Entero -Model 5-HT4 -Multiple GI Indications Receptor
Capeserod is a selective 5-HT4 receptor partial agonist, which Entero Therapeutics is repurposing and developing for multiple GI conditions. Based on the biological evidence of expression of 5-HT4b receptor subtype in human GI tract, Entero Therapeutics believes that capeserod may directly or indirectly initiate the peristaltic or secretory reflex by releasing neurotransmitters that can decrease colonic transit time and improve bowel movement.