1919
Eikichi Nemoto starts medical device wholesale business. The private enterprise is named Iwashiya Nemoto Eikichi Shoten.

1947
Manufacturing of operating tables is initiated at a specialized factory in Tokyo.

1951
The corporate name is amended to Mizuho Ikakogyo Co., Ltd.

1973
The Sugita Aneurysm Clip is developed.

1993
Mizuho America, Inc. is established in the U.S.

1999
The Gosen factory is completed.

2002
Acquires Orthopedic Systems,Inc. (California, USA)

2007
Mizuho(Thailand) Co.,Ltd. is established in Ayutthaya, Thailand.

2011
Shanghai office is established.

2013
Bangkok office is established. The Chiba factory is completed.

2014
The corporate name is amended to MIZUHO Co., Ltd.

2018
Bangkok office is temporally closed.

MIKSY -Malleable Instruments for Keyhole Surgery