Model SB-061 - Therapeutic Bioconjugate Molecule
SB-061, a therapeutic bioconjugate molecule inspired by the properties of aggrecan, is a drug delivered directly to the joint via intra-articular injection. SB-061 directly targets and inhibits the degrading extracellular matrix within the joint cavity, halting the matrix-induced inflammatory cycle that drives the signs and symptoms of progressive osteoarthritis. The goal of this approach is to both modify the course of disease by reducing joint degradation and to decrease symptoms due to inflammation. SB-061 is in clinical development for patients with osteoarthritis of the knee with effusions.
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