Upcyte - Liver Sinusoidal Endothelial Cells

Liver sinusoidal endothelial cells (LSECs) are highly specialized cells that form the scavenger endothelium within the liver. They exhibit extraordinarily high uptake of soluble waste molecules (< 0.23 µm), thus playing an important role in blood clearance. The supply of primary LSECs is limited by the low and sporadic availability of human liver tissue and can only be kept for up to 1-2 population doublings in culture. upcyte® LSECs were derived from primary LSECs from a single donor. These cells have an extended lifespan whilst maintaining primary cell characteristics. This means that large batches of up to 3000 vials from a single donor with the same quality can be provided.