Nucleix EpiC - Model Platform - Ultra-Sensitive Liquid-Biopsy Technology
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DNA methylation
DNA methylation is a layer of epigenetic information on top of the DNA sequence. While the DNA sequence in all tissues is almost identical, unique methylation patterns determine each tissue’s biological identity. In cancer there are broad changes in methylation patterns, which makes DNA methylation an excellent type of marker for cancer.
Leveraging PCR-based epigenetics, our pioneering testing approach uses methylation-based identification for early-stage and recurring cancer detection. Our platform delivers highly accurate and sensitive results, all while providing a seamless testing option for patients and the healthcare system. Nucleix was built around DNA methylation expertise, and we were the first to develop a methylation-based tissue identification assay1,2. The EpiCheck assay determines the methylation profile of a liquid biopsy sample in a simple and cost-effective, yet extremely sensitive and accurate manner. EpiCheck can detect extremely rare cancerous molecules on a background of a large number of normal molecules.
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