AAV ...