Mobilized Leukopak
Mobilized Leukopaks are apheresis products collected from healthy donors treated with FDA-approved drugs to stimulate the migration of CD34+ hematopoietic stem and progenitor cells (HSPCs) from the bone marrow niche into the circulation. Mobilized peripheral blood, enriched in single-donor CD34+ HSPCs is collected through leukapheresis using the Spectra Optia® Apheresis System’s continuous flow centrifugal technology. The ease of collection and high yield of single-donor CD34+ cells is a major advantage to researchers to gain experimental consistency and scalability. AllCells is the industry leader in supplying mobilized Leukopaks with the shortest lead time on the market. We have six different mobilization regimens available using G-CSF (Neupogen®), plerixafor (Mozobil®), or a combination of the two drugs as well as CD34+ cells isolated from mobilized Leukopaks. Whole Mobilized Apheresis Tissue, Isolated Cells: CD34+ HSPCs
Whole Tissue: Healthy, consenting donors are subcutaneously injected by our qualified clinicians using the following regimen guidelines:
Isolated Cells: CD34+ HSPCs isolated from any of the mobilized leukapheresis collections are available. Positive immunomagnetic separation is used where CD34+ beads bind to target cells in the heterogeneous population - CD34+ cells remain bound to the beads while unwanted cells are removed.
AllCells offers fresh and cryopreserved Mobilized Leukopaks in a variety of types and sizes. The product chart below provides detailed information on standard formats, anticoagulants and unit sizes for both cellular and non-cellular Mobilized Leukopaks Don’t see what you’re looking for? Our Mobilized Leukopak products can also be Made-to-order (MTO) with custom specifications to meet the specific requirements of your research project. For more information on Mobilized Leukopak MTO, please visit our MTO page or reach out to our Customer Success Team. Need immediate help? Chat with a live agent now.
AllCells' on-site collection and processing facilities enables us to offer custom, made-to-order (MTO) products to meet the unique needs of our customers. From tissue collection to product shipment, AllCells’ experienced team of experts will help you define, design, and deliver your customized primary cell material.
We can accommodate specific donor requests, custom mobilization regimens requirements, bulk isolations, cryopreservation needs and more.