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NanoAssemblr Blaze -Microliter Nanomedicine Formulations Device System

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The NanoAssemblr® Blaze allows rapid scaling of nanoparticle formulations for late pre-clinical development. The system can manufacture between 10 mL and 10 L of formulation which allows researchers to use the Blaze for preclinical toxicology testing, and for early Chemistry, Manufacturing and Controls (CMC) studies.

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SPEEDY AND EFFICIENT
Efficient formulation for large preclinical studies.

EASY SCALE-UP
Easy scale-up of formulations developed on the NanoAssemblr® Ignite.

HIGH CAPACITY
Greater formulation capacity with the simplicity and efficiency of the NanoAssemblr® Ignite.

VALIDATION OF INLINE DILUTION
Validation of Inline Dilution up to 5L, up to 50 L with Blaze+.

HIGH RANGE OF FORMULATION
Formulation of 10 mL to 1L batches, up to 10 L with the Blaze+.

SCALABLE UPSTREAM AND DOWNSTREAM
Scale-up development of upstream and downstream processes.

  • Up to 10 Liters per formulation
  • Connect bioprocess bags for closed system
  • Reduce cost by performing process development in house
  • Accelerate timelines by performing large scale formulations
Using the same microfluidic geometry, formulations are scalable across the NanoAssemblr® platform. This greatly reduces process and formulation redevelopment when changing scales, compared to conventional batch-based methodologies. LNPs containing nucleic acids maintain identical size and PDI when scaled across the platform.