Serrapeptase

Pharmacological action

• Anti-inflammatory, swelling effect: 1 Inflammatory model of rats with thermal burns, vascular hyperpermeability can be inhibited after oral administration; 2 Oral can inhibit inflammatory edema of rat skin induced by anti-rat serum, It can inhibit cross-dish gum, dextran and serotonin. Rat inflammatory edema caused by various inflammatory substances such as bradykinin; 3 has strong ability to decompose inflammatory peptide bradykinin in vitro; 4 has strong solvency for fibrin and fibrin .
• Promote the sputum, the dissolution and excretion of the concentrated solution: 1 for patients with chronic paranasal sinusitis, the dry matter weight in the nasal sputum is reduced, the viscosity is decreased; 2 for rabbits exposed to sulfur dioxide gas and suffering from subacute bronchitis, The viscosity of the mash is significantly reduced.
• The role of promoting the displacement of antibiotics to the lesion: for patients with chronic paranasal sinusitis, it can promote the migration of ampicillin to the maxillary sinus.

Physical and chemical properties

• Temperature range ：10 ° C ~ 60 ° C, the optimum temperature is 40 ° C ~ 50 ° C.
• Effective pH range ：6.0~10.0, the best PH7.0~9.0.

Product specifications

• Solid dosage form ：A yellowish solid powder with an enzyme activity of 2,000,000 IU/g;
• Enzyme activity definition ：One nerepeptidase unit (IU) is equivalent to the amount of enzyme required to produce 1 ug of tyrosine per minute under the specified conditions (pH 9.0, 37 ° C) (product standard: Japanese Pharmacopoeia).

Applications

Serrapeptase has the function of decomposing mucus and pus, which can make liquefied liquefaction, accelerate the elimination, and promote cell renewal. It can help the antibiotics to metastasize to the lesion and enhance the antibiotic antibacterial effect.

Packaging and storage

• Store ：Store at 4~5°C in cold storage. Under this storage condition, the shelf life of this product is 2 years.
• Package ：25L plastic.