Tumor Angiogenesis Equipment & Supplies
48 equipment items found
Manufactured by:Fate Therapeutics, Inc. based inSan Diego, CALIFORNIA (USA)
B7H3 belongs to the B7 family of immune checkpoint inhibitors and is expressed on a wide range of solid and hematologic malignancies. B7H3 is an important mediator of tumor angiogenesis and metastasis, and higher expression is associated with a poor prognosis for patients. We are developing FT573, an investigational, universal, off-the-shelf NK cell cancer ...
Manufactured by:Elthera AG based inSchlieren, SWITZERLAND
L1 cell adhesion molecule (L1CAM) is a cell surface protein which is aberrantly expressed in many different tumor types including pancreatic, ovarian, breast, lung, and colorectal cancer. L1CAM expression increases the malignancy of these tumors by promoting cellular proliferation, metastatic spread, tumor angiogenesis, ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Chiauranib (CS2164) is an orally active multi-target inhibitor against tumor angiogenesis. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-related kinase Aurora B, and chronic inflammation-related kinase CSF-1R, with IC50 values ranging from 1-9 nM. ...
Manufactured by:Echelon Biosciences, Inc (EBI) based inSalt Lake City, UTAH (USA)
Lysophosphatidic Acid (LPA) is a small lysophospholipid involved in diverse cellular processes such as cell proliferation, chemotaxis, platelet aggregation, wound healing, angiogenesis, tumor invasion, and smooth muscle contraction. LPA binds to several G-coupled protein receptors to initiate its biological functions. In cancer, LPA primarily promotes cell ...
Manufactured by:BUHLMANN Diagnostics Corp based inAmherst, NEW HAMPSHIRE (USA)
Flow CAST® Support in Drug Development: Inhibition of Basophil Activation is a Surrogate Biomarker for the Activity of Kinase ...
Manufactured by:PharmAbcine Inc. based inYuseong-gu, SOUTH KOREA
Olinvacimab is an anti-angiogenic antibody that neutralizes the VEGF/VEGFR2 pathway, thus inhibiting tumor growth and ...
Manufactured by:nanoPET Pharma GmbH based inBerlin, GERMANY
Viscover™ provides you with the first dedicated product portfolio of animal contrast agents to unleash the full potential of pre-clinical animal MRI, employing innovative agents from small molecules to nanoparticles. Our GadoSpin™ gadolinium chelate and FeraSpin™ iron oxide nanoparticle product families were designed to offer you previously unseen capabilities. ...
Manufactured by:General Medical Merate S.p.A. (GMM) based inSeriate, ITALY
Highly versatile digital mammographic system with the latest FFDM and DBT technology, suitable for both screening and diagnostic mammography. Viola DBT Compact Design offers a wide range of functions, such as conventional 2D mammography, DBT (with synthetic image G-View), stereotactic or tomo-guided biopsies with close to 360° approach and Dual Energy (CESM). Thanks to the single-column stand ...
Manufactured by:IMS Giotto S.p.A based inSasso Marconi, ITALY
Advanced and innovative breast tomosynthesis system including the integrated capability to generate full-field digital mammography (FFDM) images. It offers a wide range of functions, such as FFDM, DBT (with optional synthetic image G-View), Dual Energy (CESM) and image-guided biopsy. Featuring a unique and ergonomic design to ensure patient comfort and easiness for the operator: the gantry is ...
Manufactured by:IMS Giotto S.p.A based inSasso Marconi, ITALY
Highly versatile digital mammographic system with the latest FFDM and DBT technology, suitable for both screening and diagnostic mammography. GIOTTO CLASS S offers a wide range of functions, such as conventional 2D mammography, DBT (with synthetic image G-View), stereotactic or tomo-guided biopsies with close to 360° approach and Dual Energy (CESM). Thanks to the single-column stand the ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES104 is a bispecific antibody that simultaneously blocks Delta-like ligand 4/Notch (DLL4) and vascular endothelial growth factor A (VEGF-A) signaling pathways, which are critical to angiogenesis and tumor vascularization. VEGF also plays an important role in creating an immune suppressive TME. Pre-clinical and early clinical data of ES104 show that blocking both ...
Manufactured by:General Medical Merate S.p.A. (GMM) based inSeriate, ITALY
Advanced and innovative breast tomosynthesis system including the integrated capability to generate full-field digital mammography (FFDM) images. It features a unique and ergonomic design which ensures patient comfort and easiness for the operator: the gantry is able to reach different positions, including the horizontal one for interventional procedures. A high-precision tomo-guided biopsy kit ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Steppogenin is a potent inhibitor of HIF-1α and DLL4, with IC50 values of 0.56 and 8.46 μM, respectively. Steppogenin can be sued for the research of angiogenic diseases, such as those involving solid ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Sorafenib-d3 (Donafenib), a deuterated compound of Sorafenib, is the first deuterium-generation tumor suppressor small molecule. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Sorafenib Tosylate (Bay 43-9006 Tosylate) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. SorafenibTosylate is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib Tosylate induces autophagy and apoptosis. Sorafenib Tosylate has anti-tumor activity. ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Isosorbide mononitrate (Isosorbide-5-mononitrate) is an orally active nitric acid compound used for angina pectoris by dilating blood vessels and lowering blood pressure. Isosorbide mononitrate increases the viability and proliferation of HUVECs by decreasing Apoptosis and elevated the expressions of vedf, kdrl, pdgfr in zebrafish embryos. Isosorbide mononitrate is promising for research of heart ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Altiratinib (DCC-2701) is a multi-targeted kinase inhibitor with IC50s of 2.7, 8, 9.2, 9.3, 0.85, 4.6, 0.83 nM for MET, TIE2, VEGFR2, FLT3, Trk1, Trk2, and Trk3 ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Roxithromycin (RU-28965) is an orally active semi-synthethic macrolide antibiotic. Roxithromycin inhibits protein biosynthesis in the elongation step by binding to 50S bacterial ribosome. Roxithromycin has antimicrobial, antiproliferative, anti-inflammatory, tumour vasculature inhibiting and lung injury ameliorating ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
EOC317 (ACTB-1003) is an oral kinase inhibitor with IC50s of 6, 2 and 4 nM for FGFR1, VEGFR2 and ...