Model SMEDDS - Incrementally Modified Drugs (IMD)
Self-microemulsifying drug delivery system (SMEDDS) is a solubilization technology for improving bioavailability of poorly soluble drugs. By combining surfactant and co-surfactant with a poorly soluble drug, this technology improves the bioavailability of the drug by forming fine emulsion droplets upon dilution with physiological fluid after administration. This proprietary technology utilized SMEDDS technology to solubilize the poorly soluble drug, and further adsorbed the mixture to the solid carriers in order to prepare them into tablets, which enabled solidification of soft capsules into tablets and overcome the shortcomings of temperature-sensitive soft capsules and increase the convenience of administration.
Details
- Self-microemulsifying drug delivery system (SMEDDS), one of the solubilizing technologies for poorly soluble drugs, is a technology that improves the solubility and bioavailability of poorly soluble drugs by mixing surfactant, co-surfactant, oil, and the drug at the optimum ratio.
- JW Pharmaceutical's proprietary technology, which overcomes the shortcomings and limitations of existing poorly soluble drug formulations and improves the solubility and bioavailability of drugs to maximize drug safety and ease of administration.
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