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Cancer Study Equipment & Supplies Near Malta
3 equipment items found
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
JNJ-16241199 (R306465) is an orally active, selectivehydroxamate-based histone deacetylase (HDAC) inhibitor, with theIC50of 3.3 nM and 23 nM for HDAC1and HDAC8, respectively.JNJ-16241199induces histone 3 acetylation and strongly increasesthe expression of p21waf1, cip1 in A2780 ovarian carcinoma cells.JNJ-16241199 inducescell apoptosisand shows anticancer activityin a broad spectrum of human ...
Manufactured by:The Menarini Group based inFlorence, ITALY
Elacestrant is a selective estrogen receptor degrader (SERD) evaluated for potential use as a once daily oral treatment in patients with estrogen receptor positive (ER+)/HER2- advanced or metastatic breast cancer. Studies completed to date, including the positive results from the EMERALD phase 3 trial, indicate that the compound has the potential for use as a ...
Manufactured by:Quansys Biosciences Inc. based inLogan, UTAH (USA)
Decreased adiponectin levels are associated with metabolic disorders, including non-alcoholic fatty liver disease, obesity, type 2 diabetes, insulin resistance, and atherosclerosis, as well as some cancers. Studies suggest that the hormone promotes the synthesis of HDL cholesterol and low levels of adiponectin are associated with high triglyceride counts. ...