Taconic -Model NMRI -Outbred Mouse Model
Origin: The NMRI outbred model was developed by Lynch et al. Poiley of the National Institutes of Health received stock from Lynch in 1937. The mice were inbred as NIH/P1. The Naval Medical Research Institute (NMRI) received stock from Lynch. Zentralinstitut für Versuchstierzucht in Hannover Germany (Han) received stock from NMRI. The mice were random bred. M&B A/S (now Taconic Europe) received stock from Han in 1961 and again in 1985. The mice are maintained as an outbred stock.
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- Extensively used as an experimental animal in many fields of general biology as well as in pharmacology and toxicology
- Commonly used as a control for selection experiments
- Develops a wide variety of spontaneous tumors and an increasing incidence of renal disease with age
Genetics: Immunology: H2q
Coat Color Loci: A/a, Tyrc
Color: Albino
Species: Mouse
Animal Diet: NIH #31M Rodent Diet