LEON - Nanodrugs Technology

Because we take a bottom-up approach to particle synthesis, we avoid the known difficulties associated with top-down nano methods, such as wet-milling, where the presence of heat and the impact of shearing, together with the inherently high investment cost and the high failure rate, make it an unsuitable option for many candidate molecules and their organizations.

LEON can quickly and reliably produce a wide range of nano particles by customizing process conditions to the API. These include surface-stabilized nanocrystals, micelles, liposomes, nanoemulsions, polymeric nanoparticles and even solid lipid nanoparticles. Our proprietary approach shares the same fundamental process for small-scale testing as it does for full-scale production, providing a swift and cost-effective route to commercial development.

A solvent and non-solvent collide inside the reactor’s chamber.

This results in the precipitation of insoluble compounds.

Nanoparticles suspended in the liquid are ready for downstream processing.

LEON offers a broad range of particle types to meet a variety of requirements, whenever there is a need to re-produce easily and with scale, including:

• SURFACE-STABILISED CRYTALLINE NANOPARTICLES
• POLYMERIC NANOPARTICLES
• LIPOSOMES
• SOLID-LIPID NANOPARTICLES
• NANOEMULSIONS
• MICELLES