Show results for
Refine by
Medical Equipment & Supplies Near Belize
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
VRT-043198, the agent metabolite of VX-765 (Belnacasan), is a potent, selective and blood-brain barrier permeable inhibitor of interleukin-converting enzyme/caspase-1 subfamily caspases. VRT-043198 exhibits Ki values of 0.8 nM and 0.6 nM for ICE/caspase-1 and caspase-4, ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
FTY720 (S)-Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
MS67 is a potent and selective WD40 repeat domain protein 5 (WDR5) degrader with a Kd of 63 nM. MS67 is inactive against other protein methyltransferases, kinases, GPCRs, ion channels, and transporters. MS67 shows potent acticancer ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
CDDO-Im (RTA-403) is an activator of Nrf2 and PPAR, with Kis of 232 and 344 nM for PPARα and ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Alirocumab (anti-PCSK9) is an anti-PCSK9 human monoclonal antibody. Alirocumab (anti-PCSK9) inhibits PCSK9. Alirocumab (anti-PCSK9) reduces NLRP3 inflammasome, regulates Nrf2/HO-1, HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab (anti-PCSK9) increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab (anti-PCSK9) improves atherosclerosis and ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Betamethasone hydrochloride is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone hydrochloride accelerates fetal lung maturation and induces gene expression and ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Azelastine, an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone[1]. Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Substance P Receptor Antagonist 1 has the potential function in central nervous system disorders, respiratory, inflammatory diseases and gastrointestinal ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Uridine triphosphate (UTP) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound P2Y2 ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Atiratecan (TP300) is a proagent of camptothecin analog CH0793076 (HY-107096). Atiratecan does not inhibit acetylcholinesterase (AChE) activities. Atiratecan shows antitumor activity against both breast cancer resistance protein (BCRP)-positive and -negative xenografts in mouse xenograft ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Vandetanib trifluoroacetate (D6474 trifluoroacetate) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib trifluoroacetate also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
LY-2584702 hydrochloride is a selective ATP competitive inhibitor of p70S6K with an IC50 of 4 nM. In S6K1 enzyme assay, the IC50 of LY-2584702 is 2 ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Lenalidomide hydrochloride (CC-5013 hydrochloride), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hydrochloride is an orally active immunomodulator. Lenalidomide hydrochloride (CC-5013 hydrochloride) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
N-Acetylcarnosine, a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic agent in human ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa monohydrate is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa monohydrate inhibits pancreatic cancer cell and tumor ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC50=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities[1]. Anticancer ...
Manufactured by:MedChemExpress LLC (MCE)Â Â based inMonmouth Junction, NEW JERSEY (USA)
Coenzyme Q0 (CoQ0) is a potent, oral active ubiquinone compound can be derived from Antrodia cinnamomea. Coenzyme Q0 induces apoptosis and autophagy, suppresses of HER-2/AKT/mTOR signaling to potentiate the apoptosis and autophagy mechanisms. Coenzyme Q0 regulates NFκB/AP-1 activation and enhances Nrf2 stabilization in attenuation of inflammation and redox imbalance. Coenzyme Q0 has ...