Model AMVUTTRA - Prescription Medicine
AMVUTTRA™ (vutrisiran) is a prescription medicine given once every 3 months by a healthcare professional to treat the polyneuropathy caused by an illness called hereditary ATTR (hATTR) amyloidosis in adults. In an 18-month clinical study, AMVUTTRA-treated patients showed significant improvement in nerve function and quality of life at 9 months and continued to improve throughout the study, compared with those who received placebo.
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Significant improvement in nerve functiona
- Significant improvement in nerve functiona
- Quality of life Significant improvement in quality of life
- Calendar Dosing once every 3 months
Education Is Available for You And Your Family
Can provide education to help you and your family better understand hATTR amyloidosis and answer your questions about AMVUTTRA.
PELs are employees of Alnylam Pharmaceuticals. They are not acting as healthcare providers and are not part of your healthcare team.
Get personalized support through Alnylam Assist™Alnylam Assist is a comprehensive patient support program designed to help you get started on treatment, understand your insurance coverage, discuss financial assistance options if you are eligible, and provide you with ongoing support in your treatment journey.
Important Safety Information
What are the most important things I should know about AMVUTTRA™ (vutrisiran)?
AMVUTTRA can cause:
- Low Vitamin A Levels
Treatment with AMVUTTRA lowers the amount of vitamin A in your blood. Your doctor will tell you to take a vitamin A supplement every day. You should not take more than the amount of vitamin A recommended by your doctor.
Low vitamin A levels can affect vision. If you have problems with your vision (e.g., night blindness) while taking AMVUTTRA, talk to your doctor. Your doctor may refer you to an eye specialist.
What are the common side effects of AMVUTTRA?
The most common side effects of AMVUTTRA are pain in the joints (arthralgia), shortness of breath (dyspnea), and low vitamin A levels.
These are not all the possible side effects of AMVUTTRA. Talk to your doctor about side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the U.S. Food and Drug Administration (FDA). Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Indication
What is AMVUTTRA?
AMVUTTRA is a prescription medicine that treats the polyneuropathy caused by an illness called hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis). AMVUTTRA is used in adults only.
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