Demei - Model CAS 59-46-1 - Procaine White Powder for Drug
Procaine CAS 59-46-1 Excellent Quality Strong Supply Ability High quality High Purity Best Price. It has a role as a local anaesthetic, a central nervous system depressant, a peripheral nervous system drug and a drug allergen.
- Density: 1.1±0.1 g/cm3
- Boiling Point: 373.6±22.0 °C at 760 mmHg
- Melting Point: 61oC
- Molecular Formula: C13H20N2O2
- Molecular Weight: 236.310
- Flash Point: 179.8±22.3 °C
- Exact Mass: 236.152481
- PSA: 55.56000
- LogP: 2.36
- Vapour Pressure: 0.0±0.8 mmHg at 25°C
- Index of Refraction: 1.543
- Appearance : White Solid
Procaine is very quickly metabolizedin the plasma by cholinesterases and in the liver via ester hydrolysisby a pseudocholinesterase. The in vitroelimination half-life is approximately 60 seconds. Any conditionthat decreases the cholinesterase concentration may increaseexposure to procaine and potential toxicity. Decreasedenzyme activity can be found with genetic deficiency, liverdisease, malignancy, malnutrition, renal failure, burns, thirdtrimester of pregnancy, and following cardiopulmonary bypasssurgery. Ester hydrolysis produces PABA, the compoundresponsible for the allergic reactions common to theester anesthetics. Procaine is not used topically because of itsinability to pass through lipid membranes and finds use as aninfiltration agent for cutaneous or mucous membranes, forshort procedures. Procaine is also used for peripheral nerveblock and as an epidural agent to diagnose pain syndromes.