Therapeutic Potential Equipment
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based in USA
An alpha (α)-secretase modulator for ameliorating Alzheimer’s Disease pathophysiology and cognitive impairment with neuroprotection. Aphios is developing APH-1104, a more potent analog of Bryostatin-1, which is neuroprotective by α-secretase activation via novel PKC isoforms, down-regulation of pro-inflammatory and angiogenic processes and the substitution of β-amyloid for ...
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based in AUSTRALIA
DEP® docetaxel is an enhanced version of docetaxel (Taxotere®) – widely used for breast, lung & prostate cancer. Docetaxel (Taxotere®) is a commonly used chemotherapy agent despite having multiple US FDA “Black Box” warnings. DEP® docetaxel is a detergent free, aqueous formulation of docetaxel. ...
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based in USA
therapies have the potential to achieve long-lasting disease amelioration for chronic neurological disorders that lack effective treatment options, from a single, one-time dose. In this way, neural cell therapies can be ...
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Manufactured by Boston Pharmaceuticalsbased in USA
BOS-704 is a ghrelin O-acyl transferase inhibitor with therapeutic potential for multiple ...
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Manufactured by Boston Pharmaceuticalsbased in USA
BOS-857 is a first-in-class, inhaled, small molecule furin inhibitor with therapeutic potential in pulmonary diseases, including cystic fibrosis (CF), vascular diseases, and infectious ...
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based in SWITZERLAND
Orion’s platform and science unlocks the therapeutic potential of GPCR targets across a broad range of medical needs. Our approach allows us to focus our discovery and development efforts across peptide and protein GPCR subfamilies, generating a diversified pipeline of potential first-in-class/best-in-class ...
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based in USA
pathogen neutralization and immune system stimulation. We engineer the fully-human antibodies that we discover to enhance their therapeutic potential. ...
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Manufactured by Altucell, Inc.based in USA
Encapsulated cell therapy is an emerging area of biopharmaceutical research that aims to unleash the therapeutic potential of cells to treat serious diseases without the need for immunosuppression. Altucell has developed patented, proprietary engineered cells that are combined with a patented encapsulation technology to create ...
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Manufactured by Boston Pharmaceuticalsbased in USA
BOS-981 is a first-in-class, small molecule furin inhibitor with therapeutic potential in pulmonary diseases, including cystic fibrosis (CF), vascular diseases, and infectious ...
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Manufactured by Kymab, a Sanofi companybased in UNITED KINGDOM
Accessing a new repertoire of targets. Two classes of molecule with therapeutic potential that are not currently addressed by antibody drugs are G-protein-coupled receptors and ion channels, largely because they display small epitopes not accessible to traditional antibodies and their sequence is often conserved and thus less ...
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by Verb Bioticsbased in USA
the effectiveness of these cancer immunotherapies. YSOPIA is exploring the role of specific keystone bacteria with high therapeutic potential in the oncology field based on a strong understanding of their mechanisms of ...
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Manufactured by Inversago Pharmabased in CANADA
is still strongly supported by comprehensive scientific evidence and remains to be fully exploited. CB1 receptor world expert Dr George Kunos from US NIH has extensively demonstrated that peripherally-acting CB1 blockade provides an equivalent therapeutic potential to treat metabolic conditions such as obesity/NASH/T2D and fibrosis (liver and ...
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Manufactured by Sangamo Therapeuticsbased in USA
Sangamo’s proprietary zinc finger (ZF) platform uniquely confers a number of advantages and has broad therapeutic potential due to its versatility, specificity and clinical utility. Zinc finger technologies are composed of a DNA-binding domain, which binds with precision to any sequence of DNA, and various functional ...
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Manufactured by Feldan Therapeuticsbased in CANADA
We have designed the Feldan Shuttle, a versatile biotechnology that enables safe and efficient delivery of therapeutic compounds into cells. By giving access to intracellular space, this unique technology is unlocking the potential of therapeutics that target intracellular components and contributes to the development of revolutionary ...
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Manufactured by Regeneron Pharmaceuticals Inc.based in USA
VelociMab is a group of technologies that allow us to move with unprecedented speed from identification of a therapeutic antibody into clinical studies. VelociMab enables the high-throughput screening of potential therapeutic antibodies and the rapid generation of cell lines for recombinant human antibodies. It allows researchers to go from ...
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Manufactured by Regeneron Pharmaceuticals Inc.based in USA
VelocImmune is our unique technology for producing fully human monoclonal antibodies. VelocImmune creates a multitude of optimized antibody drug candidates efficiently and directly from immunized mice. This approach overcomes the limitations of traditional platforms by rapidly creating fully human antibodies that tightly bind to ...
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Manufactured by Juvena Therapeutics, inc.based in USA
Secreted proteins are a proven class of biologics with tremendous therapeutic potential, as they regulate tissue repair and regeneration, organ development, and immune response to disease. The characteristics of secreted proteins render them a rich pool of drug candidates for chronic and age-related diseases. Our therapeutic approach is to ...
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Manufactured by Ampersand Biosciencesbased in USA
Angiopoietin-related protein 7 (ANGPTL7), UniProt # O43827, is a 40kDa protein initially discovered in the cornea stromal layer. Increased levels have been observed in glaucoma and ANGPTL7 has been associated with various cancers including hepatic cancer metastasis. Studies have shown plasma levels are increased in obesity making it a ...
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Manufactured by EnteroBiotix Ltdbased in UNITED KINGDOM
The gut-liver-brain axis describes the interplay of immune, metabolic and neuroendocrine biology that is increasingly being recognised as a potential therapeutic ...
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Manufactured by Ampersand Biosciencesbased in USA
Angiopoietin-related protein 7 (ANGPTL7), UniProt # O43827, is a 40kDa protein initially discovered in the cornea stromal layer. Increased levels have been observed in glaucoma and ANGPTL7 has been associated with various cancers including hepatic cancer metastasis. Studies have shown plasma levels are increased in obesity making it a ...
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