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- Revvity - Adenoviral Vectors
Revvity - Adenoviral Vectors
Adenoviral vectors offer high levels of transgene expression in broad cell types, including dividing and non-dividing cells. Adenoviral vectors are the method of choice whenever fast and transient gene expression for a very large gene or several genes is required, since the expression cassette has a total capacity of 7.5 kb. This provides space for flexible vector design with multiple transgenes delivered in one vector. Vaccine development is another popular application for adenoviral vectors. The ability of adenovirus to induce immune response in vivo makes it a great tool for vaccine studies. Revvity’s gene delivery portfolio, where SIRION Biotech’s expertise lives on, offers three technology platforms for supporting therapy developers working with adenoviral vectors.
- Transient gene expression in vivo and in vitro
- No host genome integration
- Large packaging capacity up to 7.5 kb gives a space for multiple gene expression cassettes
- Reliable gene delivery into dividing and non-dividing cells with almost 100% efficiency
- Fast results- gene expression
- Adenovirus remains epichromosomal and therefore does not integrate in the genome nor interfere with other host genes