Boston - Model BOS-228 - Novel Monobactam

BOS-228 is a novel monobactam for infections caused by multidrug-resistant carbapenem-resistant Enterobacteriaceae.

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BOS-228 provides single-agent coverage of both metallo- and serine-β-lactamase producing Enterobacteriaceae unlike others in the same class.
Clinical PK and in vivo PK/PD studies support attainment of efficacious clinical exposures.

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